Assignee
HOFFMANN LA ROCHE
US4,619 patents
Top patents by PatentIndex Score
US5641864AJun 24, 1997
Kits for high temperature reverse transcription of RNA
HOFFMANN LA ROCHE139 citations99
US5624833AApr 29, 1997
Purified thermostable nucleic acid polymerase enzyme from Thermotoga maritima
HOFFMANN LA ROCHE119 citations99
US5618703AApr 8, 1997
Unconventional nucleotide substitution in temperature selective RT-PCR
HOFFMANN LA ROCHE122 citations99
US5618711AApr 8, 1997
Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
HOFFMANN LA ROCHE301 citations99
US5602661AFeb 11, 1997
Optical component
HOFFMANN LA ROCHE410 citations99
US5539074AJul 23, 1996
Linear and cyclic polymers or oligomers having a photoreactive ethene group
HOFFMANN LA ROCHE139 citations99
US5487972AJan 30, 1996
Nucleic acid detection by the 5'-3'exonuclease activity of polymerases acting on adjacently hybridized oligonucleotides
HOFFMANN LA ROCHE855 citations99
US5407800AApr 18, 1995
Reverse transcription with Thermus thermophilus polymerase
HOFFMANN LA ROCHE167 citations99
US5374553ADec 20, 1994
DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima
HOFFMANN LA ROCHE306 citations99
US5319478AJun 7, 1994
Light control systems with a circular polarizer and a twisted nematic liquid crystal having a minimum path difference of λ/2
HOFFMANN LA ROCHE282 citations99
US5310652AMay 10, 1994
Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
HOFFMANN LA ROCHE386 citations99
US5292740AMar 8, 1994
Sulfonamides
HOFFMANN LA ROCHE180 citations99
US5210015AMay 11, 1993
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
HOFFMANN LA ROCHE2,135 citations99
US5196438AMar 23, 1993
Amino acid derivatives
HOFFMANN LA ROCHE181 citations99
US5142033AAug 25, 1992
Structure-independent DNA amplification by the polymerase chain reaction
HOFFMANN LA ROCHE169 citations99
US5037825AAug 6, 1991
Condensed heterocyclic compounds
HOFFMANN LA ROCHE170 citations99
US4892742AJan 9, 1990
Controlled release compositions with zero order release
HOFFMANN LA ROCHE163 citations99
US4614723ASep 30, 1986
Porphyrin derivatives as fluorescent markers for immunoassays
HOFFMANN LA ROCHE165 citations99
US4335120AJun 15, 1982
Administration of biologically active vitamin D3 and vitamin D2 materials
HOFFMANN LA ROCHE167 citations99
US4230701AOct 28, 1980
Administration of biologically active vitamin D3 and vitamin D2 materials
HOFFMANN LA ROCHE169 citations99
US7718666B2May 18, 2010
Pyrido [2,1-a] isoquinoline derivatives
HOFFMANN LA ROCHE62 citations98
US7563441B2Jul 21, 2009
Anti-P-selectin antibodies
HOFFMANN LA ROCHE94 citations98
US7375226B2May 20, 2008
Bi- and tricyclic substituted phenyl methanones
HOFFMANN LA ROCHE59 citations98
US7014866B2Mar 21, 2006
High dose solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate and process for making same
HOFFMANN LA ROCHE151 citations98
US6861440B2Mar 1, 2005
DPP IV inhibitors
HOFFMANN LA ROCHE116 citations98
US6756364B2Jun 29, 2004
Method of reducing gastrointestinal side effects associated with orlistat treatment
HOFFMANN LA ROCHE129 citations98
US6727261B2Apr 27, 2004
Pyrido[2,1-A]Isoquinoline derivatives
HOFFMANN LA ROCHE184 citations98
US6610830B1Aug 26, 2003
Microbial production of mature human leukocyte interferons
HOFFMANN LA ROCHE85 citations98
US6297375B1Oct 2, 2001
4-phenyl-pyridine derivatives
HOFFMANN LA ROCHE105 citations98
US5849860ADec 15, 1998
Polyethylene-protein conjugates
HOFFMANN LA ROCHE221 citations98
US5834594ANov 10, 1998
Polyethylene-protein conjugates
HOFFMANN LA ROCHE262 citations98
US5792834AAug 11, 1998
Polyethylene-protein conjugates
HOFFMANN LA ROCHE129 citations98
US5747646AMay 5, 1998
Polyethylene-protein conjugates
HOFFMANN LA ROCHE300 citations98
US5705062AJan 6, 1998
Analytical device for separating magnetic microparticles from suspensions
HOFFMANN LA ROCHE224 citations98
US5604099AFeb 18, 1997
Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
HOFFMANN LA ROCHE201 citations98
US5567349AOct 22, 1996
Photo cross-linkable liquid crystals
HOFFMANN LA ROCHE109 citations98
US5559213ASep 24, 1996
Polyethylene-protein conjugates
HOFFMANN LA ROCHE204 citations98
US5539063AJul 23, 1996
Polymer for making poly(ethylene glycol)-protein conjugates
HOFFMANN LA ROCHE106 citations98
US5527669AJun 18, 1996
Methods, primers and probes for detection of hepatitis C and novel variants
HOFFMANN LA ROCHE143 citations98
US5476774ADec 19, 1995
Quantitation of nucleic acids using the polymerase chain reaction
HOFFMANN LA ROCHE210 citations98
US5468613ANov 21, 1995
Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
HOFFMANN LA ROCHE331 citations98
US5466591ANov 14, 1995
5' to 3' exonuclease mutations of thermostable DNA polymerases
HOFFMANN LA ROCHE229 citations98
US5455170AOct 3, 1995
Mutated thermostable nucleic acid polymerase enzyme from Thermus species Z05
HOFFMANN LA ROCHE136 citations98
US5455178AOct 3, 1995
Microoptical sensor and method
HOFFMANN LA ROCHE294 citations98
US5420129AMay 30, 1995
Phenylsulfonylamide pyrimidine
HOFFMANN LA ROCHE132 citations98
US5418149AMay 23, 1995
Reduction of non-specific amplification glycosylase using DUTP and DNA uracil
HOFFMANN LA ROCHE399 citations98
US5333675AAug 2, 1994
Apparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling steps
HOFFMANN LA ROCHE465 citations98
US5219727AJun 15, 1993
Quantitation of nucleic acids using the polymerase chain reaction
HOFFMANN LA ROCHE340 citations98
US5157041AOct 20, 1992
Amino acid derivatives
HOFFMANN LA ROCHE117 citations98
US4512924AApr 23, 1985
Pyridazo[1,2-a][1,2]diazepines
HOFFMANN LA ROCHE147 citations98
Showing the top 50 of 4,619 patents by PatentIndex Score.