Inventor
MONROE KYLE D
US13 patents
Patents
13 patentsUS10980801B2Apr 20, 2021
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
SRX CARDIO LLC6 citations83
US10865185B2Dec 15, 2020
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity
SRX CARDIO LLC5 citations83
US10568882B2Feb 25, 2020
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
SRX CARDIO LLC6 citations83
US10688114B2Jun 23, 2020
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity
SRX CARDIO LLC5 citations82
US10307433B2Jun 4, 2019
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity
SRX CARDIO LLC5 citations82
US10034892B2Jul 31, 2018
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity
SRX CARDIO LLC5 citations82
US10287317B2May 14, 2019
Proprotein convertase subtilisin kexin type 9 (PCSK9) allosteric binding ligands to modulate serum low density lipoprotein (LDL) levels
SRX CARDIO LLC12 citations80
US10821106B2Nov 3, 2020
Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity
SRX CARDIO LLC4 citations72
US11944619B2Apr 2, 2024
Phenylalanine small organic compounds to directly modulate PCSK9 protein activity
SRX CARDIO LLC0 citations61
US11945782B2Apr 2, 2024
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity
SRX CARDIO LLC0 citations61
US11925637B2Mar 12, 2024
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use
SRX CARDIO LLC0 citations61
US11771710B2Oct 3, 2023
Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands
SRX CARDIO LLC0 citations61
US11026957B2Jun 8, 2021
Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands
SRX CARDIO LLC0 citations61