Inventor

GRIFFITH OWEN W

US42 patents

⚠️ This page may combine multiple inventors who share the name “GRIFFITH OWEN W”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

GRIFFITH OWEN W

CORNELL RES FOUNDATION INC

N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body

N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body

Isolating aminoarginine and use to block nitric oxide formation in body

Method of using arginine derivatives to inhibit systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor

Enhancing delivery of large neutral amino acid drugs

Substituted arginines and substituted homoarginines and use thereof

Use of arginase to control nitric oxide formation

Method of using aminoarginine to block nitric oxide formation in vitro

Method for treating systemic hypotension caused by sepsis or cytokine using arginase in combination with an α1 adrenergic agonist

Substituted arginines and substituted homoarginines and use thereof

N6 -(hydrazinoiminomethyl)lysine and method of inhibiting nitric oxide formation in body

Use of arginase to control nitric oxide formation

L-buthionine-S-sulfoximine and methods of making

L-buthionine-S-sulfoximine and L-buthionine-R-sulfoximine

Novel diacylglycerophosphoric acid esters and use thereof as substrates in enzyme assays

Enhancing the anti-tumor effect of melphalan by prior administration of L-amino acid oxidase with or without intermediate administration of anti-L-amino acid oxidase antibody

Enhancing the anti-tumor effect of melphalan with L-amino acid oxidase

Aminocarnitines

Preparing glutathione monoesters

L-buthionine-s-sulfoximine and methods of making

WISCONSIN MED COLLEGE INC

S-alkyl-isothioureido-amino acids and use thereof

Heme binding compounds and use thereof

Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction

Preventing conversion of citrulline to argininosuccinate to limit pathological nitric oxide overproduction

L-N5 -(1-imino-3-alkenyl) ornithine and related compounds and use thereof

Heme binding compounds and use thereof

Method for the treatment of hypotension induced by a cytokine or bacterial endotoxin using s-alkyl- isothioureido-amino acids

Heme binding compounds and use thereof

UNIV TEXAS

Anti-endotoxin, interleukin-1 receptor antagonist and anti-tumor necrosis factor antibody with arginine-free formulations for the treatment of hypotension

Methods and compositions for the treatment of hypotension with arginine free essential and essential amino acids and arginine derivatives

Parenteral formulations for the inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor

Use of cardiotonic drugs and inhibitors of nitric oxide synthesis to alleviate pathologic hypotension

Method of use of cardiotonic drugs and inhibitors of nitric oxide synthesis to alleviate pathologic hypotension

Argine antagonists for inhibition of systemic hypotension associated with nitric oxide production or endothelial derived relaxing factor

Parenteral amino acid formulations for the inhibition of systemic hypotension associated with nitric oxide production

UNIV DUKE

Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses

Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase

Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically, proliferating cells or to upregulate nitrosative stress defenses

Manipulating nitrosative stress to upregulate nitrosative stress defenses

Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses

Manipulating nitrosative stress to kill pathologic microbes, pathologic helminths and pathologically proliferating cells or to upregulate nitrosative stress defenses

UNIV VIRGINIA

Treating asthma by preventing and/or accomodating S-nitrosothiol breakdown