Assignee
MOLECULAR TEMPLATES INC
US·24 granted patents·33 pending applications·99 citations·filing 1998–2024
Top patents by PatentIndex Score
57 records- 0197US11857628B2Shiga toxin A subunit effector polypeptides, Shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugationMOLECULAR TEMPLATES INC·Filed 2021·Granted Jan 2, 2024·4 cites·22 claims
- 0297US11389542B1Shiga toxin a subunit effector polypeptides, Shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugationMOLECULAR TEMPLATES INC·Filed 2021·Granted Jul 19, 2022·5 cites·10 claims
- 0397US11312751B2MHC class I epitope delivering polypeptidesMOLECULAR TEMPLATES INC·Filed 2021·Granted Apr 26, 2022·6 cites·3 claims
- 0496US11225509B2HER2-targeting molecules comprising de-immunized, Shiga toxin A subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2020·Granted Jan 18, 2022·4 cites·6 claims
- 0595US10815469B2Cell-targeting molecules comprising protease-cleavage resistant, Shiga toxin A subunit effector polypeptides and carboxy-terminal moietiesMOLECULAR TEMPLATES INC·Filed 2015·Granted Oct 27, 2020·22 cites·40 claims
- 0694US11365223B2De-immunized, Shiga toxin a subunit scaffolds and cell-targeting molecules comprising the sameMOLECULAR TEMPLATES INC·Filed 2021·Granted Jun 21, 2022·7 cites·14 claims
- 0794US11136395B2PD-L1 -binding molecules comprising Shiga toxin A subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2020·Granted Oct 5, 2021·10 cites·30 claims
- 0894US10421958B2Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicityMOLECULAR TEMPLATES INC·Filed 2015·Granted Sep 24, 2019·11 cites·23 claims
- 0993US11406692B2Cell-targeting molecules comprising de-immunized, Shiga toxin a subunit effectors and CD8+ t-cell epitopesMOLECULAR TEMPLATES INC·Filed 2021·Granted Aug 9, 2022·4 cites·15 claims
- 1090US2024409589A1Mhc class i epitope delivering polypeptidesMOLECULAR TEMPLATES INC·Filed 2024·Application pending·0 cites
- 1187US2024360184A1De-immunized shiga toxin a subunit effector polypeptides for applications in mammalsMOLECULAR TEMPLATES INC·Filed 2024·Application pending·0 cites
- 1285US2024082404A1Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugationMOLECULAR TEMPLATES INC·Filed 2023·Application pending·0 cites
- 1382US12037367B2MHC class I epitope delivering polypeptidesMOLECULAR TEMPLATES INC·Filed 2022·Granted Jul 16, 2024·0 cites·11 claims
- 1482US11918649B2PD-L1-binding molecules comprising Shiga toxin a subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2020·Granted Mar 5, 2024·1 cites·43 claims
- 1576US2023331785A1Her2-targeting molecules comprising de-immunized, shiga toxin a subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2023·Application pending·0 cites
- 1675US12065469B2De-immunized Shiga toxin a subunit effector polypeptides for applications in mammalsMOLECULAR TEMPLATES INC·Filed 2021·Granted Aug 20, 2024·0 cites·14 claims
- 1774US10131683B2TH-302 solid forms and methods related theretoMOLECULAR TEMPLATES INC·Filed 2015·Granted Nov 20, 2018·1 cites·16 claims
- 1872US2024207399A1Pd-l1-binding molecules comprising shiga toxin a subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2024·Application pending·0 cites
- 1972US2022354938A1Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopesMOLECULAR TEMPLATES INC·Filed 2022·Application pending·0 cites
- 2071US10450354B2CD20-binding immunotoxins for inducing cellular internalization and methods using sameMOLECULAR TEMPLATES INC·Filed 2014·Granted Oct 22, 2019·1 cites·40 claims
- 2170US11142584B2CD20-binding proteins comprising Shiga toxin A subunit effector regions for inducing cellular internalization and methods using sameMOLECULAR TEMPLATES INC·Filed 2015·Granted Oct 12, 2021·1 cites·18 claims
- 2270US11104707B2Multivalent CD20-binding molecules comprising Shiga toxin a subunit effector regions and enriched compositions thereofMOLECULAR TEMPLATES INC·Filed 2019·Granted Aug 31, 2021·0 cites·18 claims
- 2370US2022162271A1Her2-targeting molecules comprising de-immunized, shiga toxin a subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2021·Application pending·0 cites
- 2469US10392425B2Multivalent CD20-binding molecules comprising Shiga toxin A subunit effector regions and enriched compositions thereofMOLECULAR TEMPLATES INC·Filed 2016·Granted Aug 27, 2019·1 cites·24 claims
- 2568US7713915B1Cytotoxic heteromeric protein combinatorial librariesMOLECULAR TEMPLATES INC·Filed 1998·Granted May 11, 2010·21 cites·28 claims
- 2668US2022281926A1De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the sameMOLECULAR TEMPLATES INC·Filed 2022·Application pending·0 cites
