Inventor
SPRUCE LYLE W
US34 patents
⚠️ This page may combine multiple inventors who share the name “SPRUCE LYLE W”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
CORTECH INC
25 patentsUS5861380AJan 19, 1999
Serine protease inhibitors-keto and di-keto containing ring systems
CORTECH INC144 citations99
US6004933ADec 21, 1999
Cysteine protease inhibitors
CORTECH INC159 citations97
US6159938ADec 12, 2000
Serine protease inhibitors comprising α-keto heterocycles
CORTECH INC146 citations96
US5874585AFeb 23, 1999
Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
CORTECH INC28 citations96
US5869455AFeb 9, 1999
Serine protease inhibitors-N-substituted derivatives
CORTECH INC40 citations96
US5807829ASep 15, 1998
Serine protease inhibitor--tripeptoid analogs
CORTECH INC34 citations96
US5801148ASep 1, 1998
Serine protease inhibitors-proline analogs
CORTECH INC34 citations96
US5618792AApr 8, 1997
Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
CORTECH INC63 citations96
US6075120AJun 13, 2000
Bradykinin antagonist
CORTECH INC43 citations93
US6037325AMar 14, 2000
Substituted heterocyclic compounds useful as inhibitors of (serine proteases) human neutrophil elastase
CORTECH INC18 citations92
US6015791AJan 18, 2000
Serine protease inhibitors-cycloheptane derivatives
CORTECH INC26 citations92
US6001813ADec 14, 1999
Val-pro containing α-keto oxadiazoles as serine protease inhibitors
CORTECH INC25 citations92
US6001814ADec 14, 1999
Serine protease inhibitors
CORTECH INC25 citations92
US5843900ADec 1, 1998
Bradykinin antagonists
CORTECH INC31 citations92
US5863899AJan 26, 1999
Bradykinin antagonists
CORTECH INC30 citations90
US5891852AApr 6, 1999
Serine protease inhibitors-cycloheptane derivatives
CORTECH INC14 citations82
US6001811ADec 14, 1999
Serine protease inhibitors--N-substituted derivatives
CORTECH INC16 citations74
US6150334ANov 21, 2000
Serine protease inhibitors-tripeptoid analogs
CORTECH INC13 citations73
US6100238AAug 8, 2000
Indole and tetrahydroisoquinoline containing Alpha-keto oxadiazoles as serine protease inhibitors
CORTECH INC12 citations73
US5663416ASep 2, 1997
Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase
CORTECH INC12 citations73
US5214191AMay 25, 1993
Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase
CORTECH INC12 citations73
US6656911B2Dec 2, 2003
Serine protease inhibitors
CORTECH INC3 citations63
US6608175B2Aug 19, 2003
Serine protease inhibitors
CORTECH INC4 citations63
US5998379ADec 7, 1999
Serine protease inhibitors-proline analogs
CORTECH INC6 citations63
US6656910B2Dec 2, 2003
Serine protease inhibitors
CORTECH INC2 citations52
ORTHO MCNEIL PHARM INC
4 patentsUS6974826B2Dec 13, 2005
Imidazolidinedione derivatives for the treatment of diabetes and other diseases
ORTHO MCNEIL PHARM INC5 citations73
US7196108B2Mar 27, 2007
Bicyclic heterocycles for the treatment of diabetes and other diseases
ORTHO MCNEIL PHARM INC7 citations71
US7071218B2Jul 4, 2006
N-substituted heterocycles for the treatment of hypercholesteremia, dyslipidemia and other metabolic disorders; cancer, and other diseases
ORTHO MCNEIL PHARM INC10 citations70
US7226940B2Jun 5, 2007
Substituted heterocycles for the treatment of diabetes and other diseases
ORTHO MCNEIL PHARM INC3 citations62