Assignee
MASSACHUSETTS GEN HOSPITAL
US·1,054 granted patents·778 pending applications·8,367 citations·filing 1975–2025
Top patents by PatentIndex Score
1,832 records- 0199US9812846B2Method and apparatus for performing optical imaging using frequency-domain interferometryMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Nov 7, 2017·34 cites·39 claims
- 0299US9513276B2Method and apparatus for optical imaging via spectral encodingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Dec 6, 2016·50 cites·21 claims
- 0399US7569620B2High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the meltMASSACHUSETTS GEN HOSPITAL·Filed 2007·Granted Aug 4, 2009·41 cites·25 claims
- 0499US4036945AComposition and method for determining the size and location of myocardial infarctsMASSACHUSETTS GEN HOSPITAL·Filed 1976·Granted Jul 19, 1977·646 cites·6 claims
- 0598US11944971B2Sorting particles in a microfluidic deviceMASSACHUSETTS GEN HOSPITAL·Filed 2021·Granted Apr 2, 2024·4 cites·18 claims
- 0698US11168338B2RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic lociMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted Nov 9, 2021·17 cites·10 claims
- 0798US11098326B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted Aug 24, 2021·16 cites·14 claims
- 0898US11013686B2Cromolyn compositions and methods thereofMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted May 25, 2021·7 cites·29 claims
- 0998US11007503B2Systems and methods for a cooled nitric oxide generatorMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted May 18, 2021·16 cites·12 claims
- 1098US10844403B2Increasing specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Nov 24, 2020·31 cites·30 claims
- 1198US10544433B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jan 28, 2020·34 cites·10 claims
- 1298US10526591B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jan 7, 2020·19 cites·32 claims
- 1398US10299720B2Reversal of general anesthesia by administration of methylphenidate, amphetamine, modafinil, amantadine, and/or caffeineMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted May 28, 2019·451 cites·10 claims
- 1498US10239038B2Systems and methods for a cooled nitric oxide generatorMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Mar 26, 2019·22 cites·44 claims
- 1598US10138476B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Nov 27, 2018·35 cites·28 claims
- 1698US10093910B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Oct 9, 2018·26 cites·30 claims
- 1798US10058530B2Combination therapies for the treatment of Alzheimer's disease and related disordersMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Aug 28, 2018·19 cites·14 claims
- 1898US9968618B1Combination therapies for the treatment of Alzheimer's disease and related disordersMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted May 15, 2018·19 cites·18 claims
- 1998US9956562B2Devices and method for enrichment and alteration of cells and other particlesMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted May 1, 2018·18 cites·26 claims
- 2098US9944912B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Apr 17, 2018·25 cites·33 claims
- 2198US9926546B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Mar 27, 2018·52 cites·32 claims
- 2298US9895694B2Sorting particles in a microfluidic deviceMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted Feb 20, 2018·24 cites·8 claims
- 2398US9885033B2Increasing specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Feb 6, 2018·95 cites·3 claims
- 2498US9752132B2Engineered CRISPR-CAS9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Sep 5, 2017·48 cites·24 claims
- 2598US9610582B2Combined sorting and concentrating particles in a microfluidic deviceMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted Apr 4, 2017·24 cites·26 claims
- 2698US9567603B2Using RNA-guided FokI nucleases (RFNs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Feb 14, 2017·86 cites·10 claims
- 2798US9512446B1Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Dec 6, 2016·164 cites·27 claims
- 2898US7304097B2High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the meltMASSACHUSETTS GEN HOSPITAL·Filed 2006·Granted Dec 4, 2007·42 cites·44 claims
- 2998US6214553B1Libraries of protein encoding RNA-protein fusionsMASSACHUSETTS GEN HOSPITAL·Filed 1999·Granted Apr 10, 2001·283 cites·17 claims
- 3097US12241096B2Engineered CRISPR-Cas9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2023·Granted Mar 4, 2025·4 cites·25 claims
- 3197US11944972B2Concentrating particles in a microfluidic deviceMASSACHUSETTS GEN HOSPITAL·Filed 2021·Granted Apr 2, 2024·2 cites·10 claims
- 3297US11920152B2Increasing specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2020·Granted Mar 5, 2024·4 cites·9 claims
- 3397US11110097B2Combination therapies for the treatment of alzheimer's disease and related disordersMASSACHUSETTS GEN HOSPITAL·Filed 2019·Granted Sep 7, 2021·7 cites·22 claims
- 3497US11052393B2Concentrating particles in a microfluidic deviceMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Jul 6, 2021·7 cites·14 claims
- 3597US10760064B2RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic lociMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Sep 1, 2020·38 cites·20 claims
- 3697US10633642B2Engineered CRISPR-Cas9 nucleasesMASSACHUSETTS GEN HOSPITAL·Filed 2018·Granted Apr 28, 2020·12 cites·27 claims
- 3797US10415059B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2017·Granted Sep 17, 2019·43 cites·31 claims
- 3897US10378027B2RNA-guided targeting of genetic and epigenomic regulatory proteins to specific genomic lociMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Aug 13, 2019·18 cites·11 claims
- 3997US10150116B2Concentrating particles in a microfluidic deviceMASSACHUSETTS GEN HOSPITAL·Filed 2015·Granted Dec 11, 2018·13 cites·23 claims
- 4097US10119133B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Nov 6, 2018·39 cites·11 claims
- 4197US10068740B2Distributed, field emission-based X-ray source for phase contrast imagingMASSACHUSETTS GEN HOSPITAL·Filed 2013·Granted Sep 4, 2018·31 cites·5 claims
- 4297US9926545B2Engineered CRISPR-CAS9 nucleases with altered PAM specificityMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Mar 27, 2018·18 cites·33 claims
- 4397US9918992B2Combination therapies for the treatment of Alzheimer's disease and related disordersMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Mar 20, 2018·18 cites·6 claims
- 4497US9913847B2Combination therapies for the treatment of alzheimer's disease and related disordersMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Mar 13, 2018·19 cites·14 claims
- 4597US9855276B2Combination therapies for the treatment of Alzheimer's disease and related disordersMASSACHUSETTS GEN HOSPITAL·Filed 2013·Granted Jan 2, 2018·32 cites·14 claims
- 4697US9850484B2Comprehensive in vitro reporting of cleavage events by sequencing (Circle-seq)MASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Dec 26, 2017·19 cites·19 claims
- 4797US9808803B2Systems and methods for particle focusing in microchannelsMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Nov 7, 2017·15 cites·6 claims
- 4897US9649220B2Treatment systems for removing heat from subcutaneous lipid-rich cellsMASSACHUSETTS GEN HOSPITAL·Filed 2013·Granted May 16, 2017·72 cites·14 claims
- 4997US9567604B2Using truncated guide RNAs (tru-gRNAs) to increase specificity for RNA-guided genome editingMASSACHUSETTS GEN HOSPITAL·Filed 2014·Granted Feb 14, 2017·87 cites·17 claims
- 5097US9549773B2Method and apparatus for dermatological hypopigmentationMASSACHUSETTS GEN HOSPITAL·Filed 2016·Granted Jan 24, 2017·30 cites·18 claims
Showing the top 50 of 1,832 patent records by PatentIndex Score.
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