Inventor
MORTENSEN DEBORAH
US16 patents
⚠️ This page may combine multiple inventors who share the name “MORTENSEN DEBORAH”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SIGNAL PHARM LLC
12 patentsUS9771371B2Sep 26, 2017
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
SIGNAL PHARM LLC4 citations83
US8907087B2Dec 9, 2014
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
SIGNAL PHARM LLC4 citations83
US9556126B2Jan 31, 2017
Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith
SIGNAL PHARM LLC10 citations82
US9156798B2Oct 13, 2015
Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith
SIGNAL PHARM LLC5 citations82
US9155736B2Oct 13, 2015
Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for TOR kinase inhibitory activity
SIGNAL PHARM LLC16 citations82
US9079900B2Jul 14, 2015
Methods of synthesis and purification of heteroaryl compounds
SIGNAL PHARM LLC5 citations82
US10167290B2Jan 1, 2019
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
SIGNAL PHARM LLC1 citations72
US9783505B2Oct 10, 2017
Substituted diaminopyrimidyl compounds, compositions thereof, and methods of treatment therewith
SIGNAL PHARM LLC2 citations71
US11292796B2Apr 5, 2022
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
SIGNAL PHARM LLC0 citations62
US10683298B2Jun 16, 2020
Substituted pyrazino[2,3-b]pyrazines as mTOR kinase inhibitors
SIGNAL PHARM LLC0 citations51
US9193692B2Nov 24, 2015
Halogen substituted pyrazines as intermediates of mTOR kinase inhibitors
SIGNAL PHARM LLC0 citations51
US9557338B2Jan 31, 2017
Inhibition of phosphorylation of PRAS40, GSK3-beta or P70S6K1 as a marker for tor kinase inhibitory activity
SIGNAL PHARM LLC1 citations50
PERRIN-NINKOVIC SOPHIE
3 patentsUS8492381B2Jul 23, 2013
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
PERRIN-NINKOVIC SOPHIE44 citations95
US8110578B2Feb 7, 2012
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitors for oncology indications and diseases associated with the mTOR/PI3K/Akt pathway
PERRIN-NINKOVIC SOPHIE67 citations95
US8507492B2Aug 13, 2013
Pyrazino[2,3-b]pyrazine mTOR kinase inhibitor for oncology indications and diseases associated with the mTOR/PI3K/AKT pathway
PERRIN-NINKOVIC SOPHIE22 citations90