Inventor
GELFAND DAVID H
US52 patents
⚠️ This page may combine multiple inventors who share the name “GELFAND DAVID H”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
HOFFMANN LA ROCHE
17 patentsUS5641864AJun 24, 1997
Kits for high temperature reverse transcription of RNA
HOFFMANN LA ROCHE139 citations99
US5624833AApr 29, 1997
Purified thermostable nucleic acid polymerase enzyme from Thermotoga maritima
HOFFMANN LA ROCHE119 citations99
US5618711AApr 8, 1997
Recombinant expression vectors and purification methods for Thermus thermophilus DNA polymerase
HOFFMANN LA ROCHE301 citations99
US5618703AApr 8, 1997
Unconventional nucleotide substitution in temperature selective RT-PCR
HOFFMANN LA ROCHE122 citations99
US5487972AJan 30, 1996
Nucleic acid detection by the 5'-3'exonuclease activity of polymerases acting on adjacently hybridized oligonucleotides
HOFFMANN LA ROCHE855 citations99
US5407800AApr 18, 1995
Reverse transcription with Thermus thermophilus polymerase
HOFFMANN LA ROCHE167 citations99
US5374553ADec 20, 1994
DNA encoding a thermostable nucleic acid polymerase enzyme from thermotoga maritima
HOFFMANN LA ROCHE306 citations99
US5310652AMay 10, 1994
Reverse transcription with thermostable DNA polymerase-high temperature reverse transcription
HOFFMANN LA ROCHE386 citations99
US5210015AMay 11, 1993
Homogeneous assay system using the nuclease activity of a nucleic acid polymerase
HOFFMANN LA ROCHE2,135 citations99
US5466591ANov 14, 1995
5' to 3' exonuclease mutations of thermostable DNA polymerases
HOFFMANN LA ROCHE229 citations98
US5455170AOct 3, 1995
Mutated thermostable nucleic acid polymerase enzyme from Thermus species Z05
HOFFMANN LA ROCHE136 citations98
US5418149AMay 23, 1995
Reduction of non-specific amplification glycosylase using DUTP and DNA uracil
HOFFMANN LA ROCHE399 citations98
US5561058AOct 1, 1996
Methods for coupled high temperatures reverse transcription and polymerase chain reactions
HOFFMANN LA ROCHE170 citations97
US5420029AMay 30, 1995
Mutated thermostable nucleic acid polymerase enzyme from thermotoga maritima
HOFFMANN LA ROCHE95 citations97
US5491086AFeb 13, 1996
Purified thermostable nucleic acid polymerase and DNA coding sequences from pyrodictium species
HOFFMANN LA ROCHE72 citations96
US5352600AOct 4, 1994
Purified thermostable enzyme
HOFFMANN LA ROCHE97 citations96
US5405774AApr 11, 1995
DNA encoding a mutated thermostable nucleic acid polymerase enzyme from thermus species sps17
HOFFMANN LA ROCHE98 citations95
ROCHE MOLECULAR SYSTEMS INC
14 patentsUS7141377B2Nov 28, 2006
Process for discrimination of nucleic acid sequence variants
ROCHE MOLECULAR SYSTEMS INC81 citations99
US6197563B1Mar 6, 2001
Kits for amplifying and detecting nucleic acid sequences
ROCHE MOLECULAR SYSTEMS INC141 citations99
US6127155AOct 3, 2000
Stabilized thermostable nucleic acid polymerase compositions containing non-ionic polymeric detergents
ROCHE MOLECULAR SYSTEMS INC182 citations99
US6040166AMar 21, 2000
Kits for amplifying and detecting nucleic acid sequences, including a probe
ROCHE MOLECULAR SYSTEMS INC178 citations99
US5804375ASep 8, 1998
Reaction mixtures for detection of target nucleic acids
ROCHE MOLECULAR SYSTEMS INC585 citations99
US5789224AAug 4, 1998
Recombinant expression vectors and purification methods for thermus thermophilus DNA polymerase
ROCHE MOLECULAR SYSTEMS INC139 citations99
US7445900B2Nov 4, 2008
Homogeneous assay system
ROCHE MOLECULAR SYSTEMS INC56 citations98
US5674738AOct 7, 1997
DNA encoding thermostable nucleic acid polymerase enzyme from thermus species Z05
ROCHE MOLECULAR SYSTEMS INC181 citations98
US5795762AAug 18, 1998
5' to 3' exonuclease mutations of thermostable DNA polymerases
ROCHE MOLECULAR SYSTEMS INC96 citations97
US6514736B1Feb 4, 2003
Kits for amplifying and detecting nucleic acid sequences
ROCHE MOLECULAR SYSTEMS INC71 citations96
US5693517ADec 2, 1997
Reagents and methods for coupled high temperature reverse transcription and polymerase chain reactions
ROCHE MOLECULAR SYSTEMS INC135 citations96
US5968799AOct 19, 1999
Purified thermostable nucleic acid polymerase enzyme from thermosipho africanus
ROCHE MOLECULAR SYSTEMS INC60 citations92
US7745125B2Jun 29, 2010
2′-terminator related pyrophosphorolysis activated polymerization
ROCHE MOLECULAR SYSTEMS INC24 citations90
US7148049B2Dec 12, 2006
Thermostable or thermoactive DNA polymerase molecules with attenuated 3′-5′ exonuclease activity
ROCHE MOLECULAR SYSTEMS INC13 citations82
CETUS CORP
14 patentsUS5079352AJan 7, 1992
Purified thermostable enzyme
CETUS CORP555 citations99
US4965188AOct 23, 1990
Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
CETUS CORP3,972 citations99
US4889818ADec 26, 1989
Purified thermostable enzyme
CETUS CORP1,184 citations99
US5075216ADec 24, 1991
Methods for dna sequencing with thermus aquaticus dna polymerase
CETUS CORP260 citations96
US4784949ANov 15, 1988
Universal dominant selectable marker cassette
CETUS CORP53 citations96
US4711845ADec 8, 1987
Portable temperature-sensitive control cassette
CETUS CORP80 citations96
US5116750AMay 26, 1992
Selectable fusion protein having aminoglycoside phosphotransferase activity
CETUS CORP23 citations92
US4666848AMay 19, 1987
Polypeptide expression using a portable temperature sensitive control cassette with a positive retroregulatory element
CETUS CORP44 citations92
US4830962AMay 16, 1989
Recombinant diphtheria toxin fragments
CETUS CORP37 citations91
US5268274ADec 7, 1993
Methods and nucleic acid sequences for the expression of the cellulose synthase operon
CETUS CORP30 citations89
US4870013ASep 26, 1989
SV40 early and RSV promoters useful in saccharomyces expression
CETUS CORP12 citations74
US4631257ADec 23, 1986
Stable high copy number plasmids
CETUS CORP7 citations74
US4966840AOct 30, 1990
Stable high copy number plasmids
CETUS CORP0 citations52
US5045463ASep 3, 1991
DNA expression vector and use thereof
CETUS CORP0 citations50
BAUER KEITH A
2 patentsHOFFMAN LAROCHE INC
1 patentROCHE MOLECULAR SYSTEMS
1 patentWEYERHAEUSER
1 patentShowing the top 50 of 52 patents by PatentIndex Score.