Assignee
SEATTLE CHILDRENS HOSPITAL
US·64 granted patents·1 pending application·187 citations·filing 2010–2024
Top patents by PatentIndex Score
65 records- 0198US11123369B2Bispecific CAR T-cells for solid tumor targetingSEATTLE CHILDRENS HOSPITAL·Filed 2020·Granted Sep 21, 2021·8 cites·16 claims
- 0297US11639387B2Bispecific chimeric antigen receptors, encoding polynucleotides thereof and methods of use thereof to treat diseaseSEATTLE CHILDRENS HOSPITAL·Filed 2020·Granted May 2, 2023·8 cites·17 claims
- 0397US10865242B2Method and compositions for cellular immunotherapySEATTLE CHILDRENS HOSPITAL·Filed 2015·Granted Dec 15, 2020·11 cites·17 claims
- 0497US10829556B2Polynucleotides encoding bispecific chimeric antigen receptorsSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Nov 10, 2020·14 cites·22 claims
- 0597US10266592B2Drug regulated transgene expressionSEATTLE CHILDRENS HOSPITAL·Filed 2015·Granted Apr 23, 2019·19 cites·25 claims
- 0697US10189903B2Bispecific chimeric antigen receptors and methods of use thereof to treat cancerSEATTLE CHILDRENS HOSPITAL·Filed 2016·Granted Jan 29, 2019·26 cites·87 claims
- 0796US11458167B2Bispecific CAR T-cells for solid tumor targetingSEATTLE CHILDRENS HOSPITAL·Filed 2016·Granted Oct 4, 2022·12 cites·14 claims
- 0896US11155616B2Drug regulated transgene expressionSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Oct 26, 2021·6 cites·19 claims
- 0995US12091459B2Bispecific chimeric antigen receptors, encoding polynucleotides and use of receptors thereof to treat cancerSEATTLE CHILDRENS HOSPITAL·Filed 2023·Granted Sep 17, 2024·2 cites·30 claims
- 1095US11311576B2Methods of use for CAR T cellsSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Apr 26, 2022·10 cites·23 claims
- 1195US10611837B2Transgene genetic tags and methods of useSEATTLE CHILDRENS HOSPITAL·Filed 2015·Granted Apr 7, 2020·9 cites·13 claims
- 1293US9943612B2Long poly(A) plasmids and methods for introduction of long poly(A) sequences into the plasmidSEATTLE CHILDRENS HOSPITAL·Filed 2015·Granted Apr 17, 2018·12 cites·11 claims
- 1392US11414486B2Transgene genetic tags and methods of useSEATTLE CHILDRENS HOSPITAL·Filed 2020·Granted Aug 16, 2022·2 cites·20 claims
- 1491US12466885B2Bispecific chimeric antigen receptors and encoding polynucleotides, vectors and cells thereofSEATTLE CHILDRENS HOSPITAL·Filed 2024·Granted Nov 11, 2025·0 cites·30 claims
- 1589US12378546B2Coupling endonucleases with end-processing enzymes drives high efficiency gene disruptionSEATTLE CHILDRENS HOSPITAL·Filed 2023·Granted Aug 5, 2025·0 cites·17 claims
- 1688US10525082B2Genetic engineering of macrophages for immunotherapySEATTLE CHILDRENS HOSPITAL·Filed 2016·Granted Jan 7, 2020·14 cites·11 claims
- 1786US11649288B2Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agentsSEATTLE CHILDRENS HOSPITAL·Filed 2018·Granted May 16, 2023·2 cites·20 claims
- 1885US11753460B2Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivoSEATTLE CHILDRENS HOSPITAL·Filed 2017·Granted Sep 12, 2023·2 cites·26 claims
- 1984US12448445B2Transgene genetic tags and methods of useSEATTLE CHILDRENS HOSPITAL·Filed 2022·Granted Oct 21, 2025·0 cites·17 claims
- 2084US12358970B2Methods of exogenous drug activation of chemical-induced signaling complexes expressed in engineered cells in vitro and in vivoSEATTLE CHILDRENS HOSPITAL·Filed 2023·Granted Jul 15, 2025·0 cites·20 claims
- 2184US2024210393A1Detection and treatment of autoimmune disordersSEATTLE CHILDRENS HOSPITAL·Filed 2023·Application pending·0 cites
- 2283US12503507B2Defined composition gene modified T-cell productsSEATTLE CHILDRENS HOSPITAL·Filed 2022·Granted Dec 23, 2025·0 cites·20 claims
- 2383US11408005B2Chimeric transcription factor variants with augmented sensitivity to drug ligand induction of transgene expression in mammalian cellsSEATTLE CHILDRENS HOSPITAL·Filed 2017·Granted Aug 9, 2022·3 cites·20 claims
- 2483US10919950B2Tumor-specific IFNA secretion by car T-cells to reprogram the solid tumor microenvironmentSEATTLE CHILDRENS HOSPITAL·Filed 2017·Granted Feb 16, 2021·2 cites·19 claims
- 2582US12433960B2Vivo gene therapy using intraosseous delivery of a lentiviralgene constructSEATTLE CHILDRENS HOSPITAL·Filed 2024·Granted Oct 7, 2025·0 cites·13 claims
