Inventor
CONN P JEFFREY
US92 patents
⚠️ This page may combine multiple inventors who share the name “CONN P JEFFREY”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
UNIV VANDERBILT
35 patentsUS11820757B2Nov 21, 2023
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT5 citations84
US9056875B2Jun 16, 2015
Substituted pyrazolo[3′,4′:4,5]thieno[2,3-C]pyridazin-3-amine analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT18 citations84
US11299481B2Apr 12, 2022
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT5 citations83
US9868746B2Jan 16, 2018
Substituted 5-aminothieno[2,3-C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT9 citations83
US9637498B2May 2, 2017
Substituted thieno[2,3-C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT10 citations83
US9533982B2Jan 3, 2017
Substituted bicyclic heteroaryl carboxamide analogs as mGluR5 negative allosteric modulators
UNIV VANDERBILT10 citations83
US9493481B2Nov 15, 2016
Substituted 5-aminothieno[2,3—C]pyridazine-6-carboxamide analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT12 citations83
US8697888B2Apr 15, 2014
Substituted (1-(methylsulfonyl)azetidin-3-yl)(heterocycloalkyl)methanone analogs as antagonists of muscarinic acetylcholine M1 receptors
UNIV VANDERBILT9 citations83
US8034806B2Oct 11, 2011
Bicyclic mGluR5 positive allosteric modulators and methods of making and using same
UNIV VANDERBILT7 citations83
US10508105B2Dec 17, 2019
Indazole compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
UNIV VANDERBILT5 citations81
US10239887B2Mar 26, 2019
Positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT9 citations81
US9980945B2May 29, 2018
Benzoisoxazole-substituted compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
UNIV VANDERBILT8 citations81
US11352344B2Jun 7, 2022
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT4 citations73
US11225484B2Jan 18, 2022
Substituted octahydropyrrolo[3,4-b]pyrroles as antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT4 citations73
US11884676B2Jan 30, 2024
Substituted pyrimido[1,2-b]pyridazines as positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT4 citations72
US11414406B2Aug 16, 2022
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT3 citations72
US11325896B2May 10, 2022
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT2 citations72
US11149022B2Oct 19, 2021
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT4 citations72
US11008335B2May 18, 2021
Positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT2 citations72
US9586964B2Mar 7, 2017
Substituted 2-(4-heterocyclylbenzyl)isoindolin-1-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1
UNIV VANDERBILT4 citations72
US9012445B2Apr 21, 2015
Substituted 4-(1H-pyrazol-4-yl)benzyl analogues as positive allosteric modulators of mAChR M1 receptors
UNIV VANDERBILT4 citations72
US12319701B2Jun 3, 2025
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT2 citations71
US9382208B1Jul 5, 2016
Negative allosteric modulators of metabotropic glutamate receptor 2
UNIV VANDERBILT3 citations71
US9540371B2Jan 10, 2017
Substituted quinazolin-4(3H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, pyrido[3,2-d]pyrimidin-4(3H)-ones and pyrido[2,3-d]pyrimidin-4(3H)-ones as positive allosteric modulators of muscarinic acetycholine receptor M1
UNIV VANDERBILT2 citations70
US10927126B2Feb 23, 2021
Positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT2 citations69
US10526323B2Jan 7, 2020
Indazole and azaindazole substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
UNIV VANDERBILT2 citations69
US10227343B2Mar 12, 2019
Isoquiniline and napthalene-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
UNIV VANDERBILT3 citations68
US11376254B2Jul 5, 2022
Positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT1 citations62
US10934276B2Mar 2, 2021
Positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT1 citations62
US10221172B2Mar 5, 2019
Benzothiazole and benzisothiazole-substituted compounds as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
UNIV VANDERBILT1 citations62
US10189857B2Jan 29, 2019
Positive allosteric modulators of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT1 citations62
US9073935B2Jul 7, 2015
Substituted benzylspiroindolin-2-one analogs as positive allosteric modulators of the muscarinic acetylcholine receptor M1
UNIV VANDERBILT2 citations62
US9029563B2May 12, 2015
Substituted 1-benzylindolin-2-one analogs as positive allosteric modulators of muscarinic acetylcholine M1 receptors
UNIV VANDERBILT3 citations62
US7531541B2May 12, 2009
Partial mGluR5 antagonists for treatment of anxiety and CNS disorders
UNIV VANDERBILT2 citations62
US12577234B2Mar 17, 2026
Antagonists of the muscarinic acetylcholine receptor M4
UNIV VANDERBILT0 citations61
CONN P JEFFREY
15 patentsUS9180192B2Nov 10, 2015
mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY12 citations84
US8916584B2Dec 23, 2014
Benzisoxazoles and azabenzisoxazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY15 citations84
US8759377B2Jun 24, 2014
Substituted dioxopiperidines and dioxopyrrolidines as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY15 citations84
US8658650B2Feb 25, 2014
Substituted 1,1,3,1-tetraoxidobenzo[D][1,3,2]dithiazoles as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY15 citations84
US9192603B2Nov 24, 2015
Heterocyclic sulfone mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY12 citations83
US9163015B2Oct 20, 2015
Pyrazolopyridine, pyrarolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY12 citations83
US9108963B2Aug 18, 2015
Pyrazolopyridine, pyrazolopyrazine, pyrazolopyrimidine, pyrazolothiophene and pyrazolothiazole compounds as MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY12 citations83
US8912336B2Dec 16, 2014
Aryl and heteroaryl sulfones as mGluR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY12 citations83
US8796295B2Aug 5, 2014
Substituted benzamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same
CONN P JEFFREY4 citations82
US8779157B2Jul 15, 2014
MGLUR4 allosteric potentiators, compositions, and methods of treating neurological dysfunction
CONN P JEFFREY12 citations82
US8598345B2Dec 3, 2013
Substituted heteroarylamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same
CONN P JEFFREY6 citations82
US8501757B2Aug 6, 2013
Substituted phenylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same
CONN P JEFFREY5 citations82
US8569308B2Oct 29, 2013
Substituted heteroarylamine carboxamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same
CONN P JEFFREY4 citations72
US9085562B2Jul 21, 2015
6-alkyl-N-(pyridin-2-yl)-4-aryloxypicolinamide analogs as mGluR5 negative allosteric modulators and methods of making and using the same
CONN P JEFFREY4 citations71
US8592422B2Nov 26, 2013
Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors
CONN P JEFFREY5 citations71
Showing the top 50 of 92 patents by PatentIndex Score.