Inventor · disambiguated record
Brian Safina
Also filed as: SAFINA BRIAN · SAFINA BRIAN S · SAFINA BRIAN SALVATORE
47 granted patents·46 pending applications·341 citations·filing 2006–2025
98Inventor score
Files withGENENTECH INC37BOLT BIOTHERAPEUTICS INC27ARRAY BIOPHARMA INC15CASTANEDO GEORGETTE4MITCHELL IAN S3
Top patents by PatentIndex Score
93 records- 0197US8933236B2N-substituted benzamides and methods of use thereofGENENTECH INC·Filed 2013·Granted Jan 13, 2015·50 cites·32 claims
- 0297US8063050B2Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitorsMITCHELL IAN S·Filed 2007·Granted Nov 22, 2011·63 cites·103 claims
- 0395US8952169B2N-substituted benzamides and methods of use thereofGENENTECH INC·Filed 2013·Granted Feb 10, 2015·25 cites·43 claims
- 0495US8003651B2Pyrimidyl cyclopentanes as AKT protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2007·Granted Aug 23, 2011·35 cites·76 claims
- 0594US8853199B2Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitorsMITCHELL IAN S·Filed 2011·Granted Oct 7, 2014·20 cites·33 claims
- 0692US9694002B2Substituted benzamides and methods of use thereofGENENTECH INC·Filed 2016·Granted Jul 4, 2017·11 cites·10 claims
- 0792US9546164B2Substituted benzamides and methods of use thereofGENENTECH INC·Filed 2015·Granted Jan 17, 2017·13 cites·38 claims
- 0891US9771376B2N-substituted benzamides and methods of use thereofGENENTECH INC·Filed 2016·Granted Sep 26, 2017·7 cites·19 claims
- 0990US11654199B2Thienoazepine immunoconjugates, and uses thereofBOLT BIOTHERAPEUTICS INC·Filed 2020·Granted May 23, 2023·2 cites·26 claims
- 1090US9359340B2Hydroxylated and methoxylated pyrimidyl cyclopentanes as Akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2014·Granted Jun 7, 2016·9 cites·101 claims
- 1189US8377937B2Pyrimidyl cyclopentanes as AKT protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2008·Granted Feb 19, 2013·15 cites·37 claims
- 1288US8846681B2Pyrimidyl cyclopentanes as AKT protein kinase inhibitorsMITCHELL IAN S·Filed 2011·Granted Sep 30, 2014·11 cites·91 claims
- 1387US10005724B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2015·Granted Jun 26, 2018·6 cites·11 claims
- 1485US8394796B2Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of useCASTANEDO GEORGETTE·Filed 2012·Granted Mar 12, 2013·8 cites·20 claims
- 1583US10533058B2Peptidomimetic compounds and antibody-drug conjugates thereofGENENTECH INC·Filed 2014·Granted Jan 14, 2020·2 cites·7 claims
- 1683US9550775B2Substituted triazolopyridines and methods of use thereofGENENTECH INC·Filed 2014·Granted Jan 24, 2017·7 cites·26 claims
- 1783US8563540B2Pyrido[3,2-d]pyrimidine PI3K delta inhibitor compounds and methods of useGENENTECH INC·Filed 2013·Granted Oct 22, 2013·6 cites·9 claims
- 1883US8173650B2Bicyclic pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of useCASTANEDO GEORGETTE·Filed 2010·Granted May 8, 2012·7 cites·21 claims
- 1982US8618097B2Pyrimidyl cyclopentanes as AKT protein kinase inhibitorsBENCSIK JOSEF·Filed 2008·Granted Dec 31, 2013·7 cites·48 claims
- 2081US10124069B2Peptidomimetic compounds and antibody-drug conjugates thereofGENENTECH INC·Filed 2016·Granted Nov 13, 2018·3 cites·26 claims
- 2181US10125098B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2018·Granted Nov 13, 2018·2 cites·12 claims
- 2281US8158625B2Bicyclic indole-pyrimidine PI3K inhibitor compounds selective for P110 delta, and methods of useCASTANEDO GEORGETTE·Filed 2010·Granted Apr 17, 2012·6 cites·7 claims
- 2381US2025042917A1Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2024·Application pending·0 cites
- 2478US8653089B2Heterocyclic compounds and methods of useHEALD ROBERT·Filed 2012·Granted Feb 18, 2014·5 cites·3 claims
