Inventor

CHANDRARATNA ROSHANTHA A S

US62 patents

Patents

50 patents

US5455265AOct 3, 1995

Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors

ALLERGAN INC238 citations99

US5407937AApr 18, 1995

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydro-quinolinyl group having retinoid-like activity

ALLERGAN INC107 citations99

US5348972ASep 20, 1994

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

ALLERGAN INC110 citations99

US5326898AJul 5, 1994

Substituted phenylethenyl compounds having retinoid-like biological activity

ALLERGAN INC184 citations99

US5324840AJun 28, 1994

Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects

ALLERGAN INC136 citations99

US5264456ANov 23, 1993

Acetylenes disubstituted with a furyl group and a substituted phenyl group having retinoid like activity

ALLERGAN INC119 citations99

US5264578ANov 23, 1993

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

ALLERGAN INC135 citations99

US5234926AAug 10, 1993

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

ALLERGAN INC155 citations99

US5202471AApr 13, 1993

Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having retinoid like activity

ALLERGAN INC134 citations99

US5183827AFeb 2, 1993

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC127 citations99

US5134159AJul 28, 1992

7-chromanyl esters of phenols and benzoic acids having retinoid-like activity

ALLERGAN INC141 citations99

US5089509AFeb 18, 1992

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

ALLERGAN INC312 citations99

US5053523AOct 1, 1991

Ethynyl-chroman compounds

ALLERGAN INC144 citations99

US5045551ASep 3, 1991

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC166 citations99

US5023341AJun 11, 1991

Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

ALLERGAN INC174 citations99

US5015658AMay 14, 1991

Thiochroman esters of phenols and terephthallates having retinoid-like activity

ALLERGAN INC156 citations99

US5013744AMay 7, 1991

Acetylenes disubstituted with a pyridinyl group and a substituted phenyl group having retinoid like activity

ALLERGAN INC151 citations99

US5006550AApr 9, 1991

Chroman esters of phenols and benzoic acids having retinoid-like activity

ALLERGAN INC152 citations99

US4992468AFeb 12, 1991

Phenylethenyl compounds having retinoid-like activity

ALLERGAN INC152 citations99

US4980369ADec 25, 1990

Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity

ALLERGAN INC160 citations99

US4895868AJan 23, 1990

Thiochroman esters of phenols and terephthallates having retinoid-like activity

ALLERGAN INC149 citations99

US4810804AMar 7, 1989

Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity

ALLERGAN INC179 citations99

US4739098AApr 19, 1988

Ethynylphenyl-containing retinoic acid derivatives

ALLERGAN INC158 citations99

US5391753AFeb 21, 1995

Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity

ALLERGAN INC118 citations98

US5346915ASep 13, 1994

Chromans and thiochromans with phenylethynyl substituents at the 7-position having retinold-like biological activity

ALLERGAN INC114 citations98

US5346895ASep 13, 1994

Chromans and thiochromans with heteroarylethynyl substituents at the 7-position having retinoid-like biological activity

ALLERGAN INC117 citations98

US5278318AJan 11, 1994

Process of synthesizing acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group

ALLERGAN INC117 citations98

US5248777ASep 28, 1993

Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

ALLERGAN INC118 citations98

US5175185ADec 29, 1992

Acetylenes disubstituted with a heteroaromatic group and a substituted phenyl group having retinoid like activity

ALLERGAN INC135 citations98

US5162546ANov 10, 1992

Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC127 citations98

US5068252ANov 26, 1991

Methods of using phenylethenyl compounds having retinoid-like activity

ALLERGAN INC131 citations98

US5468879ANov 21, 1995

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

ALLERGAN INC90 citations97

US5380877AJan 10, 1995

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

ALLERGAN INC102 citations97

US5354752AOct 11, 1994

Disubstituted acetylenes bearing a diazinyl group having retinoid like activity

ALLERGAN INC100 citations97

US5348975ASep 20, 1994

7-chromanyl esters of phenols and benzoic acids having retinoid-like activity

ALLERGAN INC105 citations97

US5272156ADec 21, 1993

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC111 citations97

US5677451AOct 14, 1997

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

ALLERGAN INC47 citations96

US5677323AOct 14, 1997

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1, 2, 3, 4, -tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC55 citations96

