Inventor
HERGENROTHER PAUL J
US57 patents
⚠️ This page may combine multiple inventors who share the name “HERGENROTHER PAUL J”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
UNIV ILLINOIS
40 patentsUS9102661B2Aug 11, 2015
Design, synthesis and evaluation of procaspase activating compounds as personalized anti-cancer drugs
UNIV ILLINOIS15 citations89
US8916705B2Dec 23, 2014
Procaspase-activating compounds and compositions
UNIV ILLINOIS12 citations84
US9663482B2May 30, 2017
Substituted piperazinyl acetohydrazide procaspase-activating compounds
UNIV ILLINOIS8 citations83
US9592229B2Mar 14, 2017
Potent anticancer activity via dual compound activation
UNIV ILLINOIS8 citations83
US9249116B2Feb 2, 2016
Enzyme-activating compounds and compositions
UNIV ILLINOIS10 citations83
US11129830B2Sep 28, 2021
PAC-1 combination therapy
UNIV ILLINOIS6 citations82
US9522901B2Dec 20, 2016
Compositions and methods including cell death inducers and procaspase activation
UNIV ILLINOIS6 citations82
US9382215B2Jul 5, 2016
Therapeutic methods and agents for treating myotonic dystrophy
UNIV ILLINOIS6 citations81
US8754084B2Jun 17, 2014
Therapeutic methods and agents for treating myotonic dystrophy
UNIV ILLINOIS10 citations81
US9643960B2May 9, 2017
Procaspase activating compounds
UNIV ILLINOIS7 citations80
US11510919B2Nov 29, 2022
Cancer therapy by degrading dual MEK signaling
UNIV ILLINOIS5 citations72
US10888560B2Jan 12, 2021
Procaspase 3 activation by combination therapy
UNIV ILLINOIS1 citations72
US10874666B2Dec 29, 2020
Procaspase combination therapy for glioblastoma
UNIV ILLINOIS1 citations71
US10350207B2Jul 16, 2019
PAC-1 combination therapy
UNIV ILLINOIS4 citations71
US9611266B2Apr 4, 2017
Compounds and anti-tumor NQO1 substrates
UNIV ILLINOIS3 citations71
US11046647B2Jun 29, 2021
Activators of the unfolded protein response
UNIV ILLINOIS2 citations68
US11274106B2Mar 15, 2022
Topoisomerase inhibitors with antibacterial and anticancer activity
UNIV ILLINOIS2 citations67
US10995097B2May 4, 2021
Small molecules active against gram-negative bacteria
UNIV ILLINOIS3 citations64
US12168006B2Dec 17, 2024
Cancer therapy by degrading dual MEK signaling
UNIV ILLINOIS1 citations62
US12433885B2Oct 7, 2025
Procaspase combination therapy for glioblastoma
UNIV ILLINOIS0 citations61
US12336992B2Jun 24, 2025
PAC-1 combination therapy
UNIV ILLINOIS0 citations61
US11844798B2Dec 19, 2023
Procaspase combination therapy for glioblastoma
UNIV ILLINOIS0 citations61
US11833147B2Dec 5, 2023
Procaspase 3 activation by combination therapy
UNIV ILLINOIS0 citations61
US11612598B2Mar 28, 2023
Compounds and methods for the treatment of cancer
UNIV ILLINOIS0 citations61
US10085978B2Oct 2, 2018
Procaspase combination therapy for glioblastoma
UNIV ILLINOIS1 citations61
US10085977B2Oct 2, 2018
Procaspase 3 activation by combination therapy
UNIV ILLINOIS1 citations61
US12180159B2Dec 31, 2024
Activators of the unfolded protein response
UNIV ILLINOIS0 citations58
US11584718B2Feb 21, 2023
Activators of the unfolded protein response
UNIV ILLINOIS0 citations58
US11858946B2Jan 2, 2024
Small molecules active against gram-negative bacteria
UNIV ILLINOIS0 citations54
US12090153B2Sep 17, 2024
Combination therapy for the treatment of uveal melanoma
UNIV ILLINOIS1 citations53
US11926877B2Mar 12, 2024
Saliva-based molecular testing for SARS-CoV-2
UNIV ILLINOIS0 citations53
US11530457B2Dec 20, 2022
Saliva-based molecular testing for SARS-CoV-2
UNIV ILLINOIS0 citations53
US10525056B2Jan 7, 2020
Procaspase-activating compounds and methods
UNIV ILLINOIS0 citations52
US10022371B2Jul 17, 2018
Procaspase-activating compounds and methods
UNIV ILLINOIS0 citations52
US9682060B2Jun 20, 2017
Small molecules that induce intrinsic pathway apoptosis
UNIV ILLINOIS0 citations52
US10285986B2May 14, 2019
Compounds and anti-tumor NQO1 substrates
UNIV ILLINOIS0 citations50
US10166229B2Jan 1, 2019
Compounds and methods for the treatment of cancer
UNIV ILLINOIS0 citations50
US9925180B2Mar 27, 2018
Compounds and anti-tumor NQO1 substrates
UNIV ILLINOIS0 citations50
US12180198B2Dec 31, 2024
Ribocil C antibiotics effective for Gram-negative pathogens
UNIV ILLINOIS0 citations49
US11691967B2Jul 4, 2023
Antibiotics effective for gram-negative pathogens
UNIV ILLINOIS0 citations49
HERGENROTHER PAUL J
4 patentsUS8592584B2Nov 26, 2013
Compositions and methods including cell death inducers and procaspase activation
HERGENROTHER PAUL J21 citations90
US9399035B2Jul 26, 2016
Procaspase 3 activation by combination therapy
HERGENROTHER PAUL J8 citations82
US9421202B2Aug 23, 2016
Procaspase combination therapy for glioblastoma
HERGENROTHER PAUL J9 citations80
US9233960B2Jan 12, 2016
Compounds and anti-tumor NQO1 substrates
HERGENROTHER PAUL J1 citations59
MASSACHUSETTS INST TECHNOLOGY
4 patentsUS9962383B2May 8, 2018
Compounds, compositions and methods of agelastatin alkaloids
MASSACHUSETTS INST TECHNOLOGY7 citations83
US9434736B2Sep 6, 2016
Compounds, compositions and methods of agelastatin alkaloids
MASSACHUSETTS INST TECHNOLOGY9 citations83
US10220099B2Mar 5, 2019
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]indole-1,4-diones for cancer treatment
MASSACHUSETTS INST TECHNOLOGY6 citations82
US9353150B2May 31, 2016
Substituted pyrazino[1′,2′:1 ,5]pyrrolo[2,3-b]-indole-1,4-diones for cancer treatment
MASSACHUSETTS INST TECHNOLOGY10 citations82
UNIV ALABAMA
1 patentUNIV TEXAS
1 patentShowing the top 50 of 57 patents by PatentIndex Score.