Inventor · disambiguated record
Robert J. Lefkowitz
Also filed as: LEFKOWITZ ROBERT · LEFKOWITZ ROBERT J
19 granted patents·15 pending applications·422 citations·filing 1993–2023
95Inventor score
Top patents by PatentIndex Score
34 records- 0193US5482835AMethods of testing in yeast cells for agonists and antagonists of mammal G-protein coupled receptorsUNIV DUKE·Filed 1993·Granted Jan 9, 1996·99 cites·19 claims
- 0289US6436908B1Use of exogenous β-adrenergic receptor and β-adrenergic receptor kinase gene constructs to enhance myocardial functionUNIV DUKE·Filed 1999·Granted Aug 20, 2002·143 cites·15 claims
- 0389US5739029AVectors for expression of G protein coupled receptors in yeastUNIV DUKE·Filed 1995·Granted Apr 14, 1998·51 cites·12 claims
- 0487US6627602B2Preventing desensitization of receptorsUNIV DUKE·Filed 2002·Granted Sep 30, 2003·24 cites·16 claims
- 0583US6964984B2Preventing desensitization of receptorsUNIV DUKE·Filed 2003·Granted Nov 15, 2005·15 cites·2 claims
- 0682US6528271B1Inhibition of βarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesiaUNIV DUKE·Filed 1999·Granted Mar 4, 2003·32 cites·12 claims
- 0780US6855550B2Expression of G protein coupled receptors in yeastUNIV DUKE·Filed 2000·Granted Feb 15, 2005·4 cites·11 claims
- 0869US6168927B1Expression of G protein coupled receptors in yeastUNIV DUKE·Filed 1998·Granted Jan 2, 2001·12 cites·18 claims
- 0968US6605424B1Method of detecting inhibitors of agonist-specific desensitizationUNIV DUKE·Filed 2000·Granted Aug 12, 2003·6 cites·5 claims
- 1066US7060871B2Use of exogenous β-adrenergic receptor and β-adrenergic receptor kinase gene constructs to enhance myocardial functionUNIV DUKE·Filed 2002·Granted Jun 13, 2006·1 cites·2 claims
- 1160US7615610B2Modified trafficking patterns for arrestin and G-protein-coupled receptors via arrestin-ubiquitin chimeraUNIV DUKE·Filed 2004·Granted Nov 10, 2009·1 cites·9 claims
- 1260US2024101642A1System and method for homogenous gpcr phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulatorsUNIV DUKE·Filed 2023·Application pending·0 cites
- 1360US2004038313A1Inhibitors of agonist-specific desensitizationUNIV DUKE·Filed 2003·Application pending·0 cites
- 1459US7413876B2Expression of G protein coupled receptors in yeastDUKE UNIVERSITY OFFICE OF SCIE·Filed 2004·Granted Aug 19, 2008·0 cites·13 claims
- 1554US2006100159A1Preventing desensitization of receptorsUNIV DUKE·Filed 2005·Application pending·0 cites
- 1652US2022315574A1Beta-Arrestin-Modulating Compounds and Methods of Using SameUNIV DUKE·Filed 2020·Application pending·0 cites
- 1752US2022257583A1Compositions and Methods for the Treatment of Intracranial DiseasesUNIV DUKE·Filed 2020·Application pending·0 cites
- 1851US2011236907A1Radiolabled cyclopamine assay for the smoothened receptorCHEN WEI·Filed 2009·Application pending·0 cites
- 1951US2003215887A1Methods of testing for agonists and antagonists of cell surface receptorsUNIV DUKE·Filed 2003·Application pending·0 cites
- 2050US11866482B2System and method for homogenous GPCR phosphorylation and identification of beta-2 adrenergic receptor positive allosteric modulatorsUNIV DUKE·Filed 2019·Granted Jan 9, 2024·0 cites·6 claims
- 2150US2006029983A1Methods of screening compounds for GRK6 modulating activityOAKLEY ROBERT H·Filed 2005·Application pending·0 cites
- 2249US10682397B2Methods of treating fragile X syndrome and related disordersMASSACHUSETTS INST TECHNOLOGY·Filed 2016·Granted Jun 16, 2020·0 cites·9 claims
- 2349US5573908AAdrenergic receptor as a proto-oncogeneUNIV DUKE·Filed 1993·Granted Nov 12, 1996·13 cites·8 claims
- 2448US5981487AMethod of inhibiting smooth muscle cell proliferationUNIV DUKE·Filed 1997·Granted Nov 9, 1999·6 cites·18 claims
- 2548US2011071198A1Nicotinic acid receptor ligandsLEFKOWITZ ROBERT J·Filed 2009·Application pending·0 cites
- 2647US2003097671A1Inhibition of betaarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesiaFiled 2003·Application pending·0 cites
- 2747US2009263317A1Method of screening the activity of the smoothened receptor to identify theraputic modulation agents or diagnose diseaseCHEN WEI·Filed 2006·Application pending·0 cites
- 2846US2009023655A1Biased Ligands for Receptors Such as the PTH ReceptorLUTTRELL LOUIS·Filed 2008·Application pending·0 cites
- 2945US2010184107A1Protein traffickingLEFKOWITZ ROBERT J·Filed 2008·Application pending·0 cites
- 3041US6096705AInhibition of agonist-specific desensitization of β2 adrenergic receptorsUNIV DUKE·Filed 1993·Granted Aug 1, 2000·6 cites·8 claims
- 3141US2002198151A1Intracellular inhibitors of Gq protein signalingUNIV DUKE·Filed 2002·Application pending·0 cites
- 3240US6683057B1Method of inhibiting smooth muscle cell proliferationUNIV DUKE·Filed 1999·Granted Jan 27, 2004·5 cites·26 claims
- 3334US2011178015A1Methods of treatment using biased ligands for receptors such as the pth receptorLUTTRELL LOUIS·Filed 2010·Application pending·0 cites
- 3433US6610532B2Intracellular inhibitors of Gq protein signalingUNIV DUKE·Filed 1998·Granted Aug 26, 2003·4 cites·7 claims
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