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UNITY BIOTECHNOLOGY INC

US26 patents

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US10195213B2Feb 5, 2019

Chemical entities that kill senescent cells for use in treating age-related disease

UNITY BIOTECHNOLOGY INC15 citations94
US10328073B2Jun 25, 2019

Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells

UNITY BIOTECHNOLOGY INC9 citations92
US10130628B2Nov 20, 2018

Treatment of joint pain

UNITY BIOTECHNOLOGY INC6 citations91
US10517866B2Dec 31, 2019

Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitor

UNITY BIOTECHNOLOGY INC5 citations83
US10478433B2Nov 19, 2019

Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss

UNITY BIOTECHNOLOGY INC4 citations83
US10981892B2Apr 20, 2021

Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC2 citations73
US10717722B2Jul 21, 2020

Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC2 citations73
US10519197B1Dec 31, 2019

Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC3 citations73
US10426788B2Oct 1, 2019

Chemical entities that kill senescent cells for use in treating age-related disease

UNITY BIOTECHNOLOGY INC2 citations73
US10279018B2May 7, 2019

Immunogenic compositions for inducing an immune response for elimination of senescent cells

UNITY BIOTECHNOLOGY INC3 citations71
US10550378B2Feb 4, 2020

Composition comprising a gene vector that selectively depletes P16 positive senescent cells

UNITY BIOTECHNOLOGY INC2 citations70
US10378002B2Aug 13, 2019

Replication conditional virus that specifically kills senescent cells

UNITY BIOTECHNOLOGY INC2 citations70
US11129838B2Sep 28, 2021

Methods of inhibiting pathological angiogenesis

UNITY BIOTECHNOLOGY INC2 citations68
US10588916B2Mar 17, 2020

Technology to inhibit vascular changes that lead to vision loss in the eye

UNITY BIOTECHNOLOGY INC2 citations68
US12221433B2Feb 11, 2025

Acyl sulfonamides that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC0 citations62
US11865123B2Jan 9, 2024

Methods of inhibiting pathological angiogenesis

UNITY BIOTECHNOLOGY INC0 citations57
US12195542B2Jan 14, 2025

Antibodies directed to Tie-2 and methods of use

UNITY BIOTECHNOLOGY INC1 citations52
US10689416B2Jun 23, 2020

Peptide-based proteasome inhibitors for treating conditions mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC0 citations52
US11111259B2Sep 7, 2021

Acylsulfonamide derivatives for treating senescence-associated diseases and disorders

UNITY BIOTECHNOLOGY INC0 citations50
US10329279B2Jun 25, 2019

Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use

UNITY BIOTECHNOLOGY INC0 citations50
US9988368B1Jun 5, 2018

Chiral synthesis method for producing cis-imidazoline compounds for pharmaceutical use

UNITY BIOTECHNOLOGY INC1 citations50
US11951115B2Apr 9, 2024

Methods of treating retinal vasculopathies

UNITY BIOTECHNOLOGY INC0 citations49
US10745429B2Aug 18, 2020

Phospholidines that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC0 citations41
US10703745B2Jul 7, 2020

Acyl phosphonamidates and acyl benzylamines that are Bcl family antagonists for use in clinical management of conditions caused or mediated by senescent cells and for treating cancer

UNITY BIOTECHNOLOGY INC0 citations41
US10745445B2Aug 18, 2020

Conjugates that are configured for targeted delivery of therapeutic compounds to senescent cells

UNITY BIOTECHNOLOGY INC0 citations38
US9969776B2May 15, 2018

Drug conjugates for delivering compounds to senescent cells

UNITY BIOTECHNOLOGY INC1 citations38