Inventor

FRENDEWEY DAVID

US56 patents

⚠️ This page may combine multiple inventors who share the name “FRENDEWEY DAVID”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

FRENDEWEY DAVID

REGENERON PHARMA

Methods and compositions for the targeted modification of a genome

MiRNA-regulated differentiation-dependent self-deleting cassette

Method for making homozygous genetic modifications

Method for making genetic modifications

Method for generating an animal homozygous for a genetic modification

miRNA-regulated differentiation-dependent self-deleting cassette

Methods and compositions for the targeted modification of a mouse embryonic stem cell genome

Methods and compositions for the targeted modification of a mouse genome

Genetic modification of rats

Method for genetically modifying isolated non-human mammalian cell by homologous recombination

Methods and compositions for generating a mouse

Methods and compositions for generating a mouse

Methods and compositions for generating a mouse

Promoter-regulated differentiation-dependent self-deleting cassette

Promoter-regulated differentiation-dependent self-deleting cassette

Methods and compositions for the targeted modification of a mouse ES cell genome

Nuclease-mediated targeting with large targeting vectors

Nuclease-mediated targeting with large targeting vectors

Promoter-regulated differentiation-dependent self-deleting cassette

Methods and compositions for modifying a targeted locus

Methods for producing a mouse XY embryonic (ES) cell line capable of producing a fertile XY female mouse in an F0 generation

MiRNA-regulated differentiation-dependent self-deleting cassette

miRNA-regulated differentiation-dependent self-deleting cassette

Production of fertile XY female animals from XY ES cells

Non-human animals having a hexanucleotide repeat expansion in a C9ORF72 locus

Methods and compositions for targeted genetic modification using paired guide RNAs

Compositions and methods for modifying cells

Genetic modification of rats

Methods and compositions for modifying a targeted locus

Markers of tumor cell response to anti-cancer therapy

Methods and compositions for targeted genetic modifications and methods of use

Production of fertile XY female mice from XY mouse ES cells

Production of fertile XY female animals from XY ES cells

Models of tauopathy

Models of tauopathy

Methods and compositions for the targeted modification of a genome

Genetic modification of rats

Methods and compositions for targeted genetic modification using paired guide RNAs

Methods and compositions for modifying a targeted locus

Method for screening gene expression in lincRNA-deficient mice or rats

Methods and compositions for assessing CRISPER/Cas-mediated disruption or excision and CRISPR/Cas-induced recombination with an exogenous donor nucleic acid in vivo

Models of tauopathy

Production of fertile XY female animals by silencing of genes on the Y chromosome

Production of fertile XY female animals by silencing of genes on the Y chromosome

Mouse comprising a humanized TTR locus with a beta-slip mutation and methods of use

ECONOMIDES ARIS N

Method for genetically modifying mouse embryonic stem cell by homologous recombination

Method for detecting the replacement of an endogenous allele with a modified allele by homologous recombination in a mouse ES cell

FRENDEWEY DAVID

Promoter-regulated differentiation-dependent self-deleting cassette

POUEYMIROU WILLIAM

Conditioned culture media

AUERBACH WOJTEK

Production of fertile XY animals from XY ES cells