Inventor

ZAMBROWICZ BRIAN

US72 patents

⚠️ This page may combine multiple inventors who share the name “ZAMBROWICZ BRIAN”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

ZAMBROWICZ BRIAN

LEXICON GENETICS INC

Vectors for gene trapping and gene activation

Indexed library of cells containing genomic modifications and methods of making and utilizing the same

Vectors for gene mutagenesis and gene discovery

Indexed library of cells containing genomic modifications and methods of making and utilizing the same

Lipoxygenase proteins and polynucleotides encoding the same

Targeted gene discovery

Human transporter proteins and polynucleotides encoding the same

Human ion channel protein and polynucleotides encoding the same

Human calcium dependent proteases, polynucleotides encoding the same, and uses thereof

Human uncoupling proteins and polynucleotides encoding the same

Vectors for gene mutagenesis and gene discovery

Vectors for gene mutagenesis and gene discovery

Construction of normalized cDNA libraries from eucaryotic cells

Human proteases and polynucleotides encoding the same

Human proteases and polynucleotides encoding the same

Human kinase proteins and polynucleotides encoding the same

Human carboxypeptidases and polynucleotides encoding the same

Human proteases and polynucleotides encoding the same

Human proteases and polynucleotides encoding the same

Human kinase proteins and polynucleotides encoding the same

Human transferase proteins and polynucleotides encoding the same

Human kinase proteins and polynucleotides encoding the same

Human proteases and polynucleotides encoding the same

Human ATPase proteins and polynucleotides encoding the same

Human carboxypeptidases and polynucleotides encoding the same

Human proteases and polynucleotides encoding the same

Human transferase proteins and polynucleotides encoding the same

REGENERON PHARMA

CRISPR/Cas dropout screening platform to reveal genetic vulnerabilities associated with tau aggregation

CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregation

Transcription modulation in animals using CRISPR/Cas systems

Models of tauopathy

Models of tauopathy

Methods and compositions for targeted genetic modification through single-step multiple targeting

Methods and compositions for targeted genetic modification through single-step multiple targeting

CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregation

Transcription modulation in animals using CRISPR/CAS systems

Methods and compositions for assessing CRISPER/Cas-mediated disruption or excision and CRISPR/Cas-induced recombination with an exogenous donor nucleic acid in vivo

CRISPR/Cas screening platform to identify genetic modifiers of tau seeding or aggregation

Models of tauopathy

Cas-ready mouse embryonic stem cells and mice and uses thereof

Rodent model of mood disorders

Cas-ready mouse embryonic stem cells and mice and uses thereof

Method of using a genetically modified mouse that expresses human albumin

Genetically modified mouse that expresses human albumin

Mouse comprising a humanized TTR locus with a beta-slip mutation and methods of use

LEXICON PHARMACEUTICALS INC

Inhibitors of sodium glucose transporter 1 for constipation

Inhibitors of sodium glucose cotransporter 1

Inhibitors of sodium glucose cotransporter 1

Polynucleotides encoding human transporter proteins

LEXICON GENETICS CORP

Human thrombospondin repeat proteins and polynucleotides encoding the same