Assignee

INTERX RESEARCH CORP

76 patents

Top patents by PatentIndex Score

US4260769AApr 7, 1981

5,5-Diphenylhydantoins

INTERX RESEARCH CORP69 citations96

US4221787ASep 9, 1980

Esteramide prodrugs of anti-inflammatory corticosteroids

INTERX RESEARCH CORP78 citations96

US4160099AJul 3, 1979

Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives

INTERX RESEARCH CORP60 citations96

US4061753ADec 6, 1977

Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease

INTERX RESEARCH CORP114 citations96

US4462991AJul 31, 1984

Method of increasing oral absorption of polar bioactive agents

INTERX RESEARCH CORP106 citations95

US4158005AJun 12, 1979

Intermediates useful in the synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols

INTERX RESEARCH CORP107 citations94

US4252790AFeb 24, 1981

Method for treating gastric ulcer-prone patients

INTERX RESEARCH CORP31 citations93

US4727151AFeb 23, 1988

Labile quaternary ammonium salts as prodrugs

INTERX RESEARCH CORP32 citations92

US4470980ASep 11, 1984

Method of increasing oral absorption of β-lactam antibiotics

INTERX RESEARCH CORP32 citations92

US4311706AJan 19, 1982

Novel dopa/dopamine prodrugs

INTERX RESEARCH CORP51 citations92

US4204065AMay 20, 1980

Soft quaternary surface active agents and method of using same

INTERX RESEARCH CORP39 citations92

US4000293ADec 28, 1976

Method of inhibiting bacterial growth with certain selected 3-chloro-2-oxazolidinones

INTERX RESEARCH CORP34 citations92

US3931213AJan 6, 1976

3-Chloro-2-oxazolidinones

INTERX RESEARCH CORP41 citations92

US4147768AApr 3, 1979

Enteric coated digoxin and therapeutic use thereof

INTERX RESEARCH CORP45 citations87

US3961041AJun 1, 1976

Effervescent enteric coated L-dopa formulation and method of using the same

INTERX RESEARCH CORP55 citations87

US4275064AJun 23, 1981

Transient pro-drug forms of xanthine derivatives and their use as topical anti-inflammatory agents

INTERX RESEARCH CORP24 citations82

US4213978AJul 22, 1980

Anti-acne and anti-seborrhea prodrug derivatives of progesterone

INTERX RESEARCH CORP27 citations82

US4206220AJun 3, 1980

Prodrugs for the improved delivery of non-steroidal anti-inflammatory agents

INTERX RESEARCH CORP28 citations82

US4163058AJul 31, 1979

Derivatives of 5,5-diphenylhydantoin exhibiting enhanced solubility and the therapeutic use thereof

INTERX RESEARCH CORP28 citations82

US4065566ADec 27, 1977

N-Nicotinoyl-3,4-dinicotinoyloxy-L-phenylalanine and derivatives pharmaceutical compositions and methods containing same

INTERX RESEARCH CORP19 citations82

US4061722ADec 6, 1977

Selected quaternary ammonium salts of pilocarpine useful in reducing intraocular pressure in warm-blooded animals

INTERX RESEARCH CORP26 citations82

US3998815ADec 21, 1976

1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

INTERX RESEARCH CORP17 citations82

US3962447AJun 8, 1976

Novel pro-drug derivatives of pyridinium aldoxime type cholinesterase reactivators and method of using same

INTERX RESEARCH CORP24 citations82

US4412994ANov 1, 1983

Mannich-base hydroxamic acid prodrugs, compositions and use

INTERX RESEARCH CORP26 citations76

US4340603AJul 20, 1982

Novel inotropic prodrugs

INTERX RESEARCH CORP8 citations74

US4285947AAug 25, 1981

Aldehyde adducts of triamterene

INTERX RESEARCH CORP8 citations74

US4145441AMar 20, 1979

Sympathomimetic amines exhibiting anti-hemorrhoidal activity

INTERX RESEARCH CORP16 citations74

US4094983AJun 13, 1978

Method for reducing intraocular pressure in warm-blooded animals

INTERX RESEARCH CORP14 citations74

US4069322AJan 17, 1978

Pro-drugs for the improved delivery of certain selected anti-inflammatory steroids

INTERX RESEARCH CORP10 citations74

US4045578AAug 30, 1977

N-chloro-amino acid derivatives exhibiting antibacterial activity

INTERX RESEARCH CORP13 citations74

US4021546AMay 3, 1977

Pro-drug forms of digoxin and method of preparing and using same

INTERX RESEARCH CORP8 citations74

US3989711ANov 2, 1976

Soft quaternary surface active agents exhibiting antibacterial activity

INTERX RESEARCH CORP14 citations74

US3966796AJun 29, 1976

N-chloro-amino acid derivatives activity

INTERX RESEARCH CORP13 citations74

US3957803AMay 18, 1976

Certain transient pro-drug forms of phenylbutazone

INTERX RESEARCH CORP9 citations74

US4246399AJan 20, 1981

Complexes of doxorubicin exhibiting enhanced stability

INTERX RESEARCH CORP6 citations73

US4085214AApr 18, 1978

Stable pro-drug forms of theophylline

INTERX RESEARCH CORP8 citations73

US3950521AApr 13, 1976

Administration of alkali metal salicylamide salts

INTERX RESEARCH CORP6 citations73

US3935196AJan 27, 1976

Useful pro-drug forms of theophylline

INTERX RESEARCH CORP7 citations73

US4088783AMay 9, 1978

Novel optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols and the pharmaceutically acceptable acid addition salts thereof

