Assignee
SIGMA TAU IND FARMACEUTI
IT·309 granted patents·78 pending applications·2,993 citations·filing 1974–2016
Top patents by PatentIndex Score
387 records- 0198US6372940B1Process for the preparation of non-hygroscopic salts of L(−)-carnitineSIGMA TAU IND FARMACEUTI·Filed 2000·Granted Apr 16, 2002·78 cites·6 claims
- 0298US3968872ADevice, provided with a puncher and a dripper, for the hermetic sealing of containersSIGMA TAU IND FARMACEUTI·Filed 1974·Granted Jul 13, 1976·160 cites·2 claims
- 0395US6369073B1Compounds having reversible inhibiting activity of carnitine palmitoyl-transferaseSIGMA TAU IND FARMACEUTI·Filed 2000·Granted Apr 9, 2002·95 cites·21 claims
- 0494US6696493B2Treating chronic uremic patients undergoing periodic dialysisSIGMA TAU IND FARMACEUTI·Filed 2002·Granted Feb 24, 2004·32 cites·7 claims
- 0593US6063820AMedical food for diabeticsSIGMA TAU IND FARMACEUTI·Filed 1998·Granted May 16, 2000·120 cites·15 claims
- 0692US6429230B1Treating chronic uremic patients undergoing periodical dialysisSIGMA TAU IND FARMACEUTI·Filed 2001·Granted Aug 6, 2002·33 cites·16 claims
- 0792US6242457B1Camptothecin derivatives having antitumor activitySIGMA TAU IND FARMACEUTI·Filed 2000·Granted Jun 5, 2001·50 cites·17 claims
- 0891US7790700B2Derivatives of partially desulphated glycosaminoglycans endowed with antiangiogenic activity and devoid of anticoagulating effectSIGMA TAU IND FARMACEUTI·Filed 2005·Granted Sep 7, 2010·15 cites·25 claims
- 0991US4602039ASalts of-carnitine and alkanoyl L-carnitines and process for preparing sameSIGMA TAU IND FARMACEUTI·Filed 1984·Granted Jul 22, 1986·82 cites·16 claims
- 1089US4599232APharmaceutical composition with metabolic and energetic activity for the use in cardiac and vascular therapySIGMA TAU IND FARMACEUTI·Filed 1984·Granted Jul 8, 1986·102 cites·4 claims
- 1188US7098233B25-halo-tryptamine derivatives used as ligands on the 5-HT6 and/or 5-HT7 serotonin receptorsSIGMA TAU IND FARMACEUTI·Filed 2002·Granted Aug 29, 2006·55 cites·19 claims
- 1288US6335369B1Treating chronic uremic patients undergoing periodical dialysisSIGMA TAU IND FARMACEUTI·Filed 2001·Granted Jan 1, 2002·16 cites·14 claims
- 1387US6914076B2Treating chronic uremic patients undergoing periodical dialysisSIGMA TAU IND FARMACEUTI·Filed 2003·Granted Jul 5, 2005·19 cites·13 claims
- 1486US6610699B2Use of L-carnitine and its alkanoyl derivatives in the preparation of medicaments with anticancer activitySIGMA TAU IND FARMACEUTI·Filed 2001·Granted Aug 26, 2003·17 cites·8 claims
- 1585US7449495B2Retinoid derivatives with antiangiogenic, antitumoral and proapoptotic activitiesSIGMA TAU IND FARMACEUTI·Filed 2007·Granted Nov 11, 2008·7 cites·10 claims
- 1685US6444701B1Compounds having reversible inhibiting activity of carnitine palmitoyl-transferaseSIGMA TAU IND FARMACEUTI·Filed 2001·Granted Sep 3, 2002·19 cites·20 claims
- 1785US6166077AUse of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1SIGMA TAU IND FARMACEUTI·Filed 2000·Granted Dec 26, 2000·18 cites·18 claims
- 1884US6380252B1Use of L-acetylcarnitine, L-isovalerylcarnitine, L-propionylcarnitine for increasing the levels of IGF-1SIGMA TAU IND FARMACEUTI·Filed 2000·Granted Apr 30, 2002·15 cites·20 claims
- 1984US5721227A17-aryl and 17-heterocyclyl-14β-5α-androstane, androstene and androstadiene derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing sameSIGMA TAU IND FARMACEUTI·Filed 1995·Granted Feb 24, 1998·46 cites·4 claims
- 2084US4371618AProcess for enzymatically producing L-carnitineSIGMA TAU IND FARMACEUTI·Filed 1981·Granted Feb 1, 1983·26 cites·9 claims
- 2182US7854939B2Gel useful for the delivery of cosmetic active ingredientsSIGMA TAU IND FARMACEUTI·Filed 2007·Granted Dec 21, 2010·3 cites·4 claims
- 2282US7683032B2Deglycosylated and desialidated long pentraxin PTX3SIGMA TAU IND FARMACEUTI·Filed 2005·Granted Mar 23, 2010·8 cites·25 claims
- 2382US7655698B2Use of L-carnitine or of alkanoyl L-carnitines for the preparation of a physiological supplement or medicament for opthalmic use in the form of eye dropsSIGMA TAU IND FARMACEUTI·Filed 2006·Granted Feb 2, 2010·7 cites·7 claims
- 2482US5753703APharmaceutical composition comprising L-carnitine or an alkanoyl L-carnitine in combination with a polyunsaturated fatty acid of the omega-3 series for the prevention and the treatment of lipid metabolism disordersSIGMA TAU IND FARMACEUTI·Filed 1996·Granted May 19, 1998·55 cites·13 claims
- 2581US5747536APharmaceutical composition comprising L-carnitine or derivative thereof and trihydroxy or tetrahydroxystilbeneSIGMA TAU IND FARMACEUTI·Filed 1996·Granted May 5, 1998·54 cites·20 claims
