Assignee
SYNAFFIX BV
NL29 patents
Top patents by PatentIndex Score
US9504758B2Nov 29, 2016
Modified antibody, antibody-conjugate and process for the preparation thereof
SYNAFFIX BV65 citations97
US10266502B2Apr 23, 2019
Process for the cycloaddition of a halogenated 1,3-dipole compound with a (hetero)cycloalkyne
SYNAFFIX BV78 citations96
US10239807B2Mar 26, 2019
Fused cyclooctyne compounds and their use in metal-free click reactions
SYNAFFIX BV57 citations96
US9222940B2Dec 29, 2015
Fused cyclooctyne compounds and their use in metal-free click reactions
SYNAFFIX BV91 citations95
US9636421B2May 2, 2017
Sulfamide linker, conjugates thereof, and methods of preparation
SYNAFFIX BV14 citations91
US9988661B2Jun 5, 2018
Process for the modification of a glycoprotein using a glycosyltransferase that is or is derived from A β(1,4)-N-acetylgalactosaminyltransferase
SYNAFFIX BV5 citations83
US11338043B2May 24, 2022
Antibody-conjugates with improved therapeutic index for targeting HER2 tumours and method for improving therapeutic index of antibody-conjugates
SYNAFFIX BV8 citations82
US10072096B2Sep 11, 2018
Modified glycoprotein, protein-conjugate and process for the preparation thereof
SYNAFFIX BV9 citations82
US11168085B2Nov 9, 2021
Process for the cycloaddition of a hetero(aryl) 1,3-dipole compound with a (hetero)cycloalkyne
SYNAFFIX BV2 citations72
US9987373B2Jun 5, 2018
Modified glycoprotein, protein-conjugate and process for the preparation thereof
SYNAFFIX BV3 citations72
US11358921B2Jun 14, 2022
Fused cyclooctyne compounds and their use in metal-free click reactions
SYNAFFIX BV1 citations71
US10792369B2Oct 6, 2020
Sulfamide linker, conjugates thereof, and methods of preparation
SYNAFFIX BV3 citations71
US11547763B2Jan 10, 2023
Enediyne conjugates
SYNAFFIX BV3 citations65
US12194107B2Jan 14, 2025
Modified antibody, antibody-conjugate and process for the preparation thereof
SYNAFFIX BV0 citations62
US12084448B2Sep 10, 2024
Process for the cycloaddition of a (hetero)aryl 1,3-dipole compound with a (hetero)cycloalkyne
SYNAFFIX BV0 citations61
US12049656B2Jul 30, 2024
Process for the modification of a glycoprotein using a glycosyltransferase that is or is derived from a β(1,4)-n-acetylgalactosaminyltransferase
SYNAFFIX BV0 citations61
US11957763B2Apr 16, 2024
Sulfamide linkers for use in bioconjugates
SYNAFFIX BV0 citations61
US11951175B2Apr 9, 2024
Bioconjugates containing sulfamide linkers for use in treatment
SYNAFFIX BV1 citations61
US11850286B2Dec 26, 2023
Sulfamide linker, conjugates thereof, and methods of preparation
SYNAFFIX BV1 citations61
US11299759B2Apr 12, 2022
Process for the modification of a glycoprotein using a glycosyltransferase that is or is derived from a β(1,4)-n-acetylgalactosaminyltransferase
SYNAFFIX BV1 citations61
US11713453B2Aug 1, 2023
Enzymes for trimming of glycoproteins
SYNAFFIX BV0 citations60
US11590239B2Feb 28, 2023
Antibody-conjugates with improved therapeutic index for targeting CD30 tumours and method for improving therapeutic index of antibody-conjugates
SYNAFFIX BV0 citations57
US12440573B2Oct 14, 2025
Antibody-conjugates for targeting of tumours expressing PTK7
SYNAFFIX BV0 citations56
US12180145B2Dec 31, 2024
Fused cyclooctyne compounds and their use in metal-free click reactions
SYNAFFIX BV0 citations55
US10874746B2Dec 29, 2020
Sulfamide linkers for use in bioconjugates
SYNAFFIX BV0 citations50
US12397063B2Aug 26, 2025
Antibody-conjugates for targeting of tumours expressing Trop-2
SYNAFFIX BV0 citations49
US12281135B2Apr 22, 2025
Synthesis of 6-azido-6-deoxy-2-n-acetyl-hexosamine-nucleoside diphosphate
SYNAFFIX BV0 citations49
US10858641B2Dec 8, 2020
Enzymes for trimming of glycoproteins
SYNAFFIX BV0 citations46
US11046988B2Jun 29, 2021
Process for the modification of a glycoprotein using a β-(1,4)-N-acetylgalactosaminyl transferase or a mutant thereof
SYNAFFIX BV0 citations44