Inventor
GRUBER HARRY E
US47 patents
⚠️ This page may combine multiple inventors who share the name “GRUBER HARRY E”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
CHIRON CORP
7 patentsUS5997859ADec 7, 1999
Method for treating a metastatic carcinoma using a conditionally lethal gene
CHIRON CORP46 citations96
US6133029AOct 17, 2000
Replication defective viral vectors for infecting human cells
CHIRON CORP21 citations92
US5856185AJan 5, 1999
Method for making reflection defective retroviral vectors for infecting human cells
CHIRON CORP32 citations90
US6241982B1Jun 5, 2001
Method for treating brain cancer with a conditionally lethal gene
CHIRON CORP12 citations74
US6410326B1Jun 25, 2002
Method for inhibiting human tumor cells
CHIRON CORP9 citations71
US6569679B1May 27, 2003
Producer cell that generates adenoviral vectors encoding a cytokine and a conditionally lethal gene
CHIRON CORP4 citations63
US6531307B1Mar 11, 2003
Adenoviral vectors encoding a cytokine and a conditionally lethal gene
CHIRON CORP3 citations63
GENSIA PHARMA
7 patentsUS5658889AAug 19, 1997
Method and compounds for aica riboside delivery and for lowering blood glucose
GENSIA PHARMA109 citations96
US5236908AAug 17, 1993
Methods of treating injury to the central nervous system
GENSIA PHARMA98 citations94
US5817640AOct 6, 1998
Methods of preventing tissue damage associated with decreased blood flow by administration of AICA riboside compounds
GENSIA PHARMA23 citations91
US5187162AFeb 16, 1993
Methods of treating neurodegenerative conditions
GENSIA PHARMA60 citations91
US5082829AJan 21, 1992
AICA riboside prodrugs
GENSIA PHARMA33 citations88
US5132291AJul 21, 1992
Antivirals and methods for increasing the antiviral activity of azt
GENSIA PHARMA19 citations82
US5200525AApr 6, 1993
Anti-seizure compounds
GENSIA PHARMA8 citations73
(unassigned)
6 patentsUS5851529ADec 22, 1998
Recombinant retroviruses
85 citations97
US5888502AMar 30, 1999
Recombinant retroviruses
57 citations96
US5691177ANov 25, 1997
Recombinant retroviruses expressing a protein that converts a pro-drug into a cytotoxic agent
62 citations96
US5830458ANov 3, 1998
Method for destroying a diseased human cell
19 citations92
US6603955B2Aug 5, 2003
Mission certification quiz for fundraising campaign
28 citations90
US6495349B1Dec 17, 2002
Chimeric gene constructs
1 citations62
UNIV CALIFORNIA
6 patentsUS4912092AMar 27, 1990
Methods for increasing extracellular adenosine and for stabilizing mast cells
UNIV CALIFORNIA74 citations96
US5118601AJun 2, 1992
Method of screening purine nucleoside compounds or analogs for the ability to enhance the cellular synthesis and release of adenosine
UNIV CALIFORNIA30 citations93
US5030623AJul 9, 1991
Methods for increasing extracellular adenosine and for stabilizing mast cells
UNIV CALIFORNIA22 citations93
US5008251AApr 16, 1991
Method of treating autism
UNIV CALIFORNIA24 citations93
US5747243AMay 5, 1998
Retrovirus detection method
UNIV CALIFORNIA5 citations73
US5503974AApr 2, 1996
Retrovirus detection
UNIV CALIFORNIA14 citations73
TOCAGEN INC
6 patentsUS10035983B2Jul 31, 2018
Gene therapy vectors and cytosine deaminases
TOCAGEN INC3 citations72
US9732326B2Aug 15, 2017
Recombinant vectors
TOCAGEN INC3 citations72
US9889133B2Feb 13, 2018
Formulations of 5-fluorocytosine and uses thereof
TOCAGEN INC1 citations61
US10449194B2Oct 22, 2019
Formulations of 5-fluorocytosine and uses thereof
TOCAGEN INC0 citations51
US10407666B2Sep 10, 2019
Recombinant vectors
TOCAGEN INC0 citations51
US9642921B2May 9, 2017
Cancer combination therapy and recombinant vectors
TOCAGEN INC1 citations47
GRUBER HARRY E
4 patentsUS9320738B2Apr 26, 2016
Formulations of 5-fluorocytosine and uses thereof
GRUBER HARRY E5 citations83
US8829173B2Sep 9, 2014
Recombinant vectors
GRUBER HARRY E8 citations83
US8722867B2May 13, 2014
Gene therapy vectors and cytosine deaminases
GRUBER HARRY E7 citations83
US9669049B2Jun 6, 2017
Compositions comprising gamma retrovirus vectors and methods of treating proliferative disorders
GRUBER HARRY E6 citations66
DENOVO BIOPHARMA LLC
3 patentsUS11065311B2Jul 20, 2021
Retroviral vector with mini-promoter cassette
DENOVO BIOPHARMA LLC2 citations71
US11230719B2Jan 25, 2022
Retroviral vector having immune-stimulating activity
DENOVO BIOPHARMA LLC2 citations69
US11191764B2Dec 7, 2021
Formulations of 5-fluorocytosine and uses thereof
DENOVO BIOPHARMA LLC0 citations61