Inventor

MALAMAS MICHAEL S

US58 patents

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MALAMAS MICHAEL S

AMERICAN HOME PROD

Aryl-oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Aryl-N-hydroxyureas as inhibitors of 5-lipoxygenase and anto-arteriosclerotic agents

Aralkyl-1,2,4-oxadiazolidine-3,5-diones as antihyperglycemic agents

2-(3,5-di-tert-butyl-4-hydroxy-phenyl)-oxazoles as anti-atherosclerotic agents

Spiro-isoquinoline-pyrrolidines and analogs thereof useful as aldose reductase inhibitors

Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia

Biphenyl sulfonyl aryl carboxylic acids useful in the treatment of insulin resistance and hyperglycemia

New azolidinediones and thiadiazolidinediones as antihyperglycemic agents

Azolidinediones as antihyperglycemic agents

Naphthalenylsulfonylimidazolidinediones and their thioxo analogs useful as aldose reductase inhibitors

Di-oxadiazolidine derivatives as antihyperglycemic agents

Phenoxy acetic acids as aldose reductase inhibitors and antihyperglycemic agents

Aryl-n-hydroxyureas as inhbitors of 5-lipoxygenase and anti-arteriosclerotic agents

N-hydroxyureas as 5-lipoxygenase inhibitors and inhibitors of oxidative modification of low density lipoprotein

N-hydroxyureas as 5-lipoxygenase inhibitors and inhibitors of oxidative modification of low density lipoprotein

Naphthalenylmethyl cycloalkenone acetic acids and analogs thereof useful as aldose reductase inhibitors

Spiro-lactams and analogs thereof useful as aldose reductase inhibitors

Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Biphenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Substituted 1,3-benzodioxoles

Azolidinediones as antihypergylcemic agents

Aralkyl-N-hydroxyureas as inhibitors of 5-lipoxygenase and oxidation of low density lipoprotein

Isoquinoline-1,3-dione acetyl carbamates useful as aldose reductase inhibitors

Process and intermediates for the preparation of spiro(isoquinoline-4(1H), 3&#39;-pyrrolidine)-1,2&#39;, 3,5&#39;(2H)-tetrones which are useful as aldose reductase inhibitors

Spiro-pyridazines and analogs thereof useful as aldose reductase inhibitors

Alkylidene analogs of 1&#39;-aminospiro[isoquinoline-4(1H),3&#39;-pyrrolidine]-1,2&#39;,3,5&#39;(2H)-tetrones useful as aldose reductase inhibitors

N&#39;-alkyl-spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors

Isoquinoline acetic acids and acetyl carbamates useful as aldose reductase inhibitors

N-[[6-methoxy-5-(trifluoromethyl)-1-naphthalenyl]-thioxomethyl]-N-methylglycine S-oxide and the amide thereof

Naphthalenylmethyl cycloalkenone acetic acids and analogs thereof useful as aldose reductase inhibitors

Naphthalenylmethyl thiophenones as antihyperglycemic agents

Alkylidene analogs of 1&#39;-amino-2-[(benzothiazolyl)-methyl]spiro [isoquinoline-4(1H),3&#39;-pyrrolidine]-1,2&#39;,3,5&#39;(2H)-tetrones useful as aldose reductase inhibitors

1&#39;-amino-2[(benzothiazolyl)methyl]spiro-[isoquinoline-4(1H),3&#39;-pyrrolidine]-1,2&#39;3,5&#39;(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors

Process and intermediates for the preparation of spiro[isoquinoline-4(1H),3-pyrrolidine]1,2,3,5 (2H)-tetrones which are useful as aldose reductase inhibitors

WYETH CORP

Phenyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Substituted benzoxazoles as estrogenic agents

Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia

Substituted benzoxazoles as estrogenic agents

Cyclic amine phenyl beta-3 adrenergic receptor agonists

Naphthyl benzoxazoles and benzisoxazoles as estrogenic agents

Amino-5,5-diphenylimidazolone derivatives for the inhibition of β-secretase

Substituted benzoxazoles as estrogenic agents

Penyl oxo-acetic acids useful in the treatment of insulin resistance and hyperglycemia

Substituted imidazo[1,5-a]quinoxalines useful as inhibitors of phosphodiesterase 10 for the treatment of neurological and other disorders

Phenyl benzisoxazoles as estrogenic agents

Oxazole-aryl-carboxylic acids useful in the treatment of insulin resistance and hyperglycemia

(unassigned)

Amino-thiazolidinediones useful in the treatment of insulin resistance and hyperglycemia

Benzyl and naphthalenylmethyl thiophenones and cyclopentenones as antihyperglycemic agents

Process and intermediates for the preparation of spiro(isoquinoline-4(1H), 3'-pyrrolidine)-1,2', 3,5'(2H)-tetrones which are useful as aldose reductase inhibitors

Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors

N'-alkyl-spiro-isoquinoline-pyrrolidine tetrones and analogs thereof useful as aldose reductase inhibitors

Alkylidene analogs of 1'-amino-2-[(benzothiazolyl)-methyl]spiro [isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors

1'-amino-2[(benzothiazolyl)methyl]spiro-[isoquinoline-4(1H),3'-pyrrolidine]-1,2'3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors