P

Inventor

Coffman jonathan

US13 patents

Patents

13 patents
US11104875B2Aug 31, 2021

Linked perfusion to continuous-flow stirred-tank reactor cell culture system

BOEHRINGER INGELHEIM INT9 citations81
US10435670B2Oct 8, 2019

Methods, apparatuses, and systems for continuously inactivating a virus during manufacture of a biological product

BOEHRINGER INGELHEIM INT6 citations79
US12018290B2Jun 25, 2024

Methods for continuously inactivating a virus during manufacture of a protein

BOEHRINGER INGELHEIM INT2 citations67
US11407981B2Aug 9, 2022

Methods for continuously inactivating a virus during manufacture of a protein

BOEHRINGER INGELHEIM INT3 citations67
US12195712B2Jan 14, 2025

Linked perfusion to continuous-flow stirred-tank reactor cell culture system

BOEHRINGER INGELHEIM INT0 citations58
US12371671B2Jul 29, 2025

Methods for continuously inactivating a virus during manufacture of a protein

BOEHRINGER INGELHEIM INT0 citations57
US11725191B2Aug 15, 2023

Methods, apparatuses, and systems for continuously inactivating a virus during manufacture of a biological product

BOEHRINGER INGELHEIM INT1 citations57
US12435303B2Oct 7, 2025

Continuous flow reactor for low pH viral inactivation

BOEHRINGER INGELHEIM INT0 citations56
US12163118B2Dec 10, 2024

Continuous flow reactor for viral inactivation

BOEHRINGER INGELHEIM INT0 citations56
US12415980B2Sep 16, 2025

Method for membrane gas transfer in high density bioreactor culture

BOEHRINGER INGELHEIM INT0 citations53
US12157877B2Dec 3, 2024

Cell retention device and method

BOEHRINGER INGELHEIM INT0 citations47
US12209257B2Jan 28, 2025

System and method to determine critical process parameters for a continuous viral inactivation reactor to design and manufacture same

BOEHRINGER INGELHEIM INT0 citations46
US12509655B2Dec 30, 2025

Integrated and continuous recombinant protein manufacturing

BOEHRINGER INGELHEIM INT0 citations41