- 2767US2019153044A1MHC Class I Epitope Delivering PolypeptidesMOLECULAR TEMPLATES INC·Filed 2018·Application pending·0 cites
- 2867US2022267384A1Proteins comprising binding regions, shiga toxin a subunit effector regions, and carboxy-terminal, endoplasmic reticulum localization signal motifsMOLECULAR TEMPLATES INC·Filed 2022·Application pending·0 cites
- 2965US10654876B2TH-302 solid forms and methods related theretoMOLECULAR TEMPLATES INC·Filed 2018·Granted May 19, 2020·0 cites·18 claims
- 3064US10668047B2Aziridine containing DNA alkylating agentsMOLECULAR TEMPLATES INC·Filed 2019·Granted Jun 2, 2020·0 cites·11 claims
- 3162US2021008208A1Shiga toxin a subunit effector polypeptides, shiga toxin effector scaffolds, and cell-targeting molecules for site-specific conjugationMOLECULAR TEMPLATES INC·Filed 2017·Application pending·0 cites
- 3261US12180284B2Clinical methods for use of a PD-L1-binding molecule comprising a Shiga toxin effectorMOLECULAR TEMPLATES INC·Filed 2021·Granted Dec 31, 2024·0 cites·41 claims
- 3361US2019060275A1Administration of hypoxia activated prodrugs and antiangiogenic agents for the treatment of cancerMOLECULAR TEMPLATES INC·Filed 2018·Application pending·0 cites
- 3460US2021017512A1Cell-targeting molecules comprising protease-cleavage resistant, shiga toxin a subunit effector polypeptides and carboxy-terminal moietiesMOLECULAR TEMPLATES INC·Filed 2020·Application pending·0 cites
- 3558US11248061B2Multivalent CD20-binding molecule comprising Shiga toxin A subunit effector polypeptides and enriched compositions thereofMOLECULAR TEMPLATES INC·Filed 2016·Granted Feb 15, 2022·0 cites·23 claims
- 3658US2019382755A1Methods of screening, selecting, and identifying cytotoxic recombinant polypeptides based on an interim diminution of ribotoxicityMOLECULAR TEMPLATES INC·Filed 2019·Application pending·0 cites
- 3758US2023357406A1Ctla-4 binding molecules comprising shiga toxin a subunit scaffolds and uses thereofMOLECULAR TEMPLATES INC·Filed 2023·Application pending·0 cites
- 3857US2022401568A1Cell-targeting molecules comprising shiga toxin a subunit effectors and cd8+ t-cell epitopesMOLECULAR TEMPLATES INC·Filed 2021·Application pending·0 cites
- 3957US2022306700A1Pd-l1 binding proteins comprising shiga toxin a subunit scaffolds and cd8+ t cell antigensMOLECULAR TEMPLATES INC·Filed 2022·Application pending·0 cites
- 4057US2020002387A1Cd20-binding immunotoxins for inducing cellular internalization and methods using sameMOLECULAR TEMPLATES INC·Filed 2019·Application pending·0 cites
- 4156US10071109B2Predictive biomarker for hypoxia-activated prodrug therapyMOLECULAR TEMPLATES INC·Filed 2014·Granted Sep 11, 2018·0 cites·6 claims
- 4256US2020024312A1Cell-targeting molecules comprising de-immunized, shiga toxin a subunit effectors and cd8+ t-cell epitopesMOLECULAR TEMPLATES INC·Filed 2018·Application pending·0 cites
- 4356US2016347798A1Mhc class i epitope delivering polypeptides and cell-targeted molecules for direct cell killing and immune stimulation via mhc class i presentation and methods regarding the sameMOLECULAR TEMPLATES INC·Filed 2015·Application pending·0 cites
- 4454US2018258144A1Cytotoxic proteins comprising cell-targeting binding regions and shiga toxin a subunit regions for selective killing of specific cell typesMOLECULAR TEMPLATES INC·Filed 2018·Application pending·0 cites
- 4553US2016340394A1De-immunized shiga toxin a subunit effector polypeptides for applications in mammalsMOLECULAR TEMPLATES INC·Filed 2015·Application pending·0 cites
- 4653US2021324082A1Pd-l1 targeting molecules comprising shiga toxin a subunit scaffoldsMOLECULAR TEMPLATES INC·Filed 2021·Application pending·0 cites
- 4753US2018291359A1Cell-targeting molecules comprising amino-terminus proximal or amino-terminal, shiga toxin a subunit effector regionsMOLECULAR TEMPLATES INC·Filed 2018·Application pending·0 cites
- 4851US2013196928A1Library from toxin mutants and methods of using sameMOLECULAR TEMPLATES INC·Filed 2013·Application pending·0 cites
- 4947US2018258143A1De-Immunized, Shiga Toxin A Subunit Scaffolds and Cell-Targeting Molecules Comprising the SameMOLECULAR TEMPLATES INC·Filed 2016·Application pending·0 cites
- 5047US2016177284A1Cell-targeted molecules comprising amino-terminus proximal or amino-terminal shiga toxin a subunit effector regionsMOLECULAR TEMPLATES INC·Filed 2015·Application pending·0 cites
Showing the top 50 of 57 patent records by PatentIndex Score.
Counts cover granted patents and pending applications in the PatentIndex corpus. How scoring works →