Inventor
BREAKEFIELD XANDRA O
US29 patents
⚠️ This page may combine multiple inventors who share the name “BREAKEFIELD XANDRA O”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
GEN HOSPITAL CORP
16 patentsUS5501979AMar 26, 1996
Herpes simplex virus type I expression vector
GEN HOSPITAL CORP138 citations96
US5688773ANov 18, 1997
Method of selectively destroying neoplastic cells
GEN HOSPITAL CORP78 citations93
US6610287B1Aug 26, 2003
Transfer and expression of gene sequences into nervous system cells using herpes simplex virus mutants with deletions in genes for viral replication
GEN HOSPITAL CORP26 citations92
US5407821AApr 18, 1995
Genetic diagnosis of torsion dystonia
GEN HOSPITAL CORP23 citations91
US6387616B1May 14, 2002
Torsin, torsin genes, and methods of use
GEN HOSPITAL CORP21 citations88
US6573090B1Jun 3, 2003
Enhanced packaging of herpes virus amplicons and generation of recombinant virus vectors
GEN HOSPITAL CORP44 citations87
US6677155B1Jan 13, 2004
Triple hybrid amplicon vector systems to generate retroviral packaging lines
GEN HOSPITAL CORP17 citations78
US6673602B1Jan 6, 2004
Herpes simplex virus amplicon vector targeting system and method of using same
GEN HOSPITAL CORP13 citations77
US6770632B1Aug 3, 2004
Folypolyglutamyl synthetase gene transfer to enhance antifolate
GEN HOSPITAL CORP18 citations75
US6602499B1Aug 5, 2003
Combination viral-based and gene-based therapy of tumors
GEN HOSPITAL CORP8 citations73
US6262250B1Jul 17, 2001
Kits for detecting polymorphisms associated with familial dysautonomia
GEN HOSPITAL CORP6 citations71
US5998133ADec 7, 1999
Use of genetic markers to diagnose familial dysautonomia
GEN HOSPITAL CORP8 citations71
US5783680AJul 21, 1998
Genetic diagnosis and treatment for impulsive aggression
GEN HOSPITAL CORP12 citations66
US6555108B1Apr 29, 2003
Implanting HSV-TK retrovirus producing cells to treat tumors
GEN HOSPITAL CORP5 citations60
US6537541B1Mar 25, 2003
Implantation of HSV-TK retrovirus producer cells to destroy glioma
GEN HOSPITAL CORP6 citations60
US6921814B2Jul 26, 2005
Torsin, torsin-related genes and methods of detecting neuronal disease
GEN HOSPITAL CORP1 citations48
MASSACHUSETTS GEN HOSPITAL
8 patentsUS9829483B2Nov 28, 2017
Methods of isolating extracellular vesicles
MASSACHUSETTS GEN HOSPITAL7 citations79
US9644215B2May 9, 2017
AAV1-caspase gene therapy induced pyroptosis for the treatment of tumors
MASSACHUSETTS GEN HOSPITAL6 citations78
US10793914B2Oct 6, 2020
Cancer-related biological materials in microvesicles
MASSACHUSETTS GEN HOSPITAL3 citations71
US11519036B2Dec 6, 2022
Use of microvesicles in analyzing nucleic acid profiles
MASSACHUSETTS GEN HOSPITAL0 citations61
US10407728B2Sep 10, 2019
Use of microvesicles in analyzing nucleic acid profiles
MASSACHUSETTS GEN HOSPITAL1 citations61
US11866783B2Jan 9, 2024
Extracellular mRNA markers of muscular dystrophies in human urine
MASSACHUSETTS GEN HOSPITAL1 citations58
US11155874B2Oct 26, 2021
Use of microvesicles in analyzing mutations
MASSACHUSETTS GEN HOSPITAL0 citations51
US9879254B2Jan 30, 2018
Targeting RNAs to microvesicles
MASSACHUSETTS GEN HOSPITAL0 citations41