Inventor
DESNICK ROBERT J
US28 patents
⚠️ This page may combine multiple inventors who share the name “DESNICK ROBERT J”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SINAI SCHOOL MEDICINE
14 patentsUS6583158B1Jun 24, 2003
Method for enhancing mutant enzyme activities in lysosomal storage disorders
SINAI SCHOOL MEDICINE168 citations99
US5580757ADec 3, 1996
Cloning and expression of biologically active α-galactosidase A as a fusion protein
SINAI SCHOOL MEDICINE145 citations98
US5356804AOct 18, 1994
Cloning and expression of biologically active human α-galactosidase A
SINAI SCHOOL MEDICINE137 citations97
US6541218B1Apr 1, 2003
Acid sphingomyelinase protein and methods of treating type B Niemann-Pick disease
SINAI SCHOOL MEDICINE52 citations96
US5686240ANov 11, 1997
Acid sphingomyelinase gene and diagnosis of Niemann-Pick disease
SINAI SCHOOL MEDICINE54 citations96
US8349319B2Jan 8, 2013
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
SINAI SCHOOL MEDICINE32 citations95
US5401650AMar 28, 1995
Cloning and expression of biologically active α-galactosidase A
SINAI SCHOOL MEDICINE77 citations95
US5491075AFeb 13, 1996
Cloning and expression of biologically active α-N-acetylgalactosaminidase
SINAI SCHOOL MEDICINE54 citations94
US7750050B2Jul 6, 2010
Chaperone-based therapy for Niemann-Pick disease
SINAI SCHOOL MEDICINE30 citations92
US5639607AJun 17, 1997
Method and kits for detecting a polymorphism in δ-aminolevulinate dehydratase gene which is associated with an altered susceptibility to lead poisoning
SINAI SCHOOL MEDICINE22 citations92
US5830850ANov 3, 1998
Methods for the treatment of bone resorption disorders, including osteoporosis
SINAI SCHOOL MEDICINE81 citations91
US5382524AJan 17, 1995
Cloning and expression of biologically active α-n-acetylgalactosaminidase
SINAI SCHOOL MEDICINE42 citations90
US6455037B1Sep 24, 2002
Cells expressing an αgala nucleic acid and methods of xenotransplantation
SINAI SCHOOL MEDICINE25 citations88
US5840578ANov 24, 1998
Methods for determining susceptibility to lead poisoning
SINAI SCHOOL MEDICINE13 citations73
ALNYLAM PHARMACEUTICALS INC
6 patentsUS9133461B2Sep 15, 2015
Compositions and methods for inhibiting expression of the ALAS1 gene
ALNYLAM PHARMACEUTICALS INC19 citations92
US9631193B2Apr 25, 2017
Compositions and methods for inhibiting expression of the ALAS1 gene
ALNYLAM PHARMACEUTICALS INC8 citations83
US10400239B2Sep 3, 2019
Compositions and methods for inhibiting expression of the ALAS1 gene
ALNYLAM PHARMACEUTICALS INC3 citations72
US10125364B2Nov 13, 2018
Compositions and methods for inhibiting expression of the ALAS1 gene
ALNYLAM PHARMACEUTICALS INC2 citations72
US10119143B2Nov 6, 2018
Compositions and methods for inhibiting expression of the ALAS1 gene
ALNYLAM PHARMACEUTICALS INC3 citations72
US11028392B2Jun 8, 2021
Compositions and methods for inhibiting expression of the ALAS1 gene
ALNYLAM PHARMACEUTICALS INC1 citations62
ICAHN SCHOOL MED MOUNT SINAI
6 patentsUS8658162B2Feb 25, 2014
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
ICAHN SCHOOL MED MOUNT SINAI10 citations91
US9655954B2May 23, 2017
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
ICAHN SCHOOL MED MOUNT SINAI8 citations83
US9114139B2Aug 25, 2015
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
ICAHN SCHOOL MED MOUNT SINAI6 citations83
US8709408B2Apr 29, 2014
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
ICAHN SCHOOL MED MOUNT SINAI9 citations83
US10188705B2Jan 29, 2019
Dose escalation enzyme replacement therapy for treating acid sphingomyelinase deficiency
ICAHN SCHOOL MED MOUNT SINAI2 citations72
US11279977B2Mar 22, 2022
Materials and methods for identifying spinal muscular atrophy carriers
ICAHN SCHOOL MED MOUNT SINAI0 citations54