Inventor · disambiguated record
James Jefferson Smith
Also filed as: SMITH JAMES · SMITH JAMES J · SMITH JAMES JEFFERSON
73 granted patents·94 pending applications·2,930 citations·filing 1974–2025
99Inventor score
Top patents by PatentIndex Score
167 records- 0199US10041053B2Rationally-designed single-chain meganucleases with non-palindromic recognition sequencesPREC BIOSCIENCES INC·Filed 2016·Granted Aug 7, 2018·43 cites·11 claims
- 0299US9434931B2Rationally-designed single-chain meganucleases with non-palindromic recognition sequencesPREC BIOSCIENCES INC·Filed 2015·Granted Sep 6, 2016·63 cites·4 claims
- 0399US9340777B2Rationally-designed single-chain meganucleases with non-palindromic recognition sequencesPREC BIOSCIENCES INC·Filed 2015·Granted May 17, 2016·49 cites·8 claims
- 0499US8304222B1Rationally-designed meganucleases with altered sequence specificity and heterodimer formationSMITH JAMES JEFFERSON·Filed 2012·Granted Nov 6, 2012·80 cites·30 claims
- 0599US8163514B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Apr 24, 2012·185 cites·20 claims
- 0699US8148098B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Apr 3, 2012·88 cites·13 claims
- 0799US8143015B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Mar 27, 2012·90 cites·25 claims
- 0899US8143016B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Mar 27, 2012·89 cites·30 claims
- 0999US8133697B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Mar 13, 2012·181 cites·24 claims
- 1099US8129134B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Mar 6, 2012·180 cites·24 claims
- 1199US8124369B2Method of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Feb 28, 2012·173 cites·30 claims
- 1299US8119381B2Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinitySMITH JAMES JEFFERSON·Filed 2011·Granted Feb 21, 2012·182 cites·20 claims
- 1399US8119361B2Methods of cleaving DNA with rationally-designed meganucleasesSMITH JAMES JEFFERSON·Filed 2011·Granted Feb 21, 2012·108 cites·21 claims
- 1499US8021867B2Rationally-designed meganucleases with altered sequence specificity and DNA-binding affinityUNIV DUKE·Filed 2006·Granted Sep 20, 2011·304 cites·19 claims
- 1598US10851358B2Engineered meganucleases specific for recognition sequences in the hepatitis B virus genomePREC BIOSCIENCES INC·Filed 2020·Granted Dec 1, 2020·11 cites·13 claims
- 1698US9889161B2Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2017·Granted Feb 13, 2018·27 cites·4 claims
- 1798US9889160B2Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2017·Granted Feb 13, 2018·65 cites·9 claims
- 1898US8445251B2Rationally-designed single-chain meganucleases with non-palindromic recognition sequencesSMITH JAMES J·Filed 2010·Granted May 21, 2013·135 cites·1 claims
- 1997US10093900B2Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted Oct 9, 2018·15 cites·9 claims
- 2097US9993501B2Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted Jun 12, 2018·11 cites·13 claims
- 2197US9993502B1Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted Jun 12, 2018·16 cites·13 claims
- 2297US9969975B1Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted May 15, 2018·13 cites·9 claims
- 2397US9950010B1Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted Apr 24, 2018·14 cites·8 claims
- 2497US9950011B1Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted Apr 24, 2018·14 cites·8 claims
- 2596US4845402ACathode ray display tube having external magnetic shieldPHILIPS CORP·Filed 1987·Granted Jul 4, 1989·149 cites·14 claims
- 2695US9683257B2Recognition sequences for I-CreI-derived meganucleases and uses thereofPREC BIOSCIENCES INC·Filed 2014·Granted Jun 20, 2017·10 cites·10 claims
- 2795US3988889ACowling arrangement for a turbofan engineGEN ELECTRIC·Filed 1974·Granted Nov 2, 1976·267 cites·9 claims