- 2681US5432199AUse of acetyl D-carnitine in the therapeutic treatment of glaucoma, and pharmaceutical compositions useful in such treatmentSIGMA TAU IND FARMACEUTI·Filed 1991·Granted Jul 11, 1995·35 cites·2 claims
- 2781US5145871AUse of acetyl d-carnitine in the therapeutic treatment of glaucoma, and pharmaceutical compositions useful in such treatmentSIGMA TAU IND FARMACEUTI·Filed 1989·Granted Sep 8, 1992·48 cites·6 claims
- 2881US5037851AUse of acetyl l-carnitine in the therapeutic treatment of cataract, and pharmaceutical compositions useful in such treatmentSIGMA TAU IND FARMACEUTI·Filed 1989·Granted Aug 6, 1991·26 cites·1 claims
- 2980US8003109B2Pharmaceutical compositions containing the long pentraxin PTX3SIGMA TAU IND FARMACEUTI·Filed 2007·Granted Aug 23, 2011·5 cites·1 claims
- 3080US7498340B2Esters in position 20 of camptothecinsSIGMA TAU IND FARMACEUTI·Filed 2007·Granted Mar 3, 2009·4 cites·6 claims
- 3180US4244467ADevice for the extemporaneous preparation of a solution under sterile conditionsSIGMA TAU IND FARMACEUTI·Filed 1979·Granted Jan 13, 1981·42 cites·5 claims
- 3279US4382092APharmaceutical composition comprising gamma-butyrobetaine for the treatment of syndromes induced by L-carnitine deficiencySIGMA TAU IND FARMACEUTI·Filed 1981·Granted May 3, 1983·16 cites·5 claims
- 3378US6780851B1Composition for the prevention and/or treatment of disorders due to abnormal lipid metabolism, comprising propionyl l-carnitine and chitosanSIGMA TAU IND FARMACEUTI·Filed 2000·Granted Aug 24, 2004·8 cites·9 claims
- 3478US6696492B1Use of L carnitine and its alkanoyl dervatives for the preparation of a medicament useful for the treatment of patients suffering from diabetic and/or dysmetabolic nephropathySIGMA TAU IND FARMACEUTI·Filed 2000·Granted Feb 24, 2004·16 cites·5 claims
- 3578US5498633AEsters of acyl carnitines with long-chain aliphatic alcohols and pharmaceutical compositions containing same having antibacterial activitySIGMA TAU IND FARMACEUTI·Filed 1995·Granted Mar 12, 1996·16 cites·11 claims
- 3678US4401827ANovel acyl-derivatives of carnitine and process for their preparationSIGMA TAU IND FARMACEUTI·Filed 1981·Granted Aug 30, 1983·20 cites·5 claims
- 3777US6797281B1Esters of I-carnitine or alkanoyl I-carnitinesSIGMA TAU IND FARMACEUTI·Filed 2000·Granted Sep 28, 2004·9 cites·26 claims
- 3877US6528684B1Synthesis of (R) and (S) -aminocarnitine and their derivatives starting from D- and L-aspartic acidSIGMA TAU IND FARMACEUTI·Filed 2000·Granted Mar 4, 2003·10 cites·6 claims
- 3977US6451972B1Peptido-mimetic compounds containing RGD sequence useful as integrin inhibitorsSIGMA TAU IND FARMACEUTI·Filed 2001·Granted Sep 17, 2002·4 cites·2 claims
- 4077US6348495B1Method for treating celiac diseaseSIGMA TAU IND FARMACEUTI·Filed 2000·Granted Feb 19, 2002·8 cites·20 claims
- 4177US4681755ADelivery device for zero-order release of an active principle into a dissolution fluid and process for its preparationSIGMA TAU IND FARMACEUTI·Filed 1985·Granted Jul 21, 1987·54 cites·16 claims
- 4276US7888368B2Treatment of drug-resistant tumorsSIGMA TAU IND FARMACEUTI·Filed 2006·Granted Feb 15, 2011·2 cites·2 claims
- 4376US7705012B2Camptothecins conjugated in position 7 to cyclic peptides as cytostatic agentsSIGMA TAU IND FARMACEUTI·Filed 2005·Granted Apr 27, 2010·4 cites·11 claims
- 4475US6337197B2Coenzymes useful for the synthesis of L-carnitineSIGMA TAU IND FARMACEUTI·Filed 2001·Granted Jan 8, 2002·7 cites·2 claims
- 4574US6589939B2Camptothecin derivatives having antitumor activitySIGMA TAU IND FARMACEUTI·Filed 2000·Granted Jul 8, 2003·6 cites·4 claims
- 4674US6379936B1Coenzymes useful for the synthesis of L-carnitineSIGMA TAU IND FARMACEUTI·Filed 2001·Granted Apr 30, 2002·8 cites·2 claims
- 4774US4882349APyrrolacetic amides having antiinflammatory activitySIGMA TAU IND FARMACEUTI·Filed 1985·Granted Nov 21, 1989·17 cites·11 claims
- 4873USRE41226ECompounds having reversible inhibiting activity of carnitine palmitoyl-transferaseSIGMA TAU IND FARMACEUTI·Filed 2006·Granted Apr 13, 2010·1 cites·20 claims
- 4973USRE40861ECompounds having reversible inhibiting activity of carnitine palmitoyl-transferaseSIGMA TAU IND FARMACEUTI·Filed 2006·Granted Jul 21, 2009·1 cites·21 claims
- 5073US7041648B2Compositions and methods for treating female fertilitySIGMA TAU IND FARMACEUTI·Filed 2004·Granted May 9, 2006·11 cites·2 claims
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