P

Inventor

MCKEARN JOHN P

US31 patents
⚠️ This page may combine multiple inventors who share the name “MCKEARN JOHN P”. Patents are grouped by organization below to help distinguish them — per-person disambiguation is on the roadmap.

SEARLE & CO

24 patents
US6858598B1Feb 22, 2005

Method of using a matrix metalloproteinase inhibitor and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia

SEARLE & CO97 citations96
US6440407B1Aug 27, 2002

Methods of ex-vivo expansion of hematopoietic cells using interleukin-3 (IL-3) multiple mutation polypeptides

SEARLE & CO37 citations96
US6030812AFeb 29, 2000

Fusion proteins comprising multiply mutated interleukin-3 (IL-3) polypeptides and second growth factors

SEARLE & CO47 citations96
US6833373B1Dec 21, 2004

Method of using an integrin antagonist and one or more antineoplastic agents as a combination therapy in the treatment of neoplasia

SEARLE & CO64 citations95
US6060047AMay 9, 2000

Co-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell production

SEARLE & CO16 citations92
US5738849AApr 14, 1998

Interleukin-3 (IL-3) variant fusion proteins, their recombinant production, and therapeutic compositions comprising them

SEARLE & CO23 citations92
US6689787B1Feb 10, 2004

Method of using an integrin antagonist and radiation therapy as combination therapy in the treatment of neoplasia

SEARLE & CO33 citations91
US6066318AMay 23, 2000

Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors

SEARLE & CO22 citations91
US6022535AFeb 8, 2000

Treatment of hematopoietic disorders with fusion proteins comprising multiply mutated interleukin-3 (IL-3) polypeptides and second growth factors

SEARLE & CO21 citations91
US6100070AAug 8, 2000

G-CSF receptor agonists

SEARLE & CO35 citations89
US5604116AFeb 18, 1997

Interleukin-3 (IL-3) multiple mutation polypeptides, recombinant production of the same, and corresponding therapeutic methods

SEARLE & CO20 citations89
US6436387B1Aug 20, 2002

Methods of ex-vivo expansion of hematopoietic cells using multivariant IL-3 hematopoiesis chimera proteins

SEARLE & CO19 citations84
US6153183ANov 28, 2000

Co-administration of interleukin-3 mutant polypeptides with CSF's or cytokines for multi-lineage hematopoietic cell production

SEARLE & CO15 citations82
US6093395AJul 25, 2000

Co-administration of interleukin-3 mutant polypeptides with CSF's for multi-lineage hematopoietic cell production

SEARLE & CO14 citations82
US6051217AApr 18, 2000

Therapeutic uses of interleukin-3 (IL-3) multiple mutation polypeptides

SEARLE & CO15 citations82
US6265439B1Jul 24, 2001

Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives

SEARLE & CO7 citations74
US5451604ASep 19, 1995

Halogenated phenylacetonitrile alkylaminoalkylphenyl compounds as immunosuppressives

SEARLE & CO11 citations74
US5247119ASep 21, 1993

Phenylacetonitrilehydroxyalkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives

SEARLE & CO10 citations73
US6451852B2Sep 17, 2002

Phenylacetonitrilealkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives

SEARLE & CO7 citations72
US5543141AAug 6, 1996

Therapeutic methods using interleukin-3 (IL-3) human/murine hybrid polypeptides

SEARLE & CO5 citations72
US5501962AMar 26, 1996

Interleuken-3 (IL-3) human/murine hybrid polypeptides and recombinant production of the same

SEARLE & CO9 citations72
US5486539AJan 23, 1996

Method of using phenylacetonitrilealkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives

SEARLE & CO8 citations72
US5162569ANov 10, 1992

Phenylacetonitrilealkylaminoalkyl-ortho-substituted aryl compounds as immunosuppressives

SEARLE & CO9 citations72
US6254870B1Jul 3, 2001

Thrombopoietin: IL-3 fusion protein

SEARLE & CO7 citations55

(unassigned)

4 patents

PHARMACIA CORP

2 patents

PFIZER

1 patent