Inventor
BRANDS KAREL M J
US12 patents
Patents
12 patentsUS7145002B2Dec 5, 2006
Crystalline forms of carbapenem antibiotics and methods of preparation
MERCK & CO INC43 citations93
US6180783B1Jan 30, 2001
Stabilized carbapenem intermediates and improved process for carbapenem synthesis
MERCK & CO INC21 citations92
US5965747AOct 12, 1999
Crystalline forms of antibiotic side chain intermediates
MERCK & CO INC12 citations72
US6504027B1Jan 7, 2003
Decarboxylation process for synthesizing carbapenem antibiotics
MERCK & CO INC12 citations71
US6063931AMay 16, 2000
Process for synthesizing carbapenem side chain intermediates
MERCK & CO INC14 citations71
US6060607AMay 9, 2000
Process for synthesizing carbapenem side chain intermediates
MERCK & CO INC13 citations71
US6552239B1Apr 22, 2003
Synthesis of cyclopropaneacetylene by a one-pot process
MERCK & CO INC4 citations61
US5721368AFeb 24, 1998
Process for synthesizing carbapenem side chain intermediates
MERCK & CO INC3 citations61
US5648501AJul 15, 1997
Process for synthesizing carbapenem side chain intermediates
MERCK & CO INC6 citations61
USRE40794EJun 23, 2009
Crystalline forms of carbapenem antibiotics and methods of preparation
MERCK & CO INC2 citations59
US6313364B1Nov 6, 2001
Synthesis of cyclopropaneacetylene using a catalytic decarboxylation reaction
MERCK & CO INC1 citations51
US5877328AMar 2, 1999
Process for synthesizing carbapenem side chain intermediates
MERCK & CO INC1 citations51