Inventor
RYAN KENNETH M
US17 patents
⚠️ This page may combine multiple inventors who share the name “RYAN KENNETH M”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
MERCK & CO INC
16 patentsUS4269772AMay 26, 1981
Synthesis of thienamycin via trans-3-carboxymethylene-4-carboxy-5-methyl-Δ2 -isoxazoline
MERCK & CO INC29 citations92
US4287123ASep 1, 1981
Synthesis of thienamycin via (3SR, 4RS)-3-((RS)-1-acyloxyethyl)-2-oxo-4-azetidineacetate
MERCK & CO INC24 citations82
US4282148AAug 4, 1981
Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
MERCK & CO INC28 citations82
US4473502ASep 25, 1984
Synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
MERCK & CO INC9 citations73
US4467107AAug 21, 1984
1-Hydroxyethyl-2-amino pentanedioic acid derivatives
MERCK & CO INC6 citations73
US4414155ANov 8, 1983
Synthesis of thienamycin via esters of (3SR, 4RS)-3-[(SR)-1-hydroxyethyl]-β,2-dioxo-4-azetidinebutanoic acid
MERCK & CO INC10 citations73
US4349687ASep 14, 1982
Intermediate for synthesis of thienamycin via (3SR, 4RS)-3-[1 (SR)-hydroxyethyl]-2-oxo-4-azetidineacetic acid
MERCK & CO INC9 citations73
US4344885AAug 17, 1982
Intermediate for the preparation of thienamycin
MERCK & CO INC9 citations73
US4252722AFeb 24, 1981
Process for the preparation of 6-hydroxymethyl-2-(β-aminoethylthio)-1-carbadethiapen-2-em-3-carboxylic acid
MERCK & CO INC10 citations73
US4360684ANov 23, 1982
Process for the preparation of (2S)-tetrahydro-2α-methyl-6-oxo-4βα-carboxylic acid
MERCK & CO INC10 citations70
US5420353AMay 30, 1995
Regiospecific process to make cis-1-amino-2-alkanol from epoxide
MERCK & CO INC8 citations69
US5087703AFeb 11, 1992
Process for synthesis of FK-506 intermediates
MERCK & CO INC2 citations63
US4499278AFeb 12, 1985
Trans-3-carboxymethylene-4-carboxy-5-methyl-delta2-isoxazoline as intermediate
MERCK & CO INC5 citations62
US4454332AJun 12, 1984
Hydroxy amino dicarboxylic acids and esters
MERCK & CO INC3 citations62
US5489710AFeb 6, 1996
Regiospecific processes to make cis-1-amino-2-alkanol from diol
MERCK & CO INC1 citations51
US4375433AMar 1, 1983
Process for the preparation of 6-hydroxymethyl-2-(β-aminoethylthio)-1-carbadethiapen-2-em-3-carboxylic acid
MERCK & CO INC0 citations51