Assignee
HOFFMANN LA ROCHE
4,619 granted patents·1,303 pending applications·77,376 citations·filing 1968–2025
Top patents by PatentIndex Score
5,922 records- 0199US5602661AOptical componentHOFFMANN LA ROCHE·Filed 1994·Granted Feb 11, 1997·410 cites·19 claims
- 0299US5310652AReverse transcription with thermostable DNA polymerase-high temperature reverse transcriptionHOFFMANN LA ROCHE·Filed 1993·Granted May 10, 1994·386 cites·7 claims
- 0399US4407752AAzeto-imidazo-diazepinesHOFFMANN LA ROCHE·Filed 1982·Granted Oct 4, 1983·65 cites·2 claims
- 0499US4405517AAzeto-diazepinesHOFFMANN LA ROCHE·Filed 1982·Granted Sep 20, 1983·64 cites·3 claims
- 0599US4391731AHydrogenated naphthalenesHOFFMANN LA ROCHE·Filed 1981·Granted Jul 5, 1983·143 cites·15 claims
- 0699US4382032ADiazepine derivativesHOFFMANN LA ROCHE·Filed 1982·Granted May 3, 1983·64 cites·1 claims
- 0798US5747646APolyethylene-protein conjugatesHOFFMANN LA ROCHE·Filed 1995·Granted May 5, 1998·300 cites·12 claims
- 0898US5487972ANucleic acid detection by the 5'-3'exonuclease activity of polymerases acting on adjacently hybridized oligonucleotidesHOFFMANN LA ROCHE·Filed 1993·Granted Jan 30, 1996·855 cites·32 claims
- 0998US5210015AHomogeneous assay system using the nuclease activity of a nucleic acid polymeraseHOFFMANN LA ROCHE·Filed 1990·Granted May 11, 1993·2.1k cites·38 claims
- 1098US5037825ACondensed heterocyclic compoundsHOFFMANN LA ROCHE·Filed 1989·Granted Aug 6, 1991·170 cites·24 claims
- 1198US4859229A3-Aryluracils having an ether (thio) carbomyloxy or sulphomyloxy substituent on the aromatic moietyHOFFMANN LA ROCHE·Filed 1987·Granted Aug 22, 1989·102 cites·36 claims
- 1298US4676604ALiquid crystalsHOFFMANN LA ROCHE·Filed 1984·Granted Jun 30, 1987·72 cites·24 claims
- 1398US4565425ALiquid crystalsHOFFMANN LA ROCHE·Filed 1984·Granted Jan 21, 1986·71 cites·5 claims
- 1498US4512924APyridazo[1,2-a][1,2]diazepinesHOFFMANN LA ROCHE·Filed 1983·Granted Apr 23, 1985·147 cites·28 claims
- 1598US4353827ADiazepine derivativesHOFFMANN LA ROCHE·Filed 1982·Granted Oct 12, 1982·73 cites·21 claims
- 1698US4326055AStilbene derivativesHOFFMANN LA ROCHE·Filed 1978·Granted Apr 20, 1982·278 cites·47 claims
- 1798US4289690AProtein purification process and productHOFFMANN LA ROCHE·Filed 1980·Granted Sep 15, 1981·145 cites·9 claims
- 1898US4280957AImidazodiazepines and processes thereforHOFFMANN LA ROCHE·Filed 1978·Granted Jul 28, 1981·72 cites·5 claims
- 1998US4124598APsoralensHOFFMANN LA ROCHE·Filed 1976·Granted Nov 7, 1978·118 cites·5 claims
- 2097US11673945B2Bispecific antigen binding proteinsHOFFMANN LA ROCHE·Filed 2020·Granted Jun 13, 2023·4 cites·9 claims
- 2197US11482320B2Transformation of digital pathology imagesHOFFMANN LA ROCHE·Filed 2020·Granted Oct 25, 2022·6 cites·13 claims
- 2297US11306154B2Methods of treating cancer by administering antigen-binding molecules comprising a TNF family ligand trimerHOFFMANN LA ROCHE·Filed 2019·Granted Apr 19, 2022·13 cites·56 claims
- 2397US11267903B2Antigen-binding molecules comprising a tumor necrosis factor (TNF) family ligand trimerHOFFMANN LA ROCHE·Filed 2019·Granted Mar 8, 2022·17 cites·46 claims
- 2497US10464981B2Tumor necrosis factor (TNF) family ligand trimer-containing antigen binding moleculesHOFFMANN LA ROCHE·Filed 2016·Granted Nov 5, 2019·33 cites·22 claims
- 2597US10323089B2Anti-transferrin receptor antibodies with tailored affinityHOFFMANN LA ROCHE·Filed 2017·Granted Jun 18, 2019·25 cites·9 claims
- 2697US9969754B2Compounds for treating spinal muscular atrophyHOFFMANN LA ROCHE·Filed 2016·Granted May 15, 2018·25 cites·38 claims
