Assignee
BOLDER BIOTECHNOLOGY INC
US·34 granted patents·10 pending applications·988 citations·filing 1998–2021
Top patents by PatentIndex Score
44 records- 0199US6608183B1Derivatives of growth hormone and related proteinsBOLDER BIOTECHNOLOGY INC·Filed 1998·Granted Aug 19, 2003·275 cites·87 claims
- 0298US6753165B1Methods for making proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2000·Granted Jun 22, 2004·144 cites·54 claims
- 0397US7399839B2Monopegylated growth hormone proteinsBOLDER BIOTECHNOLOGY INC·Filed 2005·Granted Jul 15, 2008·36 cites·42 claims
- 0497US7148333B2Cysteine variants of granulocyte-macrophage colony-stimulating factorBOLDER BIOTECHNOLOGY INC·Filed 2003·Granted Dec 12, 2006·56 cites·29 claims
- 0596US7495087B2Cysteine muteins in the C-D loop of human interleukin-11BOLDER BIOTECHNOLOGY INC·Filed 2006·Granted Feb 24, 2009·25 cites·6 claims
- 0696US7345149B2Cysteine substitution variants of beta interferonBOLDER BIOTECHNOLOGY INC·Filed 2005·Granted Mar 18, 2008·21 cites·25 claims
- 0795US7253267B2Cysteine variants of interleukin-11BOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Aug 7, 2007·32 cites·2 claims
- 0894US7309781B2Cysteine variants of granulocyte colony-stimulating factorBOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Dec 18, 2007·32 cites·48 claims
- 0994US7306931B2Method for refolding proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2001·Granted Dec 11, 2007·38 cites·49 claims
- 1094US7270809B2Cysteine variants of alpha interferon-2BOLDER BIOTECHNOLOGY INC·Filed 2003·Granted Sep 18, 2007·38 cites·22 claims
- 1194US7232885B2Termini cysteine-added variants of granulocyte colony stimulating factorBOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Jun 19, 2007·30 cites·11 claims
- 1294US7214779B2Termini cysteine-added variants of granulocyte-macrophage colony stimulating factorBOLDER BIOTECHNOLOGY INC·Filed 2004·Granted May 8, 2007·31 cites·5 claims
- 1393US7959909B2Cysteine variants of interferon gammaBOLDER BIOTECHNOLOGY INC·Filed 2007·Granted Jun 14, 2011·10 cites·16 claims
- 1493US7795396B2COOH-terminally added cysteine variant of the beta interferonBOLDER BIOTECHNOLOGY INC·Filed 2005·Granted Sep 14, 2010·11 cites·13 claims
- 1593US7345154B2Cysteine variants of erythropoietinBOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Mar 18, 2008·26 cites·4 claims
- 1693US7314921B2Cysteine variants of erythropoietinBOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Jan 1, 2008·26 cites·7 claims
- 1792US7994124B2Methods of use of G-CSF cysteine muteinsBOLDER BIOTECHNOLOGY INC·Filed 2009·Granted Aug 9, 2011·14 cites·28 claims
- 1892US7964184B2Cysteine variants of interferon-gammaBOLDER BIOTECHNOLOGY INC·Filed 2007·Granted Jun 21, 2011·9 cites·12 claims
- 1992US7824669B2In vivo stimulation of peripheral blood progenitor cells by granulocyte-macrophage colony stimulating factor (GM-CSF) cysteine muteins and their PEGylated variantsBOLDER BIOTECHNOLOGY INC·Filed 2009·Granted Nov 2, 2010·12 cites·20 claims
- 2092US7732572B2Cysteine variants of alpha interferon-2BOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Jun 8, 2010·22 cites·19 claims
- 2192US7629314B2Methods for making proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2004·Granted Dec 8, 2009·17 cites·23 claims
- 2292US7560101B2Method of treatment of an infection in an animal with GM-CSF cysteine muteins in the proximal region to helix ABOLDER BIOTECHNOLOGY INC·Filed 2006·Granted Jul 14, 2009·11 cites·15 claims
