Assignee
NAPRO BIOTHERAPEUTICS INC
US·33 granted patents·887 citations·filing 1992–2001
Top patents by PatentIndex Score
33 records- 0196US5733888AInjectable compositionNAPRO BIOTHERAPEUTICS INC·Filed 1996·Granted Mar 31, 1998·164 cites·44 claims
- 0295US5202448AProcesses of converting taxanes into baccatin IIINAPRO BIOTHERAPEUTICS INC·Filed 1992·Granted Apr 13, 1993·134 cites·21 claims
- 0393US5688977AMethod for docetaxel synthesisNAPRO BIOTHERAPEUTICS INC·Filed 1996·Granted Nov 18, 1997·73 cites·24 claims
- 0491US5972992AInjectable compositionNAPRO BIOTHERAPEUTICS INC·Filed 1998·Granted Oct 26, 1999·72 cites·15 claims
- 0591US5281727AMethod of using ion exchange media to increase taxane yieldsNAPRO BIOTHERAPEUTICS INC·Filed 1992·Granted Jan 25, 1994·64 cites·17 claims
- 0688US6281368B1Simple and efficient hydrazinolysis of C-10 and C-13 ester functionalities of taxanes to obtain 10-DAB IIINAPRO BIOTHERAPEUTICS INC·Filed 2000·Granted Aug 28, 2001·25 cites·46 claims
- 0787US6306894B1Injectable compositionNAPRO BIOTHERAPEUTICS INC·Filed 2000·Granted Oct 23, 2001·15 cites·38 claims
- 0887US5977164AStabilized pharmaceutical compositionNAPRO BIOTHERAPEUTICS INC·Filed 1997·Granted Nov 2, 1999·55 cites·61 claims
- 0985US6307088B1Synthesis of taxol, taxol analogs and their intermediates with variable A-ring side chain structures and compositions thereofNAPRO BIOTHERAPEUTICS INC·Filed 2000·Granted Oct 23, 2001·10 cites·19 claims
- 1083US6495705B2Efficient process for the production of 10-DAB III by selective hydrazinolysis of various taxanesNAPRO BIOTHERAPEUTICS INC·Filed 2001·Granted Dec 17, 2002·14 cites·45 claims
- 1182US6358996B1Stable isotope labeling of paclitaxelNAPRO BIOTHERAPEUTICS INC·Filed 2000·Granted Mar 19, 2002·24 cites·35 claims
- 1278US5675025APaclitaxel synthesis from precursor compounds and methods of producing the sameNAPRO BIOTHERAPEUTICS INC·Filed 1995·Granted Oct 7, 1997·23 cites·8 claims
- 1377US6770670B2Injectable compositionNAPRO BIOTHERAPEUTICS INC·Filed 2001·Granted Aug 3, 2004·4 cites·265 claims
- 1475US6140359AInjectable compositionNAPRO BIOTHERAPEUTICS INC·Filed 1999·Granted Oct 31, 2000·26 cites·46 claims
- 1575US5256801AProcesses of converting taxanes into 10-deacetylbaccatin IIINAPRO BIOTHERAPEUTICS INC·Filed 1992·Granted Oct 26, 1993·16 cites·11 claims
- 1672US5750736AMethod for acylating 10-deacetylbaccatin III selectively at the c-10 positionNAPRO BIOTHERAPEUTICS INC·Filed 1996·Granted May 12, 1998·16 cites·24 claims
- 1770US6107497AIntermediate for use in docetaxel synthesis and production method thereforNAPRO BIOTHERAPEUTICS INC·Filed 1996·Granted Aug 22, 2000·14 cites·12 claims
- 1869US6048990AMethod for selective acylation of C-2'-O-protected-10-hydroxy-taxol at the C-10 positionNAPRO BIOTHERAPEUTICS INC·Filed 1998·Granted Apr 11, 2000·14 cites·23 claims
- 1968US6066749AMethod for conversion of C-2'-O-protected-10-hydroxy taxol to c-2'-O-protected taxol:useful intermediates in paclitaxel synthesisNAPRO BIOTHERAPEUTICS INC·Filed 1998·Granted May 23, 2000·13 cites·20 claims
- 2065US5696153ATherapeutic regimen for treating patientsNAPRO BIOTHERAPEUTICS INC·Filed 1996·Granted Dec 9, 1997·28 cites·12 claims
- 2164US5914411AAlternate method for acylating 10-deacetylbaccatin III selectively at the C-10 positionNAPRO BIOTHERAPEUTICS INC·Filed 1998·Granted Jun 22, 1999·10 cites·29 claims
- 2264US5684175AC-2' hydroxyl-benzyl protected, N-carbamate protected (2R, 3S)- 3-phenylisoserine and production process thereforNAPRO BIOTHERAPEUTICS INC·Filed 1995·Granted Nov 4, 1997·17 cites·5 claims
- 2363US6479679B1Two-step conversion of protected taxane ester to paclitaxelNAPRO BIOTHERAPEUTICS INC·Filed 2001·Granted Nov 12, 2002·2 cites·41 claims
- 2461US5948919APaclitaxel synthesis from precursor compounds and methods of producing the sameNAPRO BIOTHERAPEUTICS INC·Filed 1995·Granted Sep 7, 1999·16 cites·10 claims
- 2560US6136999AC-2 hydroxyl protected-n-acyl (2R,3S)-3-phenylisoserine substituted phenyl activated esters and method for production thereofNAPRO BIOTHERAPEUTICS INC·Filed 1999·Granted Oct 24, 2000·7 cites·22 claims
- 2659US6452025B1Three-step conversion of protected taxane ester to paclitaxelNAPRO BIOTHERAPEUTICS INC·Filed 2001·Granted Sep 17, 2002·1 cites·34 claims
- 2759US6133462AC-7 CBZ baccatin III and production method thereforNAPRO BIOTHERAPEUTICS INC·Filed 1997·Granted Oct 17, 2000·6 cites·14 claims
- 2850US6509484B2Synthesis of taxol, taxol analogs and their intermediates with variable a-ring side chain structures and compositions thereofNAPRO BIOTHERAPEUTICS INC·Filed 2001·Granted Jan 21, 2003·0 cites·2 claims
- 2945US6448417B1Methods and useful intermediates for paclitaxel synthesis from C-7, C-10 di-cbz 10-deacetylbaccatin IIINAPRO BIOTHERAPEUTICS INC·Filed 1999·Granted Sep 10, 2002·3 cites·30 claims
- 3044US6143902AC-2 hydroxyl protected-N-acyl (2R,3S)-3-phenylisoserine N-imido activated esters and method for production thereofNAPRO BIOTHERAPEUTICS INC·Filed 1999·Granted Nov 7, 2000·6 cites·34 claims
- 3142US5549830AReverse osmosis and ultrafiltration methods for solutions to isolate desired solutes including taxaneNAPRO BIOTHERAPEUTICS INC·Filed 1994·Granted Aug 27, 1996·11 cites·24 claims
- 3234US6653501B2Chiral resolution method for producing compounds useful in the synthesis of taxanesNAPRO BIOTHERAPEUTICS INC·Filed 2001·Granted Nov 25, 2003·0 cites·39 claims
- 3333US5688517AMethod for assessing sensitivity of tumor cells to cephalomannine and 10-deacetyltaxolNAPRO BIOTHERAPEUTICS INC·Filed 1993·Granted Nov 18, 1997·4 cites·15 claims
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