Assignee
LEXICON PHARMACEUTICALS INC
US·49 granted patents·28 pending applications·371 citations·filing 2000–2025
Top patents by PatentIndex Score
77 records- 0195US7935796B2Monoclonal antibodies against ANGPTL3LEXICON PHARMACEUTICALS INC·Filed 2007·Granted May 3, 2011·74 cites·19 claims
- 0295US7553840B24-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2007·Granted Jun 30, 2009·46 cites·24 claims
- 0393US7781577B2Inhibitors of sodium glucose co-transporter 2 and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2007·Granted Aug 24, 2010·18 cites·27 claims
- 0493US7709493B24-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compounds and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2009·Granted May 4, 2010·25 cites·20 claims
- 0592US7649098B2Imidazole-based compounds, compositions comprising them and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2007·Granted Jan 19, 2010·20 cites·15 claims
- 0691US7846945B2Piperdine-based inhibitors of sodium glucose co-transporter 2 and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Dec 7, 2010·10 cites·33 claims
- 0791US7723345B2Multicyclic amino acid derivatives and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2006·Granted May 25, 2010·23 cites·8 claims
- 0890US7312079B1Variants of FAM3CLEXICON PHARMACEUTICALS INC·Filed 2006·Granted Dec 25, 2007·13 cites·4 claims
- 0987US10106569B2Inhibitors of sodium glucose transporter 1 for constipationLEXICON PHARMACEUTICALS INC·Filed 2017·Granted Oct 23, 2018·5 cites·1 claims
- 1087US9688710B2Inhibitors of sodium glucose cotransporter 1LEXICON PHARMACEUTICALS INC·Filed 2015·Granted Jun 27, 2017·5 cites·8 claims
- 1187US7655762B2Monoclonal antibodies against ANGPTL4LEXICON PHARMACEUTICALS INC·Filed 2006·Granted Feb 2, 2010·8 cites·4 claims
- 1286US9403832B2Pyrazolo[1,5-a]pyrimidine-based compounds, compositions comprising them, and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2014·Granted Aug 2, 2016·9 cites·6 claims
- 1386US8026347B2Methods and compounds useful for the preparation of sodium glucose co-transporter 2 inhibitorsLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Sep 27, 2011·9 cites·42 claims
- 1486US7968729B21-phenyl-1H-pyrazole-based compoundsLEXICON PHARMACEUTICALS INC·Filed 2010·Granted Jun 28, 2011·4 cites·8 claims
- 1586US7968559B2Methods of using 4-phenyl-6-(2,2,2-trifluoro-1-phenylethoxy)pyrimidine-based compoundsLEXICON PHARMACEUTICALS INC·Filed 2010·Granted Jun 28, 2011·8 cites·29 claims
- 1685US9200025B2Inhibitors of sodium glucose cotransporter 1LEXICON PHARMACEUTICALS INC·Filed 2013·Granted Dec 1, 2015·7 cites·15 claims
- 1785US7897763B2Process for the preparation of substituted phenylalaninesLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Mar 1, 2011·3 cites·2 claims
- 1885US7812174B2Methods of preparing imidazole-based compoundsLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Oct 12, 2010·7 cites·28 claims
- 1984US7825142B2Heterocyclic compounds, compositions comprising them and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2009·Granted Nov 2, 2010·6 cites·10 claims
- 2084US7598280B2Heterocyclic compounds, compositions comprising them and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Oct 6, 2009·6 cites·2 claims
- 2184US7423043B24-Piperidin-1-yl-7H-pyrrolo[2,3-d]pyrimidine compoundsLEXICON PHARMACEUTICALS INC·Filed 2006·Granted Sep 9, 2008·7 cites·18 claims
- 2283US7875622B2Methods and compositions for treating pulmonary hypertension and related diseases and disordersLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Jan 25, 2011·4 cites·16 claims
- 2383US7855291B2Process for the preparation of substituted phenylalaninesLEXICON PHARMACEUTICALS INC·Filed 2006·Granted Dec 21, 2010·4 cites·10 claims
- 2481US7951941B2Process for preparing 5-alkyl-7H-pyrrolo[2,3-d] pyrimindine-2-olsLEXICON PHARMACEUTICALS INC·Filed 2007·Granted May 31, 2011·3 cites·32 claims
- 2581US6951946B2Large scale synthesis of 1,2,4- and 1,3,4-oxadiazole carboxylatesLEXICON PHARMACEUTICALS INC·Filed 2003·Granted Oct 4, 2005·9 cites·26 claims
- 2680US7825150B2Compositions and methods for treating immunological and inflammatory diseases and disordersLEXICON PHARMACEUTICALS INC·Filed 2008·Granted Nov 2, 2010·8 cites·13 claims