- 2894US10822610B2Methods for producing a complex transgenic trait locusPIONEER HI BRED INT·Filed 2018·Granted Nov 3, 2020·4 cites·3 claims
- 2994US10287626B2Recognition sequences for I-CreI-derived meganucleases and uses thereofPREC BIOSCIENCES INC·Filed 2017·Granted May 14, 2019·5 cites·11 claims
- 3094US10093899B1Genetically-modified cells comprising a modified human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2018·Granted Oct 9, 2018·8 cites·9 claims
- 3193US11274285B2Engineered meganucleases specific for recognition sequences in the Hepatitis B virus genomePREC BIOSCIENCES INC·Filed 2020·Granted Mar 15, 2022·2 cites·18 claims
- 3293US10799535B2Engineered meganucleases with recognition sequences found in the human T cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2016·Granted Oct 13, 2020·5 cites·5 claims
- 3393US10662416B2Engineered meganucleases specific for recognition sequences in the hepatitis B virus genomePREC BIOSCIENCES INC·Filed 2017·Granted May 26, 2020·4 cites·9 claims
- 3493US10273524B2Recognition sequences for I-CreI-derived meganucleases and uses thereofPREC BIOSCIENCES INC·Filed 2017·Granted Apr 30, 2019·5 cites·11 claims
- 3593US8338157B2Rationally-designed meganuclease variants of lig-34 and I-crei for maize genome engineeringJANTZ DEREK·Filed 2010·Granted Dec 25, 2012·28 cites·3 claims
- 3692US11459576B2Methods for producing a complex transgenic trait locusPIONEER HI BRED INT·Filed 2020·Granted Oct 4, 2022·2 cites·3 claims
- 3791US11142750B2Optimized engineered meganucleases having specificity for a recognition sequence in the Hepatitis B virus genomePREC BIOSCIENCES INC·Filed 2019·Granted Oct 12, 2021·3 cites·6 claims
- 3891US11053484B2Genetically-modified T cells comprising a modified intron in the T cell receptor alpha genePREC BIOSCIENCES INC·Filed 2018·Granted Jul 6, 2021·5 cites·10 claims
- 3991US10603363B2Treatment of retinitis pigmentosa using engineered meganucleasesPREC BIOSCIENCES INC·Filed 2016·Granted Mar 31, 2020·3 cites·10 claims
- 4090US11680254B2Engineered meganucleases specific for recognition sequences in the PCSK9 genePREC BIOSCIENCES INC·Filed 2018·Granted Jun 20, 2023·3 cites·8 claims
- 4190US2024228994A9Rationally-designed meganucleases with altered sequence specificity and dna-binding affinityUNIV DUKE·Filed 2023·Application pending·0 cites
- 4289US12351839B2Rationally-designed single-chain meganucleases with non-palindromic recognition sequencesPREC BIOSCIENCES INC·Filed 2023·Granted Jul 8, 2025·0 cites·11 claims
- 4388US4561540AMicroscope drapeXOMED INC·Filed 1983·Granted Dec 31, 1985·58 cites·7 claims
- 4487US9822381B2Methods and products for producing engineered mammalian cell lines with amplified transgenesPREC BIOSCIENCES INC·Filed 2015·Granted Nov 21, 2017·2 cites·11 claims
- 4587US9604376B2Personal grooming assistantSKYWORLD INNOVATIONS LLC·Filed 2015·Granted Mar 28, 2017·17 cites·17 claims
- 4687US8377674B2Method for producing genetically-modified cells with rationally-designed meganucleases with altered sequence specificityUNIV DUKE·Filed 2012·Granted Feb 19, 2013·4 cites·25 claims
- 4787US2024401110A1Recognition sequences for i-crei-derived meganucleases and uses thereofPREC BIOSCIENCES INC·Filed 2024·Application pending·0 cites
- 4887US2024002796A1Genetically-modified cells comprising a modified human t cell receptor alpha constant region genePREC BIOSCIENCES INC·Filed 2023·Application pending·0 cites
- 4987US2025082735A1Precise deletion of chromosomal sequences in vivo and treatment of nucleotide repeat expansion disorders using engineered nucleasesPREC BIOSCIENCES INC·Filed 2024·Application pending·0 cites
- 5087US2024238387A1Treatment of retinitis pigmentosa using engineered meganucleasesPREC BIOSCIENCES INC·Filed 2023·Application pending·0 cites
Showing the top 50 of 167 patent records by PatentIndex Score.
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