Assignee

YAMASA SHOYU KK

JP51 patents

Top patents by PatentIndex Score

US4956345ASep 11, 1990

2-alkynyladenosines as antihypertensive agents

YAMASA SHOYU KK100 citations96

US5459254AOct 17, 1995

Process for preparing synthetic intermediates of 2-alkynyladenosines and 2-alkynyladenosines

YAMASA SHOYU KK52 citations95

US5939543AAug 17, 1999

Stable solid 2-octynyl adenosine and process for producing the same

YAMASA SHOYU KK49 citations94

US5270304ADec 14, 1993

Therapeutic 2-alkynyl adenosine agent for ischemic diseases of the heart or brain

YAMASA SHOYU KK57 citations94

US5189027AFeb 23, 1993

2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases

YAMASA SHOYU KK101 citations93

US4614714ASep 30, 1986

Use of novel L-glutamic acid oxidase

YAMASA SHOYU KK31 citations91

US5506110AApr 9, 1996

Carrier for binding of anti-phospholipid antibodies, and immunoassay method using the same and a kit therefor

YAMASA SHOYU KK38 citations89

US4115538ASep 19, 1978

1-β-D-Arabinofuranosyl-(E)-5-(2-halogenovinyl)-uracil-5'-phosphate, preparation thereof and use thereof

YAMASA SHOYU KK25 citations82

US5047520ASep 10, 1991

2'-alkylidenepyrimidine nucleoside derivatives, process for production thereof, and uses thereof

YAMASA SHOYU KK15 citations81

US4478934AOct 23, 1984

Determination of adenosine by immunoassay involving acylation of the adenosine

YAMASA SHOYU KK20 citations80

US5258301ANov 2, 1993

Process for producing nucleosides

YAMASA SHOYU KK12 citations79

US4434788AMar 6, 1984

Enhancer of anti-tumor effect

YAMASA SHOYU KK21 citations78

US4386076AMay 31, 1983

(E)-5-(2-Halogenovinyl)-arabinofuranosyluracil, process for preparation thereof, and uses thereof

YAMASA SHOYU KK15 citations74

US5026835AJun 25, 1991

Pyrimidine 2'-methylidene nucleoside compounds

YAMASA SHOYU KK9 citations73

US4350761ASep 21, 1982

Method of and reagents for quantitative analysis of cyclic nucleotides

YAMASA SHOYU KK17 citations73

US5384251AJan 24, 1995

Process for producing nucleosides

YAMASA SHOYU KK4 citations71

US4623626ANov 18, 1986

L-glutamic acid oxidase and its production

YAMASA SHOYU KK9 citations71

US4594321AJun 10, 1986

Process for producing 3-deoxyguanosine

YAMASA SHOYU KK11 citations71

US4109079AAug 22, 1978

Stabilized s-adenosyl-l-methionine preparations

YAMASA SHOYU KK12 citations71

US5059590AOct 22, 1991

Imidazole derivatives, process for production thereof, and use thereof

YAMASA SHOYU KK9 citations70

US4943427AJul 24, 1990

Diagnostic agent for heart disease and use thereof

YAMASA SHOYU KK8 citations70

US4767843AAug 30, 1988

Monoclonal antibody to cardiac myosin heavy chain

YAMASA SHOYU KK8 citations70

US4812560AMar 14, 1989

Process for producing 1-β-D-arabinofuranosylcytosine-5'-stearylphosphate monosodium salt and monohydrate thereof

YAMASA SHOYU KK8 citations69

US4432348AFeb 21, 1984

Enhancer of anti-tumor effect

YAMASA SHOYU KK9 citations69

US4234691ANov 18, 1980

L-Lysine α-oxidase

YAMASA SHOYU KK13 citations69

US4594320AJun 10, 1986

Process for producing 3-deoxyguanosine

YAMASA SHOYU KK7 citations68

US4542021ASep 17, 1985

Antitumor compositions for non-injection administration

YAMASA SHOYU KK18 citations68

US4614719ASep 30, 1986

Process for producing ribavirin

YAMASA SHOYU KK11 citations64

US5334593AAug 2, 1994

Anxiolytic drugs

YAMASA SHOYU KK2 citations63

US5252576AOct 12, 1993

1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient

YAMASA SHOYU KK5 citations63

US4344937AAug 17, 1982

Antiviral agent comprising 1-β-D-arabinofuranosylthymine

YAMASA SHOYU KK3 citations63

US5304471AApr 19, 1994

Process for producing foreign protein in Escherichia coli

YAMASA SHOYU KK3 citations62

US5430139AJul 4, 1995

2'-alkylidenepyrimidine nucleoside derivatives, process for production thereof, and uses thereof

YAMASA SHOYU KK1 citations61

US5300636AApr 5, 1994

2'-alkylidenepyrimidine nucleoside compounds and a process for production of same

YAMASA SHOYU KK4 citations61

US5283327AFeb 1, 1994

Tri-O-acetyl-2-alkynyladenosines

YAMASA SHOYU KK2 citations61

US4495355AJan 22, 1985

Optically-active diamide derivatives

YAMASA SHOYU KK3 citations61

US4015066AMar 29, 1977

Crystalline monosodium N6,2'-O-dibutyryl-adenosine-3',5'-cyclic monophosphate and production thereof

