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NOBEX CORP

US41 patents

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US6858580B2Feb 22, 2005

Mixtures of drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same

NOBEX CORP114 citations97
US6703381B1Mar 9, 2004

Methods for delivery therapeutic compounds across the blood-brain barrier

NOBEX CORP97 citations97
US6835802B2Dec 28, 2004

Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties

NOBEX CORP53 citations96
US6815530B2Nov 9, 2004

Substantiallymonodispersed mixtures of polymers having polyethylene glycol moieties

NOBEX CORP49 citations96
US6930090B2Aug 16, 2005

Methods of activating a receptor using amphiphilic drug-oligomer conjugates

NOBEX CORP33 citations95
US6903082B2Jun 7, 2005

Methods of treating inflammatory conditions of the gastrointestinal tract using 4-APAA and compositions thereof

NOBEX CORP41 citations95
US6583128B2Jun 24, 2003

Immunoregulatory compounds and derivatives and methods of treating diseases therewith

NOBEX CORP50 citations95
US7030084B2Apr 18, 2006

Drug-oligomer conjugates with polyethylene glycol components

NOBEX CORP79 citations94
US6713454B1Mar 30, 2004

Prodrugs of etoposide and etoposide analogs

NOBEX CORP70 citations94
US6309633B1Oct 30, 2001

Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same

NOBEX CORP308 citations94
US7084114B2Aug 1, 2006

Mixtures of insulin drug-oligomer comprising polyalkylene glycol

NOBEX CORP22 citations92
US6913903B2Jul 5, 2005

Methods of synthesizing insulin polypeptide-oligomer conjugates, and proinsulin polypeptide-oligomer conjugates and methods of synthesizing same

NOBEX CORP14 citations92
US6828297B2Dec 7, 2004

Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same

NOBEX CORP33 citations92
US6713452B2Mar 30, 2004

Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same

NOBEX CORP26 citations92
US6541508B2Apr 1, 2003

Taxane prodrugs

NOBEX CORP36 citations92
US7119074B2Oct 10, 2006

Treatment of cancers, tumors and malignancies using amphiphilic prodrugs

NOBEX CORP16 citations91
US6380405B1Apr 30, 2002

Taxane prodrugs

NOBEX CORP49 citations91
US7060675B2Jun 13, 2006

Methods of treating diabetes mellitus

NOBEX CORP38 citations90
US7030082B2Apr 18, 2006

Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith

NOBEX CORP38 citations90
US6867183B2Mar 15, 2005

Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith

NOBEX CORP47 citations90
US6770625B2Aug 3, 2004

Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith

NOBEX CORP49 citations90
US6436990B1Aug 20, 2002

6-methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP17 citations90
US6479692B1Nov 12, 2002

Methods of synthesizing acylanilides including bicalutamide and derivatives thereof

NOBEX CORP27 citations89
US6943148B1Sep 13, 2005

Methods for delivering therapeutics across blood-barrier and for altering receptor binding affinity

NOBEX CORP15 citations88
US6458776B1Oct 1, 2002

5-ASA derivatives having anti-inflammatory and antibiotic activity and methods of treating diseases therewith

NOBEX CORP41 citations88
US6552078B2Apr 22, 2003

6-methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP14 citations83
US6638906B1Oct 28, 2003

Amphiphilic polymers and polypeptide conjugates comprising same

NOBEX CORP15 citations82
US6525098B1Feb 25, 2003

6-methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP14 citations82
US7119162B2Oct 10, 2006

Substantially monodispersed mixtures of polymers having polyethylene glycol moieties

NOBEX CORP7 citations73
US7084121B2Aug 1, 2006

Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same

NOBEX CORP5 citations73
US6828305B2Dec 7, 2004

Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same

NOBEX CORP9 citations73
US6593492B1Jul 15, 2003

Resolution of intermediates in the synthesis of substantially pure bicalutamide

NOBEX CORP9 citations73
US6583306B1Jun 24, 2003

Methods of asymmetrically synthesizing enantiomers of Casodex, its derivatives and intermediates thereof

NOBEX CORP10 citations73
US7151095B2Dec 19, 2006

Immunoregulatory compounds and derivatives and methods of treating diseases therewith

NOBEX CORP5 citations72
US7022869B2Apr 4, 2006

Methods of asymmetrically synthesizing enantiomers of casodex, its derivatives and intermediates thereof

NOBEX CORP4 citations62
US6713510B2Mar 30, 2004

6-Methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP3 citations60
US6610739B2Aug 26, 2003

6-methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP1 citations60
US6812362B2Nov 2, 2004

Methods of synthesizing acylanilides including bicalutamide and derivatives thereof

NOBEX CORP4 citations59
US6730701B2May 4, 2004

6-methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP0 citations51
US6956051B1Oct 18, 2005

Enkephalin conjugates

NOBEX CORP0 citations50
US6653348B2Nov 25, 2003

6-methoxy-2-naphthylacetic acid prodrugs

NOBEX CORP0 citations50