Assignee
MANOHARAN MUTHIAH
US31 patents
Top patents by PatentIndex Score
US9186325B2Nov 17, 2015
Lipids and compositions for the delivery of therapeutics
MANOHARAN MUTHIAH100 citations99
US8999351B2Apr 7, 2015
Lipids and compositions for the delivery of therapeutics
MANOHARAN MUTHIAH102 citations99
US8927513B2Jan 6, 2015
5′ phosphate mimics
MANOHARAN MUTHIAH108 citations99
US8883202B2Nov 11, 2014
Lipid compositions
MANOHARAN MUTHIAH104 citations99
US8642076B2Feb 4, 2014
Lipid containing formulations
MANOHARAN MUTHIAH155 citations99
US8450467B2May 28, 2013
Carbohydrate conjugates as delivery agents for oligonucleotides
MANOHARAN MUTHIAH227 citations99
US8110674B2Feb 7, 2012
Therapeutic compositions
MANOHARAN MUTHIAH81 citations99
US8106022B2Jan 31, 2012
Carbohydrate conjugates as delivery agents for oligonucleotides
MANOHARAN MUTHIAH588 citations99
US8575123B2Nov 5, 2013
Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components
MANOHARAN MUTHIAH82 citations98
US8404862B2Mar 26, 2013
Ligand-conjugated monomers
MANOHARAN MUTHIAH84 citations98
US9012498B2Apr 21, 2015
Biodegradable lipids for the delivery of active agents
MANOHARAN MUTHIAH104 citations97
US9220683B2Dec 29, 2015
Lipids and compositions for the delivery of therapeutics
MANOHARAN MUTHIAH28 citations96
US8722082B2May 13, 2014
Lipids and compositions for the delivery of therapeutics
MANOHARAN MUTHIAH44 citations94
US9687550B2Jun 27, 2017
Compositions for nucleic acid delivery
MANOHARAN MUTHIAH21 citations93
US8975389B2Mar 10, 2015
Nucleic acid chemical modifications
MANOHARAN MUTHIAH31 citations93
US8754201B2Jun 17, 2014
Therapeutic compositions
MANOHARAN MUTHIAH8 citations93
US8420799B2Apr 16, 2013
Therapeutic compositions
MANOHARAN MUTHIAH11 citations93
US8507455B2Aug 13, 2013
Folate conjugates
MANOHARAN MUTHIAH32 citations92
US8507661B2Aug 13, 2013
Modified iRNA agents
MANOHARAN MUTHIAH25 citations92
US8962580B2Feb 24, 2015
Chemical modifications of monomers and oligonucleotides with cycloaddition
MANOHARAN MUTHIAH26 citations91
US8431693B2Apr 30, 2013
Process for desilylation of oligonucleotides
MANOHARAN MUTHIAH15 citations90
US9725479B2Aug 8, 2017
5′-end derivatives
MANOHARAN MUTHIAH12 citations84
US8426377B2Apr 23, 2013
iRNA agents with biocleavable tethers
MANOHARAN MUTHIAH10 citations84
US9198972B2Dec 1, 2015
Monomers and oligonucleotides comprising cycloaddition adduct(s)
MANOHARAN MUTHIAH10 citations83
US8445665B2May 21, 2013
Therapeutic compositions
MANOHARAN MUTHIAH3 citations74
US10913767B2Feb 9, 2021
Oligonucleotides comprising acyclic and abasic nucleosides and analogs
MANOHARAN MUTHIAH4 citations73
US9512164B2Dec 6, 2016
Oligonucleotide end caps
MANOHARAN MUTHIAH4 citations73
US9254327B2Feb 9, 2016
Methods and compositions for delivery of active agents
MANOHARAN MUTHIAH2 citations63
US8470988B2Jun 25, 2013
Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety
MANOHARAN MUTHIAH3 citations63
US8063198B2Nov 22, 2011
Processes and reagents for desilylation of oligonucleotides
MANOHARAN MUTHIAH0 citations52
US8058448B2Nov 15, 2011
Processes and reagents for sulfurization of oligonucleotides
MANOHARAN MUTHIAH0 citations52