- 2779US12312325B2Methods and compounds useful in the synthesis of an AAK1 inhibitorLEXICON PHARMACEUTICALS INC·Filed 2023·Granted May 27, 2025·0 cites·16 claims
- 2879US9682982B2Inhibitors of adapter associated kinase 1, compositions comprising them, and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2015·Granted Jun 20, 2017·3 cites·10 claims
- 2979US2023218650A1Compositions comprising and methods of using inhibitors of sodium-glucose cotransporters 1 and 2LEXICON PHARMACEUTICALS INC·Filed 2023·Application pending·0 cites
- 3077US10968192B2Crystalline solid forms of N-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oxopropan-2-yl)-4-(4-(2-methyl-5-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2H-pyran-2-yl)benzyl)phenyl)butanamide and methods of their synthesisLEXICON PHARMACEUTICALS INC·Filed 2019·Granted Apr 6, 2021·1 cites·5 claims
- 3177US7268222B1Polynucleotides encoding human transporter proteinsLEXICON PHARMACEUTICALS INC·Filed 2000·Granted Sep 11, 2007·11 cites·4 claims
- 3277US2025346570A1Solid forms of (s)-1-((2',6-bis(difluoromethyl)-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2025·Application pending·0 cites
- 3375US2024226125A1Use of sotagliflozin for the treatment of patients with type 1 diabetes mellitusLEXICON PHARMACEUTICALS INC·Filed 2024·Application pending·0 cites
- 3474US7300949B2Thiazolopyrazoles and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2005·Granted Nov 27, 2007·2 cites·18 claims
- 3573US12344596B2Solid forms of (S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine and salts thereofLEXICON PHARMACEUTICALS INC·Filed 2023·Granted Jul 1, 2025·0 cites·11 claims
- 3672US2025282747A1Methods and compounds useful in the synthesis of an aak1 inhibitorLEXICON PHARMACEUTICALS INC·Filed 2025·Application pending·0 cites
- 3771US6713514B1PPAR-γ agonists as agents for the treatment of type II diabetesLEXICON PHARMACEUTICALS INC·Filed 2000·Granted Mar 30, 2004·5 cites·7 claims
- 3867US2025170157A1Methods and compositions for the treatment of hepatic encephalopathyLEXICON PHARMACEUTICALS INC·Filed 2024·Application pending·0 cites
- 3965US7402730B1Knockout animals manifesting hyperlipidemiaLEXICON PHARMACEUTICALS INC·Filed 2006·Granted Jul 22, 2008·2 cites·2 claims
- 4065US6642390B2One step synthesis of 1,2,3-triazole carboxylic acidsLEXICON PHARMACEUTICALS INC·Filed 2002·Granted Nov 4, 2003·3 cites·13 claims
- 4165US2021038626A1Compositions comprising and methods of using inhibitors of sodium-glucose cotransporters 1 and 2LEXICON PHARMACEUTICALS INC·Filed 2020·Application pending·0 cites
- 4264US2025108032A1Methods of treating type 1 diabetes and kidney diseaseLEXICON PHARMACEUTICALS INC·Filed 2024·Application pending·0 cites
- 4364US2022088048A1Use of sotagliflozin for the treatment of patients with type 1 diabetes mellitusLEXICON PHARMACEUTICALS INC·Filed 2021·Application pending·0 cites
- 4462US2019099436A1Sodium glucose co-transporter inhibitors and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2018·Application pending·0 cites
- 4561US11059907B2Antibodies that bind Notum PectinacetylesteraseLEXICON PHARMACEUTICALS INC·Filed 2019·Granted Jul 13, 2021·0 cites·13 claims
- 4661US2025114323A1Methods of reducing the risk of cardiovascular events in patients with left ventricular hypertrophyLEXICON PHARMACEUTICALS INC·Filed 2024·Application pending·0 cites
- 4760US7998994B2Solid forms of (1R,2S,3R)-1-(2-(isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol and methods of their useLEXICON PHARMACEUTICALS INC·Filed 2009·Granted Aug 16, 2011·0 cites·8 claims
- 4860US7374932B2Human kinases and polynucleotides encoding the same, and uses thereofLEXICON PHARMACEUTICALS INC·Filed 2004·Granted May 20, 2008·1 cites·5 claims
- 4958US2021038627A1Use of sotagliflozin for the treatment of patients with type 1 diabetes mellitusLEXICON PHARMACEUTICALS INC·Filed 2020·Application pending·0 cites
- 5058US2009149336A1Indexed library of cells containing genomic modifications and methods of making and utilizing the sameLEXICON PHARMACEUTICALS INC·Filed 2007·Application pending·0 cites
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