YAMASA SHOYU KK2 citations61

US5747652AMay 5, 1998

Antibody to smooth muscle myosin heavy chains

YAMASA SHOYU KK2 citations60

US5126361AJun 30, 1992

Imidazole derivatives and use thereof

YAMASA SHOYU KK2 citations59

US3930955AJan 6, 1976

Process for producing pterin deaminases having antitumor activity

YAMASA SHOYU KK5 citations58

US4320225AMar 16, 1982

Periandrins extracted from plants of the genus Periandra

YAMASA SHOYU KK5 citations56

US5298397AMar 29, 1994

Method of assaying d-vanillylmandelic acid

YAMASA SHOYU KK3 citations51

US4767713AAug 30, 1988

Pure culture of Brevibacterium acetylicum AT-6-7, ATCC 39311

YAMASA SHOYU KK0 citations50

US4668778AMay 26, 1987

Nucleoside 5'-alkyl- or alkenylphosphate

YAMASA SHOYU KK1 citations50

US4054735AOct 18, 1977

Stabilized N2,2-O-dibutyrylguanosine-3,5-cyclic phosphate and salts thereof

YAMASA SHOYU KK0 citations50

US5506122AApr 9, 1996

Process for producing nucleosides

YAMASA SHOYU KK0 citations49

Showing the top 50 of 51 patents by PatentIndex Score.

YAMASA SHOYU KK

Top patents by PatentIndex Score

2-alkynyladenosines as antihypertensive agents

Process for preparing synthetic intermediates of 2-alkynyladenosines and 2-alkynyladenosines

Stable solid 2-octynyl adenosine and process for producing the same

Therapeutic 2-alkynyl adenosine agent for ischemic diseases of the heart or brain

2-substituted adenosine derivatives and pharmaceutical compositions for circulatory diseases

Use of novel L-glutamic acid oxidase

Carrier for binding of anti-phospholipid antibodies, and immunoassay method using the same and a kit therefor

Assay kit for cAMP and/or cGMP and method of using the same

Method for deoxygenation of alcohols

S-Adenosyl-L-methionine compositions and production thereof

Methods for determining anti-phospholipid and anti-cardiolipin antibodies

1-β-D-Arabinofuranosyl-(E)-5-(2-halogenovinyl)-uracil-5&#39;-phosphate, preparation thereof and use thereof

2&#39;-alkylidenepyrimidine nucleoside derivatives, process for production thereof, and uses thereof

Determination of adenosine by immunoassay involving acylation of the adenosine

Process for producing nucleosides

Enhancer of anti-tumor effect

(E)-5-(2-Halogenovinyl)-arabinofuranosyluracil, process for preparation thereof, and uses thereof

Pyrimidine 2&#39;-methylidene nucleoside compounds

Method of and reagents for quantitative analysis of cyclic nucleotides

Process for producing nucleosides

L-glutamic acid oxidase and its production

Process for producing 3-deoxyguanosine

Stabilized s-adenosyl-l-methionine preparations

Imidazole derivatives, process for production thereof, and use thereof

Diagnostic agent for heart disease and use thereof

Monoclonal antibody to cardiac myosin heavy chain

Process for producing 1-β-D-arabinofuranosylcytosine-5&#39;-stearylphosphate monosodium salt and monohydrate thereof

Enhancer of anti-tumor effect

L-Lysine α-oxidase

Process for producing 3-deoxyguanosine

Antitumor compositions for non-injection administration

Process for producing ribavirin

Anxiolytic drugs

1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient

Antiviral agent comprising 1-β-D-arabinofuranosylthymine

Process for producing foreign protein in Escherichia coli

2&#39;-alkylidenepyrimidine nucleoside derivatives, process for production thereof, and uses thereof

2&#39;-alkylidenepyrimidine nucleoside compounds and a process for production of same

Tri-O-acetyl-2-alkynyladenosines

Optically-active diamide derivatives

Crystalline monosodium N6,2&#39;-O-dibutyryl-adenosine-3&#39;,5&#39;-cyclic monophosphate and production thereof

Antibody to smooth muscle myosin heavy chains

Imidazole derivatives and use thereof

Process for producing pterin deaminases having antitumor activity

Periandrins extracted from plants of the genus Periandra

Method of assaying d-vanillylmandelic acid

Pure culture of Brevibacterium acetylicum AT-6-7, ATCC 39311

Nucleoside 5&#39;-alkyl- or alkenylphosphate

Stabilized N2,2-O-dibutyrylguanosine-3,5-cyclic phosphate and salts thereof

Process for producing nucleosides

1-β-D-Arabinofuranosyl-(E)-5-(2-halogenovinyl)-uracil-5'-phosphate, preparation thereof and use thereof

2'-alkylidenepyrimidine nucleoside derivatives, process for production thereof, and uses thereof

Pyrimidine 2'-methylidene nucleoside compounds

Process for producing 1-β-D-arabinofuranosylcytosine-5'-stearylphosphate monosodium salt and monohydrate thereof

2'-alkylidenepyrimidine nucleoside derivatives, process for production thereof, and uses thereof

2'-alkylidenepyrimidine nucleoside compounds and a process for production of same

Crystalline monosodium N6,2'-O-dibutyryl-adenosine-3',5'-cyclic monophosphate and production thereof

Nucleoside 5'-alkyl- or alkenylphosphate