Assignee
CELTRIX PHARMA
US46 patents
Top patents by PatentIndex Score
US5824467AOct 20, 1998
Methods for predicting drug response
CELTRIX PHARMA155 citations99
US6087090AJul 11, 2000
Methods for predicting drug response
CELTRIX PHARMA89 citations98
US5571714ANov 5, 1996
Monoclonal antibodies which bind both transforming growth factors β1 and β2 and methods of use
CELTRIX PHARMA197 citations97
US5420243AMay 30, 1995
Biologically active TGF-β2 peptides
CELTRIX PHARMA42 citations96
US5393739AFeb 28, 1995
Use of bone morphogenetic protein in synergistic combination with TGF-β for bone repair
CELTRIX PHARMA150 citations96
US5118667AJun 2, 1992
Bone growth factors and inhibitors of bone resorption for promoting bone formation
CELTRIX PHARMA340 citations96
US5914254AJun 22, 1999
Expression of fusion polypeptides transported out of the cytoplasm without leader sequences
CELTRIX PHARMA118 citations95
US5563046AOct 8, 1996
Fusion polypeptides and proteins
CELTRIX PHARMA52 citations95
US5470727ANov 28, 1995
Chromosomal expression of non-bacterial genes in bacterial cells
CELTRIX PHARMA69 citations95
US5783185AJul 21, 1998
Monoclonal antibodies to transforming growth factor-beta and methods of use
CELTRIX PHARMA49 citations94
US5772998AJun 30, 1998
Monoclonal antibodies to transforming growth factor-beta and methods of use
CELTRIX PHARMA59 citations94
US5767079AJun 16, 1998
Method of treating ophthalmic disorders using TGF -β
CELTRIX PHARMA147 citations94
US5413989AMay 9, 1995
Method and activin compositions for inducing bone growth
CELTRIX PHARMA59 citations94
US5208219AMay 4, 1993
Method for inducing bone growth
CELTRIX PHARMA107 citations94
US6514937B1Feb 4, 2003
Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3
CELTRIX PHARMA24 citations92
US6040292AMar 21, 2000
Methods for treating diabetes
CELTRIX PHARMA43 citations92
US6025332AFeb 15, 2000
Method for treating low circulating levels of sex hormone steroids associated with aging using IGF or IGF/IGFBP-3
CELTRIX PHARMA16 citations92
US6025368AFeb 15, 2000
Method for treating the symptoms of chronic stress-related disorders using IGF
CELTRIX PHARMA29 citations91
US6015786AJan 18, 2000
Method for increasing sex steroid levels using IGF or IGF/IGFBP-3
CELTRIX PHARMA33 citations91
US5830706ANov 3, 1998
Polypeptide fusions to polypeptides of the beta-trefoil fold structural family
CELTRIX PHARMA21 citations91
US5723441AMar 3, 1998
Method of treating renal disease by administering IGF-I and IGFBP-3
CELTRIX PHARMA70 citations91
US5643867AJul 1, 1997
Method for treating catabolic conditions
CELTRIX PHARMA19 citations91
US5629172AMay 13, 1997
Expression of fusion polypeptides transported out of the cytoplasm without leader sequences
CELTRIX PHARMA20 citations91
US5407913AApr 18, 1995
Method and composition for systemic treatment of tissue injury
CELTRIX PHARMA50 citations91
US6436897B2Aug 20, 2002
Pharmaceutical formulations for IGF/IGFBP
CELTRIX PHARMA30 citations89
US6417330B1Jul 9, 2002
Insulin-like growth factor binding protein variants
CELTRIX PHARMA22 citations89
US5462925AOct 31, 1995
Transforming growth factor β2,3
CELTRIX PHARMA26 citations89
US5426098AJun 20, 1995
Increase in hematopoietic progenitor cells in peripheral blood by transforming growth factor beta
CELTRIX PHARMA29 citations89
US5914390AJun 22, 1999
Methods for increasing yields of recombinant proteins
CELTRIX PHARMA28 citations88
US5527776AJun 18, 1996
Treatment of immunologic and hematologic disorders with IGFBP alone or complexed with IGF
CELTRIX PHARMA22 citations88
US5681818AOct 28, 1997
Therapeutic uses of human somatomedin carrier proteins
CELTRIX PHARMA31 citations87
US5200509AApr 6, 1993
Human somatomedin carrier protein subunits and process for producing them; recombinant DNA molecules, hosts, processes and human somatomedin carrier protein-like polypeptides
CELTRIX PHARMA28 citations87
US6124259ASep 26, 2000
Method for treating ophthalmic disorders with IGFBP
CELTRIX PHARMA29 citations86
US5650396AJul 22, 1997
Methods of modulating inflammatory cytokines in the CNS using TGF-β
CELTRIX PHARMA22 citations85
US5670341ASep 23, 1997
DNA vectors, hosts, probes and recombinant methods of preparing human somatomedin-like carrier proteins or polypeptides
CELTRIX PHARMA14 citations77
US5624805AApr 29, 1997
Uses for antibodies which bind to human somatomedin carrier protein subunits
CELTRIX PHARMA12 citations77
US6518238B1Feb 11, 2003
Method of treating psychological and metabolic disorders using IGF or IGF/IGFBP-3
CELTRIX PHARMA4 citations74
US5658883AAug 19, 1997
Biologically active TGF-β1 peptides
CELTRIX PHARMA11 citations74
US5459051AOct 17, 1995
Methods and vectors for over-expression of ubiquitin fusion proteins in host cells
CELTRIX PHARMA12 citations74
USRE35694EDec 16, 1997
Polypeptide cartilage-inducing factors found in bone
CELTRIX PHARMA8 citations73
US5674843AOct 7, 1997
Increase in hematopoietic progenitor cells in peripheral blood by transforming growth factor β
CELTRIX PHARMA9 citations71
US5948757ASep 7, 1999
High dose IGF-1 therapy
CELTRIX PHARMA8 citations70
US6017885AJan 25, 2000
IGF/IGFBP complex for promoting bone formation and for regulating bone remodeling
CELTRIX PHARMA11 citations66
US5789547AAug 4, 1998
Method of producing insulin-like growth factor-I (IGF-I) and insulin-like growth factor binding protein-3 (IGFBP-3) with correct folding and disulfide bonding
CELTRIX PHARMA6 citations57
US7288516B1Oct 30, 2007
Null IGF for the treatment of cancer
CELTRIX PHARMA0 citations52
US5529982AJun 25, 1996
Inducing granulocyte production or B cell production in peripheral blood by TGF-β
CELTRIX PHARMA0 citations42