Inventor
BAKER BRENDA F
US37 patents
⚠️ This page may combine multiple inventors who share the name “BAKER BRENDA F”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
ISIS PHARMACEUTICALS INC
27 patentsUS7339051B2Mar 4, 2008
Compositions and methods for the treatment of severe acute respiratory syndrome (SARS)
ISIS PHARMACEUTICALS INC158 citations98
US6210892B1Apr 3, 2001
Alteration of cellular behavior by antisense modulation of mRNA processing
ISIS PHARMACEUTICALS INC358 citations98
US8361977B2Jan 29, 2013
Compositions and methods for modulation of SMN2 splicing
ISIS PHARMACEUTICALS INC62 citations97
US7321828B2Jan 22, 2008
System of components for preparing oligonucleotides
ISIS PHARMACEUTICALS INC216 citations96
US6228642B1May 8, 2001
Antisense oligonucleotide modulation of tumor necrosis factor-(α) (TNF-α) expression
ISIS PHARMACEUTICALS INC91 citations96
US6007995ADec 28, 1999
Antisense inhibition of TNFR1 expression
ISIS PHARMACEUTICALS INC88 citations96
US6080580AJun 27, 2000
Antisense oligonucleotide modulation of tumor necrosis factor-α (TNF-α) expression
ISIS PHARMACEUTICALS INC86 citations94
US6171860B1Jan 9, 2001
Antisense inhibition of rank expression
ISIS PHARMACEUTICALS INC18 citations93
US7919612B2Apr 5, 2011
2′-substituted oligomeric compounds and compositions for use in gene modulations
ISIS PHARMACEUTICALS INC14 citations92
US6372433B1Apr 16, 2002
Antisense modulation of inhibitor of DNA binding-1 expression
ISIS PHARMACEUTICALS INC22 citations92
US7884086B2Feb 8, 2011
Conjugates for use in hepatocyte free uptake assays
ISIS PHARMACEUTICALS INC21 citations90
US7812149B2Oct 12, 2010
2′-Fluoro substituted oligomeric compounds and compositions for use in gene modulations
ISIS PHARMACEUTICALS INC12 citations84
US6054316AApr 25, 2000
Antisense inhibition of ETs-2 expression
ISIS PHARMACEUTICALS INC17 citations84
US8946183B2Feb 3, 2015
Compositions and methods for modulation of SMN2 splicing
ISIS PHARMACEUTICALS INC12 citations83
US6159734ADec 12, 2000
Antisense modulation of peroxisome proliferator-activated receptor gamma expression
ISIS PHARMACEUTICALS INC16 citations83
US7790691B2Sep 7, 2010
Double stranded compositions comprising a 3′-endo modified strand for use in gene modulation
ISIS PHARMACEUTICALS INC12 citations82
US6015712AJan 18, 2000
Antisense modulation of FADD expression
ISIS PHARMACEUTICALS INC15 citations74
US6001652ADec 14, 1999
Antisense modulation of cREL expression
ISIS PHARMACEUTICALS INC12 citations74
US5985664ANov 16, 1999
Antisense modulation of Sentrin expression
ISIS PHARMACEUTICALS INC8 citations74
US5962671AOct 5, 1999
Antisense modulation of fan expression
ISIS PHARMACEUTICALS INC6 citations74
US5948680ASep 7, 1999
Antisense inhibition of Elk-1 expression
ISIS PHARMACEUTICALS INC16 citations74
US5643780AJul 1, 1997
Compositions and methods for modulating RNA activity through modification of the 5' cap structure of RNA
ISIS PHARMACEUTICALS INC7 citations74
US6399297B1Jun 4, 2002
Antisense modulation of expression of tumor necrosis factor receptor-associated factors (TRAFs)
ISIS PHARMACEUTICALS INC11 citations70
US6399379B1Jun 4, 2002
Antisense modulation of interleukin 12 p35 subunit expression
ISIS PHARMACEUTICALS INC2 citations63
US6355438B1Mar 12, 2002
Method for quantitating oligonucleotides
ISIS PHARMACEUTICALS INC4 citations61
US7700574B2Apr 20, 2010
Modulation of RANKL expression
ISIS PHARMACEUTICALS INC1 citations50
US6586245B2Jul 1, 2003
Antisense modulation of CD40 ligand expression
ISIS PHARMACEUTICALS INC0 citations40
IONIS PHARMACEUTICALS INC
4 patentsUS10266825B2Apr 23, 2019
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
IONIS PHARMACEUTICALS INC10 citations84
US9708610B2Jul 18, 2017
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
IONIS PHARMACEUTICALS INC6 citations82
US11078485B2Aug 3, 2021
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
IONIS PHARMACEUTICALS INC0 citations62
US9771578B2Sep 26, 2017
Phosphorous-linked oligomeric compounds and their use in gene modulation
IONIS PHARMACEUTICALS INC0 citations52
ALLERSON CHARLES
3 patentsUS8604183B2Dec 10, 2013
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
ALLERSON CHARLES20 citations92
US9150606B2Oct 6, 2015
Compositions comprising alternating 2'-modified nucleosides for use in gene modulation
ALLERSON CHARLES9 citations84
US9150605B2Oct 6, 2015
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation
ALLERSON CHARLES9 citations84