Inventor
BRUICE THOMAS
US6 patents
Patents
6 patentsUS5719271AFeb 17, 1998
Covalently cross-linked oligonucleotides
ISIS PHARMACEUTICALS INC114 citations97
US5514786AMay 7, 1996
Compositions for inhibiting RNA activity
ISIS PHARMACEUTICALS INC108 citations97
US5543507AAug 6, 1996
Covalently cross-linked oligonucleotides
ISIS PHARMACEUTICALS INC92 citations96
US6358931B1Mar 19, 2002
Compositions and methods for modulating RNA
ISIS PHARMACEUTICALS INC75 citations95
US5359051AOct 25, 1994
Compounds useful in the synthesis of nucleic acids capable of cleaning RNA
ISIS PHARMACEUTICALS INC59 citations95
US6610663B2Aug 26, 2003
Compositions and methods for modulating RNA
ISIS PHARMACEUTICALS INC4 citations62