- 2391US7153943B2Derivatives of growth hormone and related proteins, and methods of use thereofBOLDER BIOTECHNOLOGY INC·Filed 2002·Granted Dec 26, 2006·29 cites·36 claims
- 2490US7947655B2Methods for making proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2009·Granted May 24, 2011·9 cites·4 claims
- 2588US10508131B2Cysteine analogs of exendin-4BOLDER BIOTECHNOLOGY INC·Filed 2017·Granted Dec 17, 2019·2 cites·14 claims
- 2687US7754855B1Immunoglobulin fusion proteinsBOLDER BIOTECHNOLOGY INC·Filed 2000·Granted Jul 13, 2010·24 cites·15 claims
- 2786US9296804B2NH2-terminal glutamine modified cysteine variants of interferon gammaBOLDER BIOTECHNOLOGY INC·Filed 2013·Granted Mar 29, 2016·2 cites·19 claims
- 2885US10016485B2Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposureBOLDER BIOTECHNOLOGY INC·Filed 2016·Granted Jul 10, 2018·2 cites·21 claims
- 2982US10653752B2Methods and use of growth hormone supergene family protein analogs for treatment of radiation exposureBOLDER BIOTECHNOLOGY INC·Filed 2018·Granted May 19, 2020·1 cites·20 claims
- 3077US9637530B2Methods of preparing cysteine variants of human recombinant IL-11BOLDER BIOTECHNOLOGY INC·Filed 2014·Granted May 2, 2017·1 cites·17 claims
- 3177US8859497B2Method of treatment using cysteine mutants of beta interferonBOLDER BIOTECHNOLOGY INC·Filed 2013·Granted Oct 14, 2014·1 cites·20 claims
- 3273US11229683B2Hematopoietic growth factor proteins and analogs thereof and angiotensin converting enzyme inhibitors for treatment of radiation exposureBOLDER BIOTECHNOLOGY INC·Filed 2016·Granted Jan 25, 2022·1 cites·12 claims
- 3373US2008076706A1Derivatives of Growth Hormone and Related Proteins, and Methods of Use ThereofBOLDER BIOTECHNOLOGY INC·Filed 2007·Application pending·0 cites
- 3473US2020283471A1Long acting proteins and peptides and methods of making and using the sameBOLDER BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 3569US10329337B2Method to increase the number of circulating platelets by administering PEGylated cysteine variants of IL-11BOLDER BIOTECHNOLOGY INC·Filed 2017·Granted Jun 25, 2019·0 cites·12 claims
- 3668US2014163204A1Derivatives of growth hormone and related proteinsBOLDER BIOTECHNOLOGY INC·Filed 2013·Application pending·0 cites
- 3763US12274736B2Hematopoietic growth factor proteins and analogs thereof and angiotensin converting enzyme inhibitors for treatment of radiation exposureBOLDER BIOTECHNOLOGY INC·Filed 2021·Granted Apr 15, 2025·0 cites·20 claims
- 3862US2009269804A1Methods for refolding proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2007·Application pending·0 cites
- 3961US2017015701A1Long acting proteins and peptides and methods of making and using the sameBOLDER BIOTECHNOLOGY INC·Filed 2016·Application pending·0 cites
- 4061US2017362626A1Methods for making proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2017·Application pending·0 cites
- 4161US2016244798A1Methods for making proteins containing free cysteine residuesBOLDER BIOTECHNOLOGY INC·Filed 2015·Application pending·0 cites
- 4249US2019270787A1Cysteine variants of interleukin-11 and methods of use thereofBOLDER BIOTECHNOLOGY INC·Filed 2019·Application pending·0 cites
- 4345US2009249503A1Enzyme conjugates for use as detoxifying agentsBOLDER BIOTECHNOLOGY INC·Filed 2005·Application pending·0 cites
- 4444US2010285014A1Immunoglobulin fusion proteinsBOLDER BIOTECHNOLOGY INC·Filed 2010·Application pending·0 cites
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