Inventor
DOWNES MICHAEL
US46 patents
⚠️ This page may combine multiple inventors who share the name “DOWNES MICHAEL”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SALK INST FOR BIOLOGICAL STUDI
32 patentsUS8999929B2Apr 7, 2015
Fibroblast growth factor 1 protein fragments and methods of use
SALK INST FOR BIOLOGICAL STUDI57 citations95
US9072708B2Jul 7, 2015
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI19 citations92
US8906854B2Dec 9, 2014
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI20 citations92
US6673587B1Jan 6, 2004
Histone deacetylase, and uses therefor
SALK INST FOR BIOLOGICAL STUDI30 citations89
US10077268B2Sep 18, 2018
FXR agonists and methods for making and using
SALK INST FOR BIOLOGICAL STUDI9 citations83
US9925241B2Mar 27, 2018
Mutated fibroblast growth factor (FGF) 1 and methods of use
SALK INST FOR BIOLOGICAL STUDI6 citations83
US9808508B2Nov 7, 2017
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI5 citations83
US9446097B2Sep 20, 2016
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI8 citations83
US9938234B2Apr 10, 2018
PPAR agonists
SALK INST FOR BIOLOGICAL STUDI13 citations82
US10398759B2Sep 3, 2019
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI1 citations72
US10293027B2May 21, 2019
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI2 citations72
US10159711B2Dec 25, 2018
Methods for treating metabolic disorders using FGF
SALK INST FOR BIOLOGICAL STUDI2 citations72
US9872866B2Jan 23, 2018
Vitamin D receptor/SMAD genomic circuit gates fibrotic response
SALK INST FOR BIOLOGICAL STUDI2 citations72
US11376264B2Jul 5, 2022
Use of bromodomain-containing protein 9 antagonists in combination with vitamin D receptor agonists in diabetes treatment
SALK INST FOR BIOLOGICAL STUDI3 citations71
US10301268B2May 28, 2019
Analogs of fexaramine and methods of making and using
SALK INST FOR BIOLOGICAL STUDI4 citations71
US10539572B2Jan 21, 2020
Compositions and methods for treating age-related diabetes and related disorders
SALK INST FOR BIOLOGICAL STUDI1 citations69
US9925243B2Mar 27, 2018
Chimeric fibroblast growth factor (FGF) 2/FGF1 peptides and methods of use
SALK INST FOR BIOLOGICAL STUDI5 citations69
US10920199B2Feb 16, 2021
Reprogramming progenitor compositions and methods of use therefore
SALK INST FOR BIOLOGICAL STUDI4 citations68
US9895381B2Feb 20, 2018
Vitamin D receptor agonists to treat diseases involving CXCL12 activity
SALK INST FOR BIOLOGICAL STUDI2 citations67
US10695404B2Jun 30, 2020
Treatment of steroid-induced hyperglycemia with fibroblast growth factor (FGF) 1 analogs
SALK INST FOR BIOLOGICAL STUDI1 citations62
US11440889B2Sep 13, 2022
Analogs of fexaramine and methods of making and using
SALK INST FOR BIOLOGICAL STUDI0 citations61
US10550071B2Feb 4, 2020
PPAR agonists
SALK INST FOR BIOLOGICAL STUDI1 citations61
US12253527B2Mar 18, 2025
Compositions and methods for treating age-related diabetes and related disorders
SALK INST FOR BIOLOGICAL STUDI0 citations59
US11428697B2Aug 30, 2022
Compositions and methods for treating age-related diabetes and related disorders
SALK INST FOR BIOLOGICAL STUDI0 citations59
US11420934B2Aug 23, 2022
PPAR agonists
SALK INST FOR BIOLOGICAL STUDI0 citations59
US11760977B2Sep 19, 2023
Compositions and methods for organoid generation and disease modeling
SALK INST FOR BIOLOGICAL STUDI0 citations58
US11685901B2Jun 27, 2023
Compositions and methods for organoid generation and disease modeling
SALK INST FOR BIOLOGICAL STUDI1 citations58
US11542309B2Jan 3, 2023
Fibroblast growth factor 1 (FGF1) mutant proteins that selectively activate FGFR1B to reduce blood glucose
SALK INST FOR BIOLOGICAL STUDI0 citations58
US11981931B2May 14, 2024
Reprogramming progenitor compositions and methods of use thereof
SALK INST FOR BIOLOGICAL STUDI0 citations57
US10815203B2Oct 27, 2020
Analogs of fexaramine and methods of making and using
SALK INST FOR BIOLOGICAL STUDI0 citations50
US10450277B2Oct 22, 2019
Analogs of fexaramine and methods of making and using
SALK INST FOR BIOLOGICAL STUDI0 citations50
US10238667B2Mar 26, 2019
Vitamin D receptor/SMAD genomic circuit gates fibrotic response
SALK INST FOR BIOLOGICAL STUDI0 citations49
MITOBRIDGE INC
5 patentsUS10479775B1Nov 19, 2019
PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
MITOBRIDGE INC7 citations83
US10399958B2Sep 3, 2019
PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
MITOBRIDGE INC7 citations83
US11578052B2Feb 14, 2023
PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
MITOBRIDGE INC1 citations72
US10906885B2Feb 2, 2021
PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
MITOBRIDGE INC1 citations72
US10188627B2Jan 29, 2019
PPAR agonists, compounds, pharmaceutical compositions, and methods of use thereof
MITOBRIDGE INC0 citations40
SALK INST BIOLOGICAL STUDIES
3 patentsUS10035819B2Jul 31, 2018
PPAR agonists and methods of use thereof
SALK INST BIOLOGICAL STUDIES13 citations83
US11130779B2Sep 28, 2021
PPAR agonists and methods of use thereof
SALK INST BIOLOGICAL STUDIES0 citations62
US10550149B2Feb 4, 2020
PPAR agonists and methods of use thereof
SALK INST BIOLOGICAL STUDIES0 citations51