INTERX RESEARCH CORP6 citations72

US4035405AJul 12, 1977

Novel synthesis for preparing the hydrochloride salt of selected catecholamine derivatives

INTERX RESEARCH CORP9 citations72

US3966749AJun 29, 1976

Novel synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols, the pharmaceutically acceptable acid addition salts thereof and intermediate useful in the preparation thereof

INTERX RESEARCH CORP8 citations72

US4275219AJun 23, 1981

Novel process and intermediates useful in the preparation of sympathomimetic amines

INTERX RESEARCH CORP7 citations71

US3959485AMay 25, 1976

Method of reducing intraocular pressure in warm-blooded animals

INTERX RESEARCH CORP11 citations69

US4178376ADec 11, 1979

Method for inducing rapid therapeutically effective antimalarial levels of certain selected conventional antimalarials

INTERX RESEARCH CORP10 citations66

US4313956AFeb 2, 1982

Novel sypathomimetic amine prodrugs

INTERX RESEARCH CORP6 citations63

US4268441AMay 19, 1981

Prodrugs for improved bioavailability of certain Δ4 -3-ketosteroidal sex hormones

INTERX RESEARCH CORP2 citations63

US4263305AApr 21, 1981

Novel pyridiniumaldoximes having micellar characteristics

INTERX RESEARCH CORP5 citations63

Showing the top 50 of 76 patents by PatentIndex Score.

INTERX RESEARCH CORP

Top patents by PatentIndex Score

5,5-Diphenylhydantoins

Esteramide prodrugs of anti-inflammatory corticosteroids

Labile, non-heterocyclic quaternary ammonium salt/esters as transient derivatives

Treating psoriasis with transient pro-drug forms of xanthine derivatives

Novel, transient pro-drug forms of L-DOPA to treat Parkinson&#39;s disease

Novel, transient pro-drug forms of l-dopa

Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson&#39;s disease

Method of increasing oral absorption of polar bioactive agents

Intermediates useful in the synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols

Method for treating gastric ulcer-prone patients

Labile quaternary ammonium salts as prodrugs

Method of increasing oral absorption of β-lactam antibiotics

Novel dopa/dopamine prodrugs

Soft quaternary surface active agents and method of using same

Method of inhibiting bacterial growth with certain selected 3-chloro-2-oxazolidinones

3-Chloro-2-oxazolidinones

Enteric coated digoxin and therapeutic use thereof

Effervescent enteric coated L-dopa formulation and method of using the same

Transient pro-drug forms of xanthine derivatives and their use as topical anti-inflammatory agents

Anti-acne and anti-seborrhea prodrug derivatives of progesterone

Prodrugs for the improved delivery of non-steroidal anti-inflammatory agents

Derivatives of 5,5-diphenylhydantoin exhibiting enhanced solubility and the therapeutic use thereof

N-Nicotinoyl-3,4-dinicotinoyloxy-L-phenylalanine and derivatives pharmaceutical compositions and methods containing same

Selected quaternary ammonium salts of pilocarpine useful in reducing intraocular pressure in warm-blooded animals

1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

Novel pro-drug derivatives of pyridinium aldoxime type cholinesterase reactivators and method of using same

Mannich-base hydroxamic acid prodrugs, compositions and use

Novel inotropic prodrugs

Aldehyde adducts of triamterene

Sympathomimetic amines exhibiting anti-hemorrhoidal activity

Method for reducing intraocular pressure in warm-blooded animals

Pro-drugs for the improved delivery of certain selected anti-inflammatory steroids

N-chloro-amino acid derivatives exhibiting antibacterial activity

Pro-drug forms of digoxin and method of preparing and using same

Soft quaternary surface active agents exhibiting antibacterial activity

N-chloro-amino acid derivatives activity

Certain transient pro-drug forms of phenylbutazone

Complexes of doxorubicin exhibiting enhanced stability

Stable pro-drug forms of theophylline

Administration of alkali metal salicylamide salts

Useful pro-drug forms of theophylline

Novel optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols and the pharmaceutically acceptable acid addition salts thereof

Novel synthesis for preparing the hydrochloride salt of selected catecholamine derivatives

Novel synthesis of optically active m-acyloxy-α-[(methylamino)methyl]benzyl alcohols, the pharmaceutically acceptable acid addition salts thereof and intermediate useful in the preparation thereof

Novel process and intermediates useful in the preparation of sympathomimetic amines

Method of reducing intraocular pressure in warm-blooded animals

Method for inducing rapid therapeutically effective antimalarial levels of certain selected conventional antimalarials

Novel sypathomimetic amine prodrugs

Prodrugs for improved bioavailability of certain Δ4 -3-ketosteroidal sex hormones

Novel pyridiniumaldoximes having micellar characteristics

Novel, transient pro-drug forms of L-DOPA to treat Parkinson's disease

Novel, transient pro-drug forms of l-dopa useful in the treatment of parkinson's disease