Inventor
GRUBER JOHN M
US39 patents
⚠️ This page may combine multiple inventors who share the name “GRUBER JOHN M”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
CODEXIS INC
22 patentsUS7820421B2Oct 26, 2010
Ketoreductases and uses thereof
CODEXIS INC37 citations96
US7132267B2Nov 7, 2006
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives and vicinal cyano, hydroxy substituted carboxylic acid esters
CODEXIS INC60 citations94
US7125693B2Oct 24, 2006
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
CODEXIS INC57 citations94
US8852909B2Oct 7, 2014
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC13 citations92
US8512973B2Aug 20, 2013
Methods of using engineered ketoreductase polypeptides for the stereoselective reduction of acetophenones
CODEXIS INC18 citations92
US11512332B2Nov 29, 2022
Engineered ketoreductase polypeptides
CODEXIS INC4 citations84
US10752926B2Aug 25, 2020
Engineered ketoreductase polypeptides
CODEXIS INC3 citations84
US10006069B2Jun 26, 2018
Engineered ketoreductase polypeptides
CODEXIS INC6 citations84
US9951318B1Apr 24, 2018
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC4 citations84
US9873863B2Jan 23, 2018
Polynucleotides encoding ketoreductase polypeptides for reduction of acetophenones
CODEXIS INC5 citations84
US9657320B2May 23, 2017
Engineered ketoreductase polypeptides
CODEXIS INC7 citations84
US9528131B2Dec 27, 2016
Methods of using ketoreductase polypeptides for reduction of acetophenones
CODEXIS INC5 citations84
US9228213B2Jan 5, 2016
Polynucleotides encoding engineered ketoreductase polypeptides
CODEXIS INC5 citations84
US10100288B2Oct 16, 2018
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC3 citations82
US10927351B2Feb 23, 2021
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC1 citations73
US10227572B2Mar 12, 2019
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC2 citations73
US12415990B2Sep 16, 2025
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC0 citations62
US12365927B2Jul 22, 2025
Engineered ketoreductase polypeptides
CODEXIS INC0 citations62
US11479756B2Oct 25, 2022
Ketoreductase polypeptides for the reduction of acetophenones
CODEXIS INC0 citations62
US8673607B2Mar 18, 2014
Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
CODEXIS INC2 citations62
US8980605B2Mar 17, 2015
Ketoreductases and uses thereof
CODEXIS INC0 citations52
US7807423B2Oct 5, 2010
Enzymatic processes for the production of 4-substituted 3-hydroxybutyric acid derivatives
CODEXIS INC0 citations51
SAVILE CHRISTOPHER
3 patentsUS8288141B2Oct 16, 2012
Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
SAVILE CHRISTOPHER27 citations95
US8877475B2Nov 4, 2014
Polynucleotides encoding engineered ketoreductase polypeptides
SAVILE CHRISTOPHER5 citations83
US8426178B2Apr 23, 2013
Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine
SAVILE CHRISTOPHER11 citations83
CATALYTICA INC
3 patentsSANDOZ LTD
3 patentsLIANG JACK
2 patentsCHING CHARLENE
2 patentsCATALYTICA PHARMACEUTICALS INC
2 patentsMIJTS BENJAMIN
2 patentsUS8178333B2May 15, 2012
Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds
MIJTS BENJAMIN3 citations58
US8574876B2Nov 5, 2013
Biocatalytic processes for the preparation of stereomerically pure fused bicyclic proline compounds
MIJTS BENJAMIN0 citations48