Inventor
PASTAN IRA H
US71 patents
⚠️ This page may combine multiple inventors who share the name “PASTAN IRA H”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
US HEALTH
29 patentsUS5747654AMay 5, 1998
Recombinant disulfide-stabilized polypeptide fragments having binding specificity
US HEALTH140 citations98
US4892827AJan 9, 1990
Recombinant pseudomonas exotoxins: construction of an active immunotoxin with low side effects
US HEALTH180 citations97
US7368110B2May 6, 2008
Antibodies, including Fv molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
US HEALTH38 citations96
US7355012B2Apr 8, 2008
Mutated anti-CD22 antibodies with increased affinity to CD22-expressing leukemia cells
US HEALTH99 citations96
US6809184B1Oct 26, 2004
Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
US HEALTH69 citations96
US7982011B2Jul 19, 2011
Mutated anti-cd22 antibodies and immunoconjugates
US HEALTH57 citations95
US7521054B2Apr 21, 2009
Reduction of the nonspecific animal toxicity of immunotoxins by mutating the framework regions of the Fv to lower the isoelectric point
US HEALTH72 citations95
US6558672B1May 6, 2003
Methods of making recombinant disulfide-stabilized polypeptide fragments having binding specificity
US HEALTH68 citations95
US6147203ANov 14, 2000
Recombinant disulfide-stabilized polypeptide fragments having binding specificity
US HEALTH70 citations95
US6051405AApr 18, 2000
Constructs encoding recombinant antibody-toxin fusion proteins
US HEALTH56 citations95
US5863745AJan 26, 1999
Recombinant antibody-toxin fusion protein
US HEALTH65 citations95
US5696237ADec 9, 1997
Recombinant antibody-toxin fusion protein
US HEALTH91 citations95
US5635599AJun 3, 1997
Fusion proteins comprising circularly permuted ligands
US HEALTH72 citations95
US5082927AJan 21, 1992
Selectively cytotoxic IL-4-PE40 fusion protein
US HEALTH58 citations95
US9868774B2Jan 16, 2018
Anti-CD22 chimeric antigen receptors
US HEALTH36 citations93
US9359447B2Jun 7, 2016
Anti-mesothelin chimeric antigen receptors
US HEALTH44 citations93
US9416190B2Aug 16, 2016
Mesothelin antibodies and methods for eliciting potent antitumor activity
US HEALTH31 citations92
US8357783B2Jan 22, 2013
Human anti-mesothelin monoclonal antibodies
US HEALTH22 citations92
US7709252B2May 4, 2010
Antibodies, including FV molecules, and immunoconjugates having high binding affinity for mesothelin and methods for their use
US HEALTH13 citations92
US7470775B2Dec 30, 2008
Anti-CD30 stalk and anti-CD30 antibodies suitable for use in immunotoxins
US HEALTH18 citations90
US10072078B2Sep 11, 2018
M971 chimeric antigen receptors
US HEALTH7 citations84
US9279019B2Mar 8, 2016
Human monoclonal antibodies specific for CD22
US HEALTH10 citations84
US7910692B2Mar 22, 2011
Immunogenic peptides and methods of use
US HEALTH7 citations84
US9388222B2Jul 12, 2016
Modified Pseudomonas exotoxin A
US HEALTH15 citations83
US9803022B2Oct 31, 2017
Mesothelin domain-specific monoclonal antibodies and use thereof
US HEALTH15 citations82
US9409992B2Aug 9, 2016
Mesothelin domain-specific monoclonal antibodies and use thereof
US HEALTH16 citations82
US10703816B2Jul 7, 2020
M971 chimeric antigen receptors
US HEALTH3 citations73
US10925969B2Feb 23, 2021
Anti-BCMA polypeptides and proteins
US HEALTH6 citations71
US11807682B2Nov 7, 2023
M971 chimeric antigen receptors
US HEALTH0 citations62
PASTAN IRA H
6 patentsUS8871906B2Oct 28, 2014
Deletions in domain II of pseudomonas exotoxin a that remove immunogenic epitopes
PASTAN IRA H27 citations90
US9206240B2Dec 8, 2015
Pseudomonas exotoxin A with less immunogenic B cell epitopes
PASTAN IRA H8 citations83
US8936792B2Jan 20, 2015
Pseudomonas exotoxin a with reduced immunogenicity
PASTAN IRA H8 citations83
US9346859B2May 24, 2016
Pseudomonas exotoxin A with less immunogenic T cell and/or B cell epitopes
PASTAN IRA H8 citations80
US8907060B2Dec 9, 2014
Mutated Pseudomonas exotoxins with reduced antigenicity
PASTAN IRA H6 citations72
US10683362B2Jun 16, 2020
Recombinant immunotoxin targeting mesothelin
PASTAN IRA H3 citations70
US ARMY
3 patentsUNIV DUKE
3 patentsUS8039593B2Oct 18, 2011
Antibodies and immunotoxins that target human glycoprotein NMB
UNIV DUKE10 citations84
US10072084B2Sep 11, 2018
Dual specific immunotoxin for brain tumor therapy
UNIV DUKE2 citations70
US10053514B2Aug 21, 2018
Human bispecific EGFRvIII and CD3 antibody engaging molecules
UNIV DUKE3 citations69
NAT INST HEALTH
1 patentSCHLOM JEFFREY
1 patentDIMITROV DIMITER S
1 patentUS AS REPRESENTED BY THE DEPAR
1 patentUNIV ILLINOIS
1 patentCETUS CORP
1 patentTHE US SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES
1 patentBIGNER DARELL D
1 patentTHE GOVERNMENT OF THE U S A AS REPRESENTED BY THE SECRETARY OF THE DEPT OF HEALTH AND HUMAN SERVICES
1 patentShowing the top 50 of 71 patents by PatentIndex Score.