- 2682US12202897B2Drug regulated transgene expressionSEATTLE CHILDRENS HOSPITAL·Filed 2021·Granted Jan 21, 2025·0 cites·23 claims
- 2782US12098208B2Early intervention methods to prevent or ameliorate toxicitySEATTLE CHILDRENS HOSPITAL·Filed 2023·Granted Sep 24, 2024·0 cites·20 claims
- 2882US11518814B2Early intervention methods to prevent or ameliorate toxicitySEATTLE CHILDRENS HOSPITAL·Filed 2017·Granted Dec 6, 2022·2 cites·20 claims
- 2982US10563226B2Enhancing endonuclease based gene editing in primary cellsSEATTLE CHILDRENS HOSPITAL·Filed 2016·Granted Feb 18, 2020·2 cites·14 claims
- 3081US11760804B2Early intervention methods to prevent or ameliorate toxicitySEATTLE CHILDRENS HOSPITAL·Filed 2022·Granted Sep 19, 2023·0 cites·15 claims
- 3181US8381723B2Broad-band, low frequency, high-amplitude, long time duration, oscillating airway pressure breathing apparatus and method utilizing bubblesSEATTLE CHILDRENS HOSPITAL·Filed 2010·Granted Feb 26, 2013·16 cites·39 claims
- 3280US12385070B2Homology directed repair compositions for the treatment of hemoglobinopathiesSEATTLE CHILDRENS HOSPITAL·Filed 2023·Granted Aug 12, 2025·0 cites·27 claims
- 3379US11826384B2Genetic engineering of macrophages for immunotherapySEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Nov 28, 2023·1 cites·20 claims
- 3478US11959073B2Coupling endonucleases with end-processing enzymes drives high efficiency gene disruptionSEATTLE CHILDRENS HOSPITAL·Filed 2021·Granted Apr 16, 2024·0 cites·20 claims
- 3578US11873479B2Coupling endonucleases with end-processing enzymes drives high efficiency gene disruptionSEATTLE CHILDRENS HOSPITAL·Filed 2021·Granted Jan 16, 2024·0 cites·16 claims
- 3677US11713459B2Expression of FOXP3 in edited CD34+ cellsSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Aug 1, 2023·2 cites·10 claims
- 3775US11987804B2Rapamycin resistant cellsSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted May 21, 2024·1 cites·29 claims
- 3873US12595492B2Rapamycin resistant cellsSEATTLE CHILDRENS HOSPITAL·Filed 2024·Granted Apr 7, 2026·0 cites·32 claims
- 3973US12258397B2Production of engineered T-cells by sleeping beauty transposon coupled with methotrexate selectionSEATTLE CHILDRENS HOSPITAL·Filed 2020·Granted Mar 25, 2025·0 cites·17 claims
- 4073US11253569B2Methods of treating Kawasaki DiseaseSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Feb 22, 2022·1 cites·59 claims
- 4171US11860161B2Detection and treatment of autoimmune disordersSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Jan 2, 2024·0 cites·10 claims
- 4270US10947529B2Coupling endonucleases with end-processing enzymes drives high efficiency gene disruptionSEATTLE CHILDRENS HOSPITAL·Filed 2016·Granted Mar 16, 2021·0 cites·36 claims
- 4369US11008565B2Coupling endonucleases with end-processing enzymes drives high efficiency gene disruptionSEATTLE CHILDRENS HOSPITAL·Filed 2016·Granted May 18, 2021·0 cites·68 claims
- 4467US12173071B2Methods and compositions comprising B7H3 chimeric antigen receptorsSEATTLE CHILDRENS HOSPITAL·Filed 2019·Granted Dec 24, 2024·0 cites·24 claims
- 4567US11851649B2Generating mammalian T cell activation inducible synthetic promoters (SYN+PRO) to improve T cell therapySEATTLE CHILDRENS HOSPITAL·Filed 2018·Granted Dec 26, 2023·0 cites·20 claims
- 4667US10995332B2Coupling endonucleases with end-processing enzymes drives high efficiency gene disruptionSEATTLE CHILDRENS HOSPITAL·Filed 2015·Granted May 4, 2021·0 cites·61 claims
- 4764US12070488B2Methods of treating Kawasaki diseaseSEATTLE CHILDRENS HOSPITAL·Filed 2022·Granted Aug 27, 2024·0 cites·20 claims
- 4864US11400169B2Long poly(A) plasmids and methods for introduction of long poly(A) sequences into the plasmidSEATTLE CHILDRENS HOSPITAL·Filed 2018·Granted Aug 2, 2022·0 cites·20 claims
- 4962US12110499B2Homology directed repair compositions for the treatment of hemoglobinopathiesSEATTLE CHILDRENS HOSPITAL·Filed 2018·Granted Oct 8, 2024·0 cites·18 claims
- 5059US11940448B2Proteomic screening for lysosomal storage diseasesSEATTLE CHILDRENS HOSPITAL·Filed 2021·Granted Mar 26, 2024·0 cites·21 claims
Showing the top 50 of 65 patent records by PatentIndex Score.
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