Inventor

WITTRUP KARL DANE

US29 patents

⚠️ This page may combine multiple inventors who share the name “WITTRUP KARL DANE”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

WITTRUP KARL DANE

MASSACHUSETTS INST TECHNOLOGY

Mutant interleukin-2 (IL-2) polypeptides

Synergistic tumor treatment with antibodies targeting PD-1, PD-L1 or CTLA4 and integrin-binding-Fc-fusion protein

Synergistic tumor treatment with extended-PK IL-2 and therapeutic agents

Methods to specifically profile protease activity at lymph nodes

Methods of treating cancer cells expressing tumor-associated integrins

Monoclonal antibodies that bind human CD161

Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof

Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy

Synthetic oncolytic LNP-replicon RNA and uses for cancer immunotherapy

Immunomodulatory fusion protein-metal hydroxide complexes and methods thereof

Combination immunotherapy for treatment of melanoma, colon or non-small cell lung cancers

Combination immunotherapy dosing regimen for immune checkpoint blockade

Collagen-localized immunomodulatory molecules and methods thereof

Multiple specificity binders of CXC chemokines

Methods of activating anti-CD19 chimeric antigen receptor (CAR) T cells using amphiphilic ligand conjugates comprising CAR-targeting protein sequence motifs

ADIMAB LLC

Polyclonal mixtures of antibodies, and methods of making and using them

Polyclonal mixtures of antibodies, and methods of making and using them

Polyclonal mixtures of antibodies, and methods of making and using them

Nodus Therapeutics

Method of treating cancer with a multiple integrin binding Fc fusion protein

Combination tumor treatment with an integrin-binding-Fc fusion protein and immune stimulator

MEMORIAL SLOAN KETTERING CANCER CENTER

Multi-specific antibodies with affinity for human A33 antigen and DOTA metal complex and uses thereof

Multi-specific antibodies with affinity for human A33 antigen and DOTA metal complex and uses thereof

RES CORP TECHNOLOGIES INC

Methods for increasing secretion of overexpressed proteins

DAVIS ORCUTT KELLY

Engineered proteins with high affinity for DOTA chelates

UNIV LELAND STANFORD JUNIOR

Synergistic tumor treatment with an extended pharmacokinetic IL-2 and integrin-binding-Fc fusion protein

PEELLE BEAU R

Cell display libraries

FRED HUTCHINSON CANCER CENTER

Bispecific antibodies specific for treating hematological malignancies

ANKYRA THERAPEUTICS INC

Fusion polypeptides comprising interleukin 12 and a metal-hydroxide binding polypeptide

WITTRUP KARL DANE

Antibody-based constructs directed against tyrosine kinase receptors