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ZYMOGENETICS INC

US618 patents

Top patents by PatentIndex Score

US7939068B2May 10, 2011

Antagonizing signal transduction in dorsal root ganglion cells in a subject with IL-31 antagonists

ZYMOGENETICS INC55 citations99
US7638126B2Dec 29, 2009

Methods of treating pain and inflammation in neuronal tissue using antagonists of IL-31, IL31Ra and/or OSMRb

ZYMOGENETICS INC60 citations99
US7514077B2Apr 7, 2009

Methods of antagonizing signal transduction in dorsal root ganglion cells with IL-31 antagonists

ZYMOGENETICS INC65 citations99
US7425325B2Sep 16, 2008

Cytokine zcytor17 ligand polypeptides

ZYMOGENETICS INC59 citations99
US7252969B2Aug 7, 2007

Interferon-like protein Zcyto21

ZYMOGENETICS INC69 citations99
US7253261B2Aug 7, 2007

Interferon-like protein Zcyto21

ZYMOGENETICS INC67 citations99
US7241870B2Jul 10, 2007

Interferon-like protein Zcyto21

ZYMOGENETICS INC67 citations99
US7157559B2Jan 2, 2007

Homogeneous preparations of IL-28 and IL-29

ZYMOGENETICS INC108 citations99
US7064186B2Jun 20, 2006

Cytokine zcytor17 ligand

ZYMOGENETICS INC125 citations99
US7038032B2May 2, 2006

Cytokine protein family

ZYMOGENETICS INC101 citations99
US6927040B2Aug 9, 2005

Interferon-like protein Zcyto21

ZYMOGENETICS INC125 citations99
US6686178B2Feb 3, 2004

Cytokine zalpha11 ligand polynucleotides

ZYMOGENETICS INC113 citations99
US6605272B2Aug 12, 2003

Methods of using zalpha11 ligand

ZYMOGENETICS INC117 citations99
US6307024B1Oct 23, 2001

Cytokine zalpha11 Ligand

ZYMOGENETICS INC232 citations99
US4845075AJul 4, 1989

Biologically active B-chain homodimers

ZYMOGENETICS INC203 citations99
US7531636B2May 12, 2009

Antibodies to murine zcytor17 ligand

ZYMOGENETICS INC62 citations98
US7531637B2May 12, 2009

IL-31 monoclonal antibodies

ZYMOGENETICS INC87 citations98
US7507795B2Mar 24, 2009

Murine ZCYTOR17 ligand polypeptides

ZYMOGENETICS INC52 citations98
US7494804B2Feb 24, 2009

Polynucleotide encoding cytokine receptor zcytor17 multimer

ZYMOGENETICS INC66 citations98
US7351689B2Apr 1, 2008

Use of IL-28 and IL-29 to treat cancer and autoimmune disorders

ZYMOGENETICS INC68 citations98
US6498235B2Dec 24, 2002

Testis specific glycoprotein zpep10

ZYMOGENETICS INC214 citations98
US6323323B1Nov 27, 2001

Ligand-binding, dimerized polypeptide fusions

ZYMOGENETICS INC196 citations98
US6300099B1Oct 9, 2001

Methods for producing secreted ligand-binding fusion proteins

ZYMOGENETICS INC129 citations98
US6291212B1Sep 18, 2001

DNA constructs encoding ligand-binding fusion proteins

ZYMOGENETICS INC134 citations98
US6291646B1Sep 18, 2001

Dimerized polypeptide fusions

ZYMOGENETICS INC146 citations98
US6251901B1Jun 26, 2001

Compositions and methods for treating bone deficit conditions

ZYMOGENETICS INC84 citations98
US6153631ANov 28, 2000

Compositions and methods for treating bone deficit conditions

ZYMOGENETICS INC102 citations98
US6018026AJan 25, 2000

Biologically active dimerized and multimerized polypeptide fusions

ZYMOGENETICS INC148 citations98
US5922753AJul 13, 1999

Methods for treating bone deficit conditions with benzothiazole

ZYMOGENETICS INC101 citations98
US5843725ADec 1, 1998

Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions

ZYMOGENETICS INC179 citations98
US5833982ANov 10, 1998

Modified factor VII

ZYMOGENETICS INC133 citations98
US5824639AOct 20, 1998

Modified factor VII anticoagulant proteins

ZYMOGENETICS INC111 citations98
US5736383AApr 7, 1998

Preparation of Pichia methanolica auxotrophic mutants

ZYMOGENETICS INC117 citations98
US5288629AFeb 22, 1994

DNA sequence encoding Factor VII with an amino acid substitution at Avg-152

ZYMOGENETICS INC156 citations98
US10434173B2Oct 8, 2019

Use of IL-31 monoclonal antibodies for treating pruritus

ZYMOGENETICS INC49 citations97
US9878038B2Jan 30, 2018

Methods of treating atopic dermatitis with IL-31 monoclonal antibodies

ZYMOGENETICS INC55 citations97
US9624296B2Apr 18, 2017

Polynucleotides encoding IL-31 monoclonal antibodies

ZYMOGENETICS INC51 citations97
US9011858B2Apr 21, 2015

Variable region sequences of IL-31 monoclonal antibodies and methods of use

ZYMOGENETICS INC62 citations97
US8017122B2Sep 13, 2011

Methods of using IL-31 monoclonal antibodies to reduce inflammation

ZYMOGENETICS INC69 citations97
US7790862B2Sep 7, 2010

IL-17 and IL-23 antagonists and methods of using the same

ZYMOGENETICS INC49 citations97
US6485938B1Nov 26, 2002

Nucleic acid molecules that encodes human Zven1

ZYMOGENETICS INC65 citations97
US6468543B1Oct 22, 2002

Methods for promoting growth of bone using ZVEGF4

ZYMOGENETICS INC72 citations97
US6342514B1Jan 29, 2002

Compositions and methods for treating bone deficit conditions

ZYMOGENETICS INC94 citations97
US5965573AOct 12, 1999

Compositions and methods for treating bone deficit conditions

ZYMOGENETICS INC119 citations97
US5919808AJul 6, 1999

Compositions and methods for treating bone deficit conditions

ZYMOGENETICS INC133 citations97
US5817788AOct 6, 1998

Modified factor VII

ZYMOGENETICS INC121 citations97
US5750375AMay 12, 1998

Methods of producing secreted receptor analogs and biologically active dimerized polypeptide fusions

ZYMOGENETICS INC95 citations97
US5567584AOct 22, 1996

Methods of using biologically active dimerized polypeptide fusions to detect PDGF

ZYMOGENETICS INC122 citations97
US5155027AOct 13, 1992

Method of producing secreted receptor analogs and biologically active peptide dimers

ZYMOGENETICS INC211 citations97
US8637015B2Jan 28, 2014

Methods of antagonizing signal transduction in dorsal root ganglion cells

ZYMOGENETICS INC23 citations96

Showing the top 50 of 618 patents by PatentIndex Score.