Inventor
VARGEESE CHANDRA
US57 patents
⚠️ This page may combine multiple inventors who share the name “VARGEESE CHANDRA”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.
SIRNA THERAPEUTICS INC
22 patentsUS10000754B2Jun 19, 2018
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC35 citations98
US9771588B2Sep 26, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC44 citations98
US9732344B2Aug 15, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC43 citations98
US9657294B2May 23, 2017
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC36 citations98
US9181551B2Nov 10, 2015
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC102 citations98
US7893302B2Feb 22, 2011
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
SIRNA THERAPEUTICS INC152 citations98
US7491805B2Feb 17, 2009
Conjugates and compositions for cellular delivery
SIRNA THERAPEUTICS INC273 citations98
US7404969B2Jul 29, 2008
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
SIRNA THERAPEUTICS INC363 citations98
US7205399B1Apr 17, 2007
Methods and reagents for oligonucleotide synthesis
SIRNA THERAPEUTICS INC67 citations98
US7964578B2Jun 21, 2011
Conjugates and compositions for cellular delivery
SIRNA THERAPEUTICS INC66 citations97
US7691405B2Apr 6, 2010
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
SIRNA THERAPEUTICS INC51 citations97
US7514099B2Apr 7, 2009
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
SIRNA THERAPEUTICS INC67 citations97
US6995259B1Feb 7, 2006
Method for the chemical synthesis of oligonucleotides
SIRNA THERAPEUTICS INC103 citations97
US6989442B2Jan 24, 2006
Deprotection and purification of oligonucleotides and their derivatives
SIRNA THERAPEUTICS INC43 citations93
US7777023B2Aug 17, 2010
Method for the chemical synthesis of oligonucleotides
SIRNA THERAPEUTICS INC23 citations92
US7641915B2Jan 5, 2010
Lipid nanoparticle based compositions and methods for the delivery of biologically active molecules
SIRNA THERAPEUTICS INC19 citations92
US10662428B2May 26, 2020
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC5 citations84
US10351852B2Jul 16, 2019
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC5 citations84
US7517864B2Apr 14, 2009
RNA interference mediated inhibition of vascular endothelial growth factor and vascular endothelial growth factor receptor gene expression using short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC16 citations82
US10889815B2Jan 12, 2021
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
SIRNA THERAPEUTICS INC0 citations63
US7893249B2Feb 22, 2011
Deprotection and purification of oligonucleotides and their derivatives
SIRNA THERAPEUTICS INC2 citations61
US7655790B2Feb 2, 2010
Deprotection and purification of oligonucleotides and their derivatives
SIRNA THERAPEUTICS INC5 citations61
WAVE LIFE SCIENCES LTD
16 patentsUS10450568B2Oct 22, 2019
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD61 citations96
US11013757B2May 25, 2021
Oligonucleotides, compositions and methods thereof
WAVE LIFE SCIENCES LTD19 citations93
US10724035B2Jul 28, 2020
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD24 citations92
US10479995B2Nov 19, 2019
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD30 citations92
US11718638B2Aug 8, 2023
Compounds, compositions and methods for synthesis
WAVE LIFE SCIENCES LTD10 citations84
US11739325B2Aug 29, 2023
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD12 citations83
US11603532B2Mar 14, 2023
Oligonucleotide compositions and methods of use thereof
WAVE LIFE SCIENCES LTD11 citations83
US11596646B2Mar 7, 2023
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD11 citations83
US11634710B2Apr 25, 2023
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD10 citations82
US11597927B2Mar 7, 2023
Oligonucleotide compositions and methods of use thereof
WAVE LIFE SCIENCES LTD11 citations82
US11608355B2Mar 21, 2023
Technologies for oligonucleotide preparation
WAVE LIFE SCIENCES LTD10 citations81
US12391942B2Aug 19, 2025
Oligonucleotide compositions and methods of use thereof
WAVE LIFE SCIENCES LTD2 citations70
US12428442B2Sep 30, 2025
Compounds, compositions and methods for synthesis
WAVE LIFE SCIENCES LTD1 citations63
US12403156B2Sep 2, 2025
Oligonucleotides, compositions and methods thereof
WAVE LIFE SCIENCES LTD0 citations62
US12486505B2Dec 2, 2025
Oligonucleotide compositions and methods thereof
WAVE LIFE SCIENCES LTD0 citations59
US12435105B2Oct 7, 2025
Technologies for oligonucleotide preparation
WAVE LIFE SCIENCES LTD0 citations58
NEXSTAR PHARMACEUTICALS INC
2 patentsGILEAD SCIENCES INC
2 patentsNOVARTIS AG
2 patents(unassigned)
1 patentMERCK SHARPE & DOHME
1 patentMERCK SHARP & DOHME
1 patentBARYZA JEREMY
1 patentBARYZA JEREMY LEE
1 patentRHODE ISLAND EDUCATION
1 patentShowing the top 50 of 57 patents by PatentIndex Score.