US5663347ASep 2, 1997

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

ALLERGAN INC74 citations96

US5616597AApr 1, 1997

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4--tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC78 citations96

US5599819AFeb 4, 1997

Acetylenes disubstituted with a thienyl or furyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4 - tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC68 citations96

US5534516AJul 9, 1996

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1, 2, 3, 4-tetrahydroquinolinyl group having retinoid-like activity

ALLERGAN INC81 citations96

US5516904AMay 14, 1996

Acetylenes disubstituted with a heteroaromatic group and a substituted phenyl group having retinoid like activity

ALLERGAN INC83 citations96

US5434173AJul 18, 1995

Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity

ALLERGAN INC102 citations96

US5414007AMay 9, 1995

Acetylenes disubstituted with a thiazole group and a substituted phenyl group having retinoid like activity

ALLERGAN INC98 citations96

US5354776AOct 11, 1994

Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid-like activity

ALLERGAN INC69 citations96

US5349105ASep 20, 1994

Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having retinoid like activity

ALLERGAN INC107 citations96

US5324744AJun 28, 1994

Showing the top 50 of 62 patents by PatentIndex Score.

CHANDRARATNA ROSHANTHA A S

Patents

Method of treatment with compounds having selective agonist-like activity on RXR retinoid receptors

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydro-quinolinyl group having retinoid-like activity

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

Substituted phenylethenyl compounds having retinoid-like biological activity

Method of treatment with compounds having retinoid-like activity and reduced skin toxicity and lacking teratogenic effects

Acetylenes disubstituted with a furyl group and a substituted phenyl group having retinoid like activity

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having retinoid like activity

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

7-chromanyl esters of phenols and benzoic acids having retinoid-like activity

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

Ethynyl-chroman compounds

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

Thiochroman esters of phenols and terephthallates having retinoid-like activity

Acetylenes disubstituted with a pyridinyl group and a substituted phenyl group having retinoid like activity

Chroman esters of phenols and benzoic acids having retinoid-like activity

Phenylethenyl compounds having retinoid-like activity

Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl or thiochromanyl group having retinoid-like activity

Thiochroman esters of phenols and terephthallates having retinoid-like activity

Acetylenes disubstituted with a phenyl group and a heterobicyclic group having retinoid-like activity

Ethynylphenyl-containing retinoic acid derivatives

Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity

Chromans and thiochromans with phenylethynyl substituents at the 7-position having retinold-like biological activity

Chromans and thiochromans with heteroarylethynyl substituents at the 7-position having retinoid-like biological activity

Process of synthesizing acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group

Process and intermediates for preparing compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity

Acetylenes disubstituted with a heteroaromatic group and a substituted phenyl group having retinoid like activity

Acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Methods of using phenylethenyl compounds having retinoid-like activity

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

Disubstituted acetylenes bearing heteroaromatic and heterobicyclic groups having retinoid like activity

Disubstituted acetylenes bearing a diazinyl group having retinoid like activity

7-chromanyl esters of phenols and benzoic acids having retinoid-like activity

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1, 2, 3, 4, -tetrahydroquinolinyl group having retinoid-like activity

Disubstituted acetylenes bearing heterobicyclic groups and heteroaromatic or phenyl groups having retinoid like activity

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4--tetrahydroquinolinyl group having retinoid-like activity

Acetylenes disubstituted with a thienyl or furyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4 - tetrahydroquinolinyl group having retinoid-like activity

Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1, 2, 3, 4-tetrahydroquinolinyl group having retinoid-like activity

Acetylenes disubstituted with a heteroaromatic group and a substituted phenyl group having retinoid like activity

Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity

Acetylenes disubstituted with a thiazole group and a substituted phenyl group having retinoid like activity

Acetylenes disubstituted with a heteroaromatic group and a tetralin group and having retinoid-like activity

Alkyl, alkoxy and thioalkoxy substituted diphenyl acetylenes having retinoid like activity

7-chromanyl esters of phenols and benzoic acids having retinoid-like activity

Tetralin esters of phenols or benzoic acids having retinoid like activity

Ethynylheteroaromatic-acids having retinoic acid-like activity