Inventor
HOFFMANN-EMERY FABIENNE
CH13 patents
Patents
13 patentsUS6531597B2Mar 11, 2003
Process for preparation of 2-phenyl acetic acid derivatives
HOFFMANN LA ROCHE14 citations83
US6303790B1Oct 16, 2001
Process for the preparation of pyridine derivatives
HOFFMANN LA ROCHE16 citations80
US6391873B1May 21, 2002
Imidazodiazepine derivative
HOFFMANN LA ROCHE12 citations71
US11040977B2Jun 22, 2021
Synthesis of trans-8-chloro-5-methyl-1-[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[e]azulene and crytalline forms thereof
HOFFMANN LA ROCHE1 citations70
US10246460B2Apr 2, 2019
Synthesis of trans-8-chloro-5-methyl-1-[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[E]azulene and crytalline forms thereof
HOFFMANN LA ROCHE2 citations70
US11390632B2Jul 19, 2022
Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8-dimethylimidazo [1,2-B]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives
HOFFMANN LA ROCHE3 citations67
US6281353B1Aug 28, 2001
Method of making diazepine derivatives
HOFFMANN LA ROCHE3 citations61
US12459947B2Nov 4, 2025
Synthesis of trans-8-chloro-5-methyl-1 -[4-(pyridin-2-yloxy)-cyclohexyl]-5,6-dihydro-4H-2,3,5,10B-tetraaza-benzo[e]azulene and crystalline forms thereof
HOFFMANN LA ROCHE0 citations59
US12122791B2Oct 22, 2024
Process for the preparation of 7-(4,7-diazaspiro[2.5]octan-7-yl)-2-(2,8- dimethylimidazo[1,2-b]pyridazin-6-yl)pyrido[1,2-a]pyrimidin-4-one derivatives
HOFFMANN LA ROCHE0 citations57
US8344161B2Jan 1, 2013
Process for the preparation of pyrollidine-3-carboxylic acids
HOFFMANN LA ROCHE0 citations51
US7579464B2Aug 25, 2009
Process for preparation of enantiomerically pure compounds
HOFFMANN LA ROCHE0 citations51
US7160881B2Jan 9, 2007
Crystalline modifications of 2-(3,5-bis-trifluoromethyl-phenyl)-N-[6-(1,1-dioxo-1 λ6-thiomorpholin-4-yl)-4-(4-fluoro-2-methyl-phenyl)-pyridin-3-yl]-N-methyl-isobutyramide
HOFFMANN LA ROCHE0 citations47
US10538536B2Jan 21, 2020
Process for the preparation of 2-pyrazolo[1,5-a]pyrazin-2-ylpyrido[1,2-a]pyrimidin-4-one compounds
HOFFMANN LA ROCHE0 citations45