Inventor
FREEMAN JOHN J
US29 patents
⚠️ This page may combine multiple inventors who share the name “FREEMAN JOHN J”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
MANNKIND CORP
17 patentsUS8962836B2Feb 24, 2015
Formation of N-protected bis-3,6-(4-aminobutyl)-2,5-diketopiperazine through a cyclic alpha-N-protected amino ester
MANNKIND CORP9 citations92
US10870628B2Dec 22, 2020
Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic α-N-protected amino ester
MANNKIND CORP3 citations83
US10577331B2Mar 3, 2020
Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic alpha-N-protected amino ester intermediate
MANNKIND CORP5 citations83
US9944609B2Apr 17, 2018
Formation of N-protected bis-3,6-(4-aminobutyl)-2, 5-diketopiperazine through a cyclic alpha-N-protected amino ester
MANNKIND CORP6 citations83
US9187433B2Nov 17, 2015
Formation of N-protected 3,6-bis-(4-aminobutyl) -2, 5-diketopiperazine through a cyclic α-N-protected active amino ester intermediate
MANNKIND CORP8 citations83
US10640471B2May 5, 2020
Formation of N-protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine
MANNKIND CORP3 citations82
US10196366B2Feb 5, 2019
Formation of N-protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine
MANNKIND CORP3 citations82
US9416113B2Aug 16, 2016
Formation of N-protected bis-3,6-(4-aminoalkyl)-2,5,diketopiperazine
MANNKIND CORP3 citations82
US12049453B2Jul 30, 2024
Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic alpha-N-protected amino ester
MANNKIND CORP1 citations72
US11345668B2May 31, 2022
Formation of N-protected 3,6-bis-(4-aminobutyl)-2,5-diketopiperazine through a cyclic α-N-protected amino ester
MANNKIND CORP2 citations72
US11479535B2Oct 25, 2022
Methods for the synthesis of activated ethylfumarates and their use as intermediates
MANNKIND CORP2 citations71
US11440891B2Sep 13, 2022
Formation of N-protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine
MANNKIND CORP2 citations71
US10858325B2Dec 8, 2020
Methods for the synthesis of activated ethylfumarates and their use as intermediates
MANNKIND CORP3 citations71
US10071969B2Sep 11, 2018
Methods for the synthesis of activated ethylfumarates and their use as intermediates
MANNKIND CORP3 citations71
US12459903B2Nov 4, 2025
Formation of n-protected 3,6-bis-(4-aminoalkyl)-2,5,diketopiperazine
MANNKIND CORP0 citations60
US12202807B2Jan 21, 2025
Methods for the synthesis of activated ethylfumarates and their use as intermediates
MANNKIND CORP0 citations60
US9193691B2Nov 24, 2015
Methods for the synthesis of activated ethylfumarates and their use as intermediates
MANNKIND CORP3 citations59