- 2797US9802944B2Bicyclic compounds as autotaxin (ATX) and lysophosphatidic acid (LPA) production inhibitorsHOFFMANN LA ROCHE·Filed 2016·Granted Oct 31, 2017·20 cites·23 claims
- 2897US7851626B24,4,5,5, tetrasubstituted imidazolinesHOFFMANN LA ROCHE·Filed 2006·Granted Dec 14, 2010·43 cites·33 claims
- 2997US7563441B2Anti-P-selectin antibodiesHOFFMANN LA ROCHE·Filed 2005·Granted Jul 21, 2009·94 cites·34 claims
- 3097US7495007B2Spiroindolinone derivativesHOFFMANN LA ROCHE·Filed 2007·Granted Feb 24, 2009·37 cites·45 claims
- 3197US7014866B2High dose solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate and process for making sameHOFFMANN LA ROCHE·Filed 2002·Granted Mar 21, 2006·151 cites·29 claims
- 3297US6756364B2Method of reducing gastrointestinal side effects associated with orlistat treatmentHOFFMANN LA ROCHE·Filed 2001·Granted Jun 29, 2004·129 cites·1 claims
- 3397US6727261B2Pyrido[2,1-A]Isoquinoline derivativesHOFFMANN LA ROCHE·Filed 2002·Granted Apr 27, 2004·184 cites·17 claims
- 3497US6660721B2Anti-HCV nucleoside derivativesHOFFMANN LA ROCHE·Filed 2002·Granted Dec 9, 2003·208 cites·3 claims
- 3597US6610846B1Heteroaromatic glucokinase activatorsHOFFMANN LA ROCHE·Filed 2000·Granted Aug 26, 2003·93 cites·28 claims
- 3697US6320050B1Heteroaromatic glucokinase activatorsHOFFMANN LA ROCHE·Filed 2000·Granted Nov 20, 2001·105 cites·216 claims
- 3797US6039975AColon targeted delivery systemHOFFMANN LA ROCHE·Filed 1996·Granted Mar 21, 2000·522 cites·14 claims
- 3897US5849860APolyethylene-protein conjugatesHOFFMANN LA ROCHE·Filed 1995·Granted Dec 15, 1998·221 cites·3 claims
- 3997US5834594APolyethylene-protein conjugatesHOFFMANN LA ROCHE·Filed 1995·Granted Nov 10, 1998·262 cites·5 claims
- 4097US5705062AAnalytical device for separating magnetic microparticles from suspensionsHOFFMANN LA ROCHE·Filed 1994·Granted Jan 6, 1998·224 cites·15 claims
- 4197US5618711ARecombinant expression vectors and purification methods for Thermus thermophilus DNA polymeraseHOFFMANN LA ROCHE·Filed 1995·Granted Apr 8, 1997·301 cites·11 claims
- 4297US5559213APolyethylene-protein conjugatesHOFFMANN LA ROCHE·Filed 1995·Granted Sep 24, 1996·204 cites·4 claims
- 4397US5455178AMicrooptical sensor and methodHOFFMANN LA ROCHE·Filed 1993·Granted Oct 3, 1995·294 cites·21 claims
- 4497US5389698AProcess for making photopolymers having varying molecular orientation using light to orient and polymerizeHOFFMANN LA ROCHE·Filed 1993·Granted Feb 14, 1995·274 cites·3 claims
- 4597US5333675AApparatus and method for performing automated amplification of nucleic acid sequences and assays using heating and cooling stepsHOFFMANN LA ROCHE·Filed 1993·Granted Aug 2, 1994·465 cites·57 claims
- 4697US5319478ALight control systems with a circular polarizer and a twisted nematic liquid crystal having a minimum path difference of λ/2HOFFMANN LA ROCHE·Filed 1990·Granted Jun 7, 1994·282 cites·12 claims
- 4797US5157041AAmino acid derivativesHOFFMANN LA ROCHE·Filed 1989·Granted Oct 20, 1992·117 cites·19 claims
- 4897US5057614ASubstituted pyrrolesHOFFMANN LA ROCHE·Filed 1989·Granted Oct 15, 1991·208 cites·12 claims
- 4997US5041266ATray for immunometric determinationsHOFFMANN LA ROCHE·Filed 1989·Granted Aug 20, 1991·193 cites·2 claims
- 5097US4959361ATriazolo(4,3-A)(1,4)benzodiazepines and thieno (3,2-F)(1,2,4)triazolo(4,3-A)(1,4)diazepine compounds which have useful activity as platelet activating factor (PAF) antagonistsHOFFMANN LA ROCHE·Filed 1988·Granted Sep 25, 1990·83 cites·64 claims
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