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GRAIL LLC

US31 patents

Top patents by PatentIndex Score

US11795513B2Oct 24, 2023

Methylation markers and targeted methylation probe panel

GRAIL LLC5 citations83
US11725251B2Aug 15, 2023

Methylation markers and targeted methylation probe panel

GRAIL LLC6 citations83
US11685958B2Jun 27, 2023

Methylation markers and targeted methylation probe panel

GRAIL LLC5 citations83
US11410750B2Aug 9, 2022

Methylation markers and targeted methylation probe panel

GRAIL LLC10 citations83
US11482303B2Oct 25, 2022

Convolutional neural network systems and methods for data classification

GRAIL LLC6 citations81
US12024750B2Jul 2, 2024

Methylation markers and targeted methylation probe panel

GRAIL LLC5 citations71
US11728007B2Aug 15, 2023

Methods and systems for analyzing nucleic acid sequences using mappability analysis and de novo sequence assembly

GRAIL LLC2 citations71
US11603553B2Mar 14, 2023

Methods of analyzing nucleic acid fragments

GRAIL LLC2 citations71
US11783915B2Oct 10, 2023

Convolutional neural network systems and methods for data classification

GRAIL LLC4 citations70
US11929148B2Mar 12, 2024

Systems and methods for enriching for cancer-derived fragments using fragment size

GRAIL LLC2 citations69
US11581062B2Feb 14, 2023

Systems and methods for classifying patients with respect to multiple cancer classes

GRAIL LLC2 citations67
US12234514B2Feb 25, 2025

Source of origin deconvolution based on methylation fragments in cell-free DNA samples

GRAIL LLC1 citations61
US11851650B2Dec 26, 2023

Enrichment of short nucleic acid fragments in sequencing library preparation

GRAIL LLC0 citations61
US12264364B2Apr 1, 2025

Methods of preparing dual-indexed DNA libraries for bisulfite conversion sequencing

GRAIL LLC0 citations60
US11869661B2Jan 9, 2024

Systems and methods for determining whether a subject has a cancer condition using transfer learning

GRAIL LLC2 citations60
US11680261B2Jun 20, 2023

Needle-based devices and methods for in vivo diagnostics of disease conditions

GRAIL LLC0 citations60
US11566284B2Jan 31, 2023

Methods of preparing dual-indexed DNA libraries for bisulfite conversion sequencing

GRAIL LLC0 citations60
US11447829B2Sep 20, 2022

Nucleic acid rearrangement and integration analysis

GRAIL LLC0 citations59
US12024797B2Jul 2, 2024

Methods of preparing and analyzing cell-free nucleic acid sequencing libraries

GRAIL LLC0 citations58
US11512349B2Nov 29, 2022

Methods for detecting disease using analysis of RNA

GRAIL LLC0 citations58
US12191000B2Jan 7, 2025

Systems and methods for classifying patients with respect to multiple cancer classes

GRAIL LLC0 citations57
US11180801B2Nov 23, 2021

Differential tagging of RNA for preparation of a cell-free DNA/RNA sequencing library

GRAIL LLC0 citations57
US12027237B2Jul 2, 2024

Anomalous fragment detection and classification

GRAIL LLC1 citations52
US11915797B2Feb 27, 2024

Methods for managing sequencing pileups

GRAIL LLC0 citations52
US11584958B2Feb 21, 2023

Library preparation and use thereof for sequencing based error correction and/or variant identification

GRAIL LLC0 citations49
US11884966B2Jan 30, 2024

Tissue-specific methylation marker

GRAIL LLC0 citations47
US11624064B2Apr 11, 2023

Enrichment of mutated cell free nucleic acids for cancer detection

GRAIL LLC0 citations47
US12073920B2Aug 27, 2024

Dynamically selecting sequencing subregions for cancer classification

GRAIL LLC0 citations45
US12236346B2Feb 25, 2025

Systems and methods for using a convolutional neural network to detect contamination

GRAIL LLC0 citations41
US12049672B2Jul 30, 2024

Methods and systems for screening for conditions

GRAIL LLC0 citations41
US11782957B2Oct 10, 2023

Systems and methods for automated classification of a document

GRAIL LLC0 citations35