- 2578US8440651B2Pyrido[3,2-d]pyrimidine PI3K delta inhibitor compounds and methods of useCASTANEDO GEORGETTE·Filed 2011·Granted May 14, 2013·4 cites·8 claims
- 2677US8853216B2Hydroxylated pyrimidyl cyclopentane as AKT protein kinase inhibitorBENCSIK JOSEF·Filed 2009·Granted Oct 7, 2014·3 cites·5 claims
- 2777US2022226326A1Hydroxylated and methoxylated pyrimidyl cyclopentanes as akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2021·Application pending·0 cites
- 2877US2025152588A1Hydroxylated and methoxylated pyrimidyl cyclopentanes as akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2025·Application pending·0 cites
- 2976US11130726B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2019·Granted Sep 28, 2021·0 cites·20 claims
- 3076US10787446B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2018·Granted Sep 29, 2020·1 cites·26 claims
- 3176US10526285B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2018·Granted Jan 7, 2020·1 cites·17 claims
- 3275US10947251B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2019·Granted Mar 16, 2021·1 cites·20 claims
- 3375US8846683B2Pyrimidyl cyclopentanes as Akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2013·Granted Sep 30, 2014·1 cites·35 claims
- 3475US8293736B2Purine compounds selective for PI3K P110 delta, and methods of useLI JUN·Filed 2011·Granted Oct 23, 2012·3 cites·15 claims
- 3575US2022055977A1Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2021·Application pending·0 cites
- 3673US9409886B2Pyrimidyl cyclopentanes as AKT protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2013·Granted Aug 9, 2016·2 cites·50 claims
- 3771US8835434B2Hydroxylated pyrimidyl cyclopentanes as akt protein kinase inhibitorsBENCSIK JOSEF R·Filed 2009·Granted Sep 16, 2014·2 cites·2 claims
- 3871US2020345735A1Hydroxylated and methoxylated pyrimidyl cyclopentanes as akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2020·Application pending·0 cites
- 3970US12465653B2Thienoazepine immunoconjugates, and uses thereofBOLT BIOTHERAPEUTICS INC·Filed 2023·Granted Nov 11, 2025·0 cites·30 claims
- 4070US11149002B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2019·Granted Oct 19, 2021·0 cites·13 claims
- 4170US10071957B2N-substituted benzamides and methods of use thereofGENENTECH INC·Filed 2013·Granted Sep 11, 2018·1 cites·2 claims
- 4269US9999681B2Peptidomimetic compounds and antibody-drug conjugates thereofGENENTECH INC·Filed 2016·Granted Jun 19, 2018·1 cites·30 claims
- 4369US2021093618A1Substituted benzamides and methods of use thereofGENENTECH INC·Filed 2019·Application pending·0 cites
- 4467US12139496B2Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2021·Granted Nov 12, 2024·0 cites·16 claims
- 4567US2020108054A1Substituted benzamides and methods of use thereofGENENTECH INC·Filed 2019·Application pending·0 cites
- 4667US2018230079A1Therapeutic compounds and methods of use thereofGENENTECH INC·Filed 2018·Application pending·0 cites
- 4764US2015224071A1N-substituted benzamides and methods of use thereofGENENTECH INC·Filed 2014·Application pending·0 cites
- 4864US2014315887A1Pyrimidyl cyclopentanes as akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2014·Application pending·0 cites
- 4964US2018169099A1Hydroxylated and methoxylated pyrimidyl cyclopentanes as akt protein kinase inhibitorsARRAY BIOPHARMA INC·Filed 2017·Application pending·0 cites
- 5063US11692043B2Peptidomimetic compounds and antibody-drug conjugates thereofGENENTECH INC·Filed 2019·Granted Jul 4, 2023·0 cites·6 claims
Showing the top 50 of 93 patent records by PatentIndex Score.
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