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HELICOS BIOSCIENCES CORP

US23 patents

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US7279563B2Oct 9, 2007

Compounds for protecting hydroxyls and methods for their use

HELICOS BIOSCIENCES CORP157 citations99
US7482120B2Jan 27, 2009

Methods and compositions for improving fidelity in a nucleic acid synthesis reaction

HELICOS BIOSCIENCES CORP238 citations98
US7476734B2Jan 13, 2009

Nucleotide analogs

HELICOS BIOSCIENCES CORP66 citations98
US7282337B1Oct 16, 2007

Methods for increasing accuracy of nucleic acid sequencing

HELICOS BIOSCIENCES CORP610 citations98
US7220549B2May 22, 2007

Stabilizing a nucleic acid for nucleic acid sequencing

HELICOS BIOSCIENCES CORP203 citations98
US7169560B2Jan 30, 2007

Short cycle methods for sequencing polynucleotides

HELICOS BIOSCIENCES CORP841 citations98
US7956171B2Jun 7, 2011

Nucleotide analogs

HELICOS BIOSCIENCES CORP74 citations97
US7767400B2Aug 3, 2010

Paired-end reads in sequencing by synthesis

HELICOS BIOSCIENCES CORP78 citations97
US7666593B2Feb 23, 2010

Single molecule sequencing of captured nucleic acids

HELICOS BIOSCIENCES CORP218 citations96
US7424371B2Sep 9, 2008

Nucleic acid analysis

HELICOS BIOSCIENCES CORP143 citations96
US7276720B2Oct 2, 2007

Apparatus and methods for analyzing samples

HELICOS BIOSCIENCES CORP138 citations95
US7635562B2Dec 22, 2009

Methods and devices for nucleic acid sequence determination

HELICOS BIOSCIENCES CORP104 citations94
US7491498B2Feb 17, 2009

Short cycle methods for sequencing polynucleotides

HELICOS BIOSCIENCES CORP78 citations94
US7767805B2Aug 3, 2010

Methods and compositions for sequencing a nucleic acid

HELICOS BIOSCIENCES CORP27 citations92
US7678894B2Mar 16, 2010

Nucleotide analogs

HELICOS BIOSCIENCES CORP19 citations92
US7897345B2Mar 1, 2011

Short cycle methods for sequencing polynucleotides

HELICOS BIOSCIENCES CORP13 citations89
US7753095B2Jul 13, 2010

Storing and handling liquid reagents

HELICOS BIOSCIENCES CORP9 citations81
US7994304B2Aug 9, 2011

Methods and compositions for sequencing a nucleic acid

HELICOS BIOSCIENCES CORP18 citations80
US7593109B2Sep 22, 2009

Apparatus and methods for analyzing samples

HELICOS BIOSCIENCES CORP11 citations80
US7790391B2Sep 7, 2010

Methods of equalizing representation levels of nucleic acid targets

HELICOS BIOSCIENCES CORP16 citations77
US7397546B2Jul 8, 2008

Systems and methods for reducing detected intensity non-uniformity in a laser beam

HELICOS BIOSCIENCES CORP6 citations73
US8367377B2Feb 5, 2013

Methods and devices for nucleic acid sequence determination

HELICOS BIOSCIENCES CORP0 citations49
US7948625B2May 24, 2011

Apparatus and methods for analyzing samples

HELICOS BIOSCIENCES CORP0 citations48