Assignee
OPKO HEALTH INC
US·16 granted patents·10 pending applications·98 citations·filing 2005–2019
Top patents by PatentIndex Score
26 records- 0192US7902366B2NK1 antagonistsOPKO HEALTH INC·Filed 2006·Granted Mar 8, 2011·19 cites·19 claims
- 0292US7709641B2NK1 antagonistsOPKO HEALTH INC·Filed 2005·Granted May 4, 2010·20 cites·30 claims
- 0391US7981905B2Pharmaceutical formulations: salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-Ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the sameOPKO HEALTH INC·Filed 2009·Granted Jul 19, 2011·24 cites·36 claims
- 0489US8026364B2NK1 antagonistsOPKO HEALTH INC·Filed 2010·Granted Sep 27, 2011·11 cites·39 claims
- 0588US8796299B2NK1 antagonistsOPKO HEALTH INC·Filed 2012·Granted Aug 5, 2014·9 cites·15 claims
- 0684US8361500B2Tablet formulations containing 8-[{1-(3,5-Bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one salts and tablets made therefromOPKO HEALTH INC·Filed 2008·Granted Jan 29, 2013·8 cites·9 claims
- 0778US9469629B2NK1 antagonistsOPKO HEALTH INC·Filed 2014·Granted Oct 18, 2016·2 cites·12 claims
- 0878US9345692B2Pharmaceutical formulations: salts of 8-[1-3,5-bis-(trifluoromethyl)phenyl)-ethoxy-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and treatment methods using the sameOPKO HEALTH INC·Filed 2013·Granted May 24, 2016·3 cites·5 claims
- 0971US9249144B2Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compoundsOPKO HEALTH INC·Filed 2013·Granted Feb 2, 2016·1 cites·7 claims
- 1069US9260428B2Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compoundsOPKO HEALTH INC·Filed 2013·Granted Feb 16, 2016·1 cites·9 claims
- 1164US9688693B2NK1 antagonistsOPKO HEALTH INC·Filed 2014·Granted Jun 27, 2017·0 cites·8 claims
- 1264US2018215729A1Nk 1 antagonistsOPKO HEALTH INC·Filed 2018·Application pending·0 cites
- 1362US9969711B2NK1 antagonistsOPKO HEALTH INC·Filed 2016·Granted May 15, 2018·0 cites·6 claims
- 1462US2019375751A1Hydrochloride salts of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one and preparation process thereforOPKO HEALTH INC·Filed 2019·Application pending·0 cites
- 1561US2017283434A1Nk1 antagonistsOPKO HEALTH INC·Filed 2017·Application pending·0 cites
- 1659US9006211B2Hypersulfated disaccharide formulationsOPKO HEALTH INC·Filed 2013·Granted Apr 14, 2015·0 cites·20 claims
- 1759US2013281477A1Hydrochloride salts of 8-[1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxymethyl]-8-phenyl-1,7-diazaspiro[4,5]decan-2-one and preparation process thereforOPKO HEALTH INC·Filed 2013·Application pending·0 cites
- 1856US10196394B2Hydrochloride salts of 8-[1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxymethyl]-8-phenyl-1,7-diazaspiro[4,5]decan-2-one and preparation process thereforOPKO HEALTH INC·Filed 2015·Granted Feb 5, 2019·0 cites·20 claims
- 1956US2015283121A1Tablet formulations containing 8-[-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one salts and tablets made therefromOPKO HEALTH INC·Filed 2014·Application pending·0 cites
- 2054US10000493B2Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compoundsOPKO HEALTH INC·Filed 2016·Granted Jun 19, 2018·0 cites·1 claims
- 2153US9822116B2Process and intermediates for the synthesis of 8-[{1-(3,5-bis-(trifluoromethyl)phenyl)-ethoxy}-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one compoundsOPKO HEALTH INC·Filed 2016·Granted Nov 21, 2017·0 cites·20 claims
- 2252US2013122088A1Tablet formulations containing 8-[-methyl]-8-phenyl-1,7-diaza-spiro[4.5]decan-2-one salts and tablets made therefromOPKO HEALTH INC·Filed 2013·Application pending·0 cites
- 2349US2016250242A1Hypersulfated disaccharide formulationsOPKO HEALTH INC·Filed 2016·Application pending·0 cites
- 2441US2015283157A1Hypersulfated disaccharides to treat elastase related disordersOPKO HEALTH INC·Filed 2015·Application pending·0 cites
- 2540US2016024092A1Intravenous formulations of neurokinin-1 antagonistsOPKO HEALTH INC·Filed 2015·Application pending·0 cites
- 2637US2011245197A1Hypersulfated glucopyranosidesOPKO HEALTH INC·Filed 2011·Application